5-Methylcytosine is a methylated form of the DNA base cytosine (C) that regulates gene transcription and takes several other biological roles. When cytosine...
22 KB (2,598 words) - 17:10, 28 March 2024
Methylcytosine may refer to: 5-Methylcytosine 1-Methylcytosine, a nucleic acid in Hachimoji DNA N(4)-Methylcytosine 6-Methylcytosine Cytosine Nucleic acid...
538 bytes (57 words) - 03:49, 1 March 2021
Deamination (section 5-methylcytosine)
vitro through the use of bisulfite, which deaminates cytosine, but not 5-methylcytosine. This property has allowed researchers to sequence methylated DNA to...
6 KB (708 words) - 19:27, 26 May 2023
and cytosine. The modified bases are N6-methyladenine, 5-methylcytosine and N4-methylcytosine. Cytosine methylation is widespread in both eukaryotes and...
114 KB (13,166 words) - 05:13, 18 May 2024
oxidation of 5-methylcytosine, a reaction mediated by TET enzymes. Its molecular formula is C5H7N3O2. Every mammalian cell seems to contain 5-Hydroxymethylcytosine...
16 KB (1,744 words) - 17:52, 18 March 2024
groups to the DNA, mostly at CpG sites, to convert cytosine to 5-methylcytosine. 5-Methylcytosine performs much like a regular cytosine, pairing with a guanine...
161 KB (18,430 words) - 18:39, 23 May 2024
Modified Cytosine N4-Methylcytosine 5-Carboxylcytosine 5-Formylcytosine 5-Glycosylhydroxymethylcytosine 5-Hydroxycytosine 5-Methylcytosine Modified Thymidine...
166 KB (17,845 words) - 02:08, 24 May 2024
modified DNA base methylcytosine to 5-hydroxymethylcytosine. The first mechanistic reports showed tissue-specific accumulation of 5-hydroxymethylcytosine...
25 KB (2,576 words) - 13:09, 21 January 2024
Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function...
17 KB (1,893 words) - 03:46, 22 January 2024
Methylation (redirect from 5-O-Methylation)
present in eukaryotes. 5-methylcytosine (5-mC) also commonly occurs in various RNA molecules. Recent data strongly suggest that m6A and 5-mC RNA methylation...
28 KB (3,051 words) - 02:03, 23 April 2024
also be methylated into 5-methylcytosine by an enzyme called DNA methyltransferase or be methylated and hydroxylated to make 5-hydroxymethylcytosine. The...
10 KB (903 words) - 20:23, 21 May 2024
islands. Cytosines in CpG dinucleotides can be methylated to form 5-methylcytosines. Enzymes that add a methyl group are called DNA methyltransferases...
51 KB (5,474 words) - 16:32, 19 April 2024
cytosine reacted much faster to sodium bisulfite treatment than did 5-methylcytosine. This difference in reaction rates created the possibility of identifying...
22 KB (2,517 words) - 14:03, 6 September 2023
acid chain has been formed. In DNA, the most common modified base is 5-methylcytosine (m5C). In RNA, there are many modified bases, including those contained...
14 KB (1,376 words) - 14:57, 19 May 2024
DNA cytosine to form 5-methylcytosine. This usually occurs in the DNA sequence CpG, changing the DNA at the CpG site from CpG to 5-mCpG. Methylation of...
17 KB (2,080 words) - 17:17, 26 April 2024
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine. It is found in ribonucleic acids of animal, plant, and bacterial origin. Dunn...
2 KB (53 words) - 16:08, 27 April 2023
ten-eleven translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation. 5-Methylcytosine (see first Figure) is a methylated...
32 KB (3,984 words) - 05:42, 27 April 2024
modifications include DNA cytosine methylation to form 5-methylcytosine and 5-methylcytosine demethylation. These modifications are critical for cell...
24 KB (2,758 words) - 02:37, 23 May 2024
deamination of guanine. (Thymidine products following deamination of 5-methylcytosine are more difficult to recognize, but can be repaired by mismatch-specific...
29 KB (3,489 words) - 15:28, 28 February 2024
into uracil, but does not affect 5-methylcytosine, a methylated form of cytosine with a methyl group attached to carbon 5. When the bisulfite-treated DNA...
10 KB (1,062 words) - 08:25, 30 March 2024
Bisulfite sequencing (section 5-Hydroxymethylcytosine)
DNA with bisulfite converts cytosine residues to uracil, but leaves 5-methylcytosine residues unaffected. Therefore, DNA that has been treated with bisulfite...
34 KB (4,084 words) - 21:59, 8 January 2024
central roles of ten-eleven translocation methylcytosine dioxygenases (TETs) in the demethylation of 5-methylcytosine to form cytosine. As reviewed in 2018...
49 KB (5,387 words) - 17:07, 6 April 2024
modifications include DNA cytosine methylation to form 5-methylcytosine and 5-methylcytosine demethylation. These modifications are critical for cell...
78 KB (9,015 words) - 21:00, 21 May 2024
formula is C5H5N3O2. Similarly to the related cytosine modifications 5-Methylcytosine (5mC) and 5hmC, 5fC is broadly distributed across the mammalian genome...
9 KB (917 words) - 13:13, 24 May 2023
(where 5' cytosine is followed by 3' guanine or CpG sites). 5-methylcytosine (5-mC) is a methylated form of the DNA base cytosine (see Figure). 5-mC is...
58 KB (6,780 words) - 04:35, 23 May 2024
molecular biology in mammals, DNA demethylation causes replacement of 5-methylcytosine (5mC) in a DNA sequence by cytosine (C) (see figure of 5mC and C)....
42 KB (5,154 words) - 13:37, 14 February 2024
Epitranscriptome (section 5-methylcytosine (m5C))
reamination, or the conversion of 5-methylcytosine back into cytosine, has not been observed in RNA. 5-methylcytosine modifications are typically found...
61 KB (7,732 words) - 20:34, 13 May 2024
messenger RNA from its target gene. 5-Methylcytosine (5-mC) is a methylated form of the DNA base cytosine (see figure). 5-mC is an epigenetic marker found...
26 KB (2,836 words) - 13:21, 3 December 2023
form 5-methylcytosine and 5-methylcytosine demethylation. DNA cytosine methylation is catalyzed by DNA methyltransferases (DNMTs). Methylcytosine demethylation...
57 KB (6,880 words) - 23:11, 18 May 2024
genomes, possibly due to the molecular mechanisms that generate them. 5-Methylcytosine is more prone to transition than unmethylated cytosine, due to spontaneous...
2 KB (228 words) - 03:44, 15 December 2023