herbicide in some countries. Analogues of MPTP include 2′-NH2-MPTP (2′-amino-MPTP) and 2′-CH3-MPTP (2′-methyl-MPTP). The haloperidol-derived monoaminergic...

2′-NH2-MPTP, also known as 2′-amino-MPTP, is a monoaminergic neurotoxin that was derived from MPTP and is used in scientific research to lesion brain monoaminergic...

inhibitor clorgyline. A close analogue of 2′-CH3-MPTP is 2′-NH2-MPTP, which, in contrast to 2′-CH3-MPTP and MPTP, is a serotonergic and noradrenergic neurotoxin...

6-Methylenedioxy-2-aminoindan (MDAI) (weak; alone and with amphetamine) 2′-NH2-MPTP (2′-amino-MPTP) Haloperidol HPP+ (haloperidol pyridinium) HPTP 2,4,5-Trihydroxyamphetamine...

Pantheon Books. ISBN 0-679-42465-2. OCLC 31608154. Jackson-Lewis, Vernice; Przedborski, Serge (Jan 2007). "Protocol for the MPTP mouse model of Parkinson's...

pathology to Parkinson's disease in aged rhesus monkeys from MPTP. Therefore, the mechanism behind MPTP as it relates to Parkinson's disease is not fully understood...

sports-related concussions, and some forms of chemical poisoning such as MPTP, can lead to substantial cell loss, producing a parkinsonian syndrome that...

Occupational Safety and Health has set a recommended exposure limit (REL) of 2 mg/m3 and recommended that workers avoid concurrent exposure to ethylene dibromide...

(R)-MDMA was significantly longer than that of the (S)-enantiomer (5.8 ± 2.2 hours vs 3.6 ± 0.9 hours). However, because MDMA excretion and metabolism...

increased sociability. Mephedrone is rapidly absorbed, with a half-life of about 2 hours, and is primarily metabolized by CYP2D6 enzymes. Its effects are dose-dependent...

methyl viologen, is a toxic organic compound with the chemical formula [(C6H7N)2]Cl2. It is classified as a viologen, a family of redox-active heterocycles...

and this is often achieved either with oxidopamine or another neurotoxin MPTP. Both these agents likely destroy neurons by generating reactive oxygen species...

impact of fungicides, insecticides and herbicides" (PDF). Prevention Today. 2 (1–2): 47–62. Retrieved 2024-07-12. Mancozeb in the Pesticide Properties DataBase...

(cyperquat) MPTP N-Methylnorsalsolinol Norsalsolinol Oxidopamine (6-OHDA) Paraquat Rotenone Salsolinol Ziram Noradrenergic 2′-NH2-MPTP (2′-amino-MPTP) 2,4,5-THA...

course of the reaction" (PDF). J. Biol. Chem. 249 (2): 454–458. doi:10.1016/S0021-9258(19)43051-2. PMID 4809526. Archived (PDF) from the original on 7...

arises in the body as the toxic metabolite of the closely related compound MPTP. MPTP is converted in the brain into MPP+ by the enzyme MAO-B, ultimately causing...

PIA used as a radiopharmaceutical and diagnostic agent. 5-Iodo-2-aminoindane (5-IAI), the 2-aminoindane analogue of PIA, was an attempt to make a non-neurotoxic...

rats. Substituted tetrahydroisoquinoline Norsalsolinol 6-Hydroxydopamine MPTP Rotenone Pesnot, Thomas; Gershater, Markus C.; Ward, John M.; Hailes, Helen...

"Pharmacokinetic interactions between alcohol and other drugs". Clin Pharmacokinet. 33 (2): 79–90. doi:10.2165/00003088-199733020-00001. PMID 9260032. S2CID 45547473...

Paul Margot (2012). "Fungicides, Agricultural, 2. Individual Fungicides". Fungicides, Agricultural, 2. Individual Fungicides. Ullmann's Encyclopedia of...

5,7-Dihydroxytryptamine MPTP Oxidopamine Daw NW, Videen TO, Parkinson D, Rader RK (1985). "DSP-4 (N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine) Depletes...

MDAI, also known as 5,6-methylenedioxy-2-aminoindane, is an entactogen drug of the 2-aminoindane group which is related to MDMA and produces similar subjective...

5-Iodo-2-aminoindane (5-IAI) is an entactogen drug of the 2-aminoindane group. Human anecdotal reports suggest that it is entactogenic but produces little...

The Methylmercury compound has an overall charge of +1, with Hg in the +2 oxidation state. Methylmercury exists as a substituent in many complexes of...

Zn(S2CNR2)2 are dimeric, i.e. their proper formula is [Zn(S2CNR2)2]2. Each Zn center is in a distorted pentacoordinate site, with four Zn–S bonds of 2.3 Å length...

5-Methoxy-6-methyl-2-aminoindane (MMAI) is a drug of the 2-aminoindane group developed in the 1990s by a team led by David E. Nichols at Purdue University...

5-hydroxytryptamine and 5-hydroxyindolacetic acid by an arylalkylamine". Life Sciences. 2 (11): 828–833. doi:10.1016/0024-3205(63)90094-8. PMID 14078137. Fuller RW...

HPTP is a monoaminergic neurotoxin related to MPTP. It is the dehydration product of haloperidol. The agent is specifically a dopaminergic and serotonergic...

22 (9): 1921. Bibcode:1983PChem..22.1921O. doi:10.1016/0031-9422(83)80013-2. Rezvani, A; Overstreet, David H; Perfumi, Marina; Massi, Maurizio (2003)...

effects". Drug Development Research. 51 (2): 52–65. doi:10.1002/1098-2299(200010)51:2<52::AID-DDR2>3.0.CO;2-H. eISSN 1098-2299. ISSN 0272-4391. S2CID 84029575...