• Thumbnail for Angiotensin-converting enzyme 2
    Angiotensin-converting enzyme 2 (ACE2) is an enzyme that can be found either attached to the membrane of cells (mACE2) in the intestines, kidney, testis...
    45 KB (5,270 words) - 19:19, 10 June 2025
  • Thumbnail for SARS-CoV-2
    sneezes. It enters human cells by binding to angiotensin-converting enzyme 2 (ACE2), a membrane protein that regulates the renin–angiotensin system. During...
    122 KB (12,484 words) - 09:57, 10 June 2025
  • Thumbnail for COVID-19
    progression, but acute myocardial injuries may also be related to ACE2 receptors in the heart. ACE2 receptors are highly expressed in the heart and are involved...
    288 KB (32,893 words) - 08:29, 13 June 2025
  • MERS-CoV is most closely related. All HKU5 coronaviruses have been shown to use ACE2 from their natural host species, Pipistrellus abramus, to infect their hosts...
    6 KB (601 words) - 04:26, 13 June 2025
  • Thumbnail for Coronavirus
    recognizing different protein receptors such as angiotensin-converting enzyme 2 (ACE2), aminopeptidase N (APN), and dipeptidyl peptidase 4 (DPP4). A subset of...
    96 KB (10,611 words) - 20:30, 27 May 2025
  • Thumbnail for SARS-related coronavirus
    viruses enter host cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor. The SARSr-CoV species is a member of the genus Betacoronavirus...
    54 KB (6,054 words) - 03:37, 2 June 2025
  • Thumbnail for Pulmonary alveolus
    vasculature. Because of the high expression of angiotensin-converting enzyme 2 (ACE2) in type II alveolar cells, the lungs are susceptible to infections by some...
    28 KB (3,215 words) - 12:56, 27 January 2025
  • regulate the enzyme. Angiotensin converting enzyme (ACE2) is regulated by PIP2 localization. The ACE2 enzyme is palmitoylated which drives the protein into...
    5 KB (621 words) - 05:07, 21 October 2024
  • Thumbnail for Myocarditis
    of many types of coronaviruses, including the SARS-CoV-2 virus, through ACE2 receptors present in heart muscle may be responsible for direct viral injury...
    59 KB (6,426 words) - 05:09, 26 May 2025
  • Thumbnail for Alzheimer's disease and COVID-19
    increased ACE2 in the brain and AD, however this remains controversial. ACE2 has been shown to potentially play a protective role in AD, as ACE2 decreases...
    34 KB (3,555 words) - 03:59, 27 May 2025
  • Thumbnail for Coronavirus spike protein
    (which causes COVID-19) all interact with angiotensin-converting enzyme 2 (ACE2). The S2 region contains the fusion peptide and other fusion infrastructure...
    74 KB (7,315 words) - 01:43, 13 June 2025
  • Thumbnail for SARS-CoV-1
    primary human receptor of the virus is angiotensin-converting enzyme 2 (ACE2) and hemaglutinin (HE), first identified in 2003, and the viral spike protein...
    34 KB (4,008 words) - 07:02, 2 June 2025
  • Thumbnail for Glycan–protein interaction
    COVID-19, employs its extensively glycosylated spike (S) protein to bind to the ACE2 receptor, allowing it to enter host cells. The spike protein is a trimeric...
    26 KB (2,802 words) - 16:00, 8 June 2025
  • Thumbnail for Variants of SARS-CoV-2
    RBD-hACE2 complex, thus, enhancing the binding affinity of RBD to hACE2. However, the K417T mutation disfavours complex formation between RBD and hACE2, which...
    227 KB (21,893 words) - 18:30, 31 May 2025
  • Thumbnail for MERS-related coronavirus
    exopeptidase, angiotensin converting enzyme 2 (ACE2). However, it was later discovered that neutralization of ACE2 by recombinant antibodies does not prevent...
    43 KB (4,598 words) - 18:26, 10 June 2025
  • SARS-Cov-2 infection resulting in ARDS related to COVID-19. Abbreviations: ACE2: Angiotensin-converting enzyme 2, CXCL9: Chemokine (C–X–C motif) ligand 9...
    25 KB (2,786 words) - 02:05, 24 June 2024
  • Thumbnail for Chronic obstructive pulmonary disease
    combined with smoking; smoking induces the upregulation of the expression of ACE2, a receptor for the SARS-CoV-2 virus. The primary risk factor for COPD globally...
    155 KB (16,709 words) - 20:58, 10 June 2025
  • Thumbnail for Human coronavirus NL63
    positive-sense, single-stranded RNA virus which enters its host cell by binding to ACE2. Infection with the virus has been confirmed worldwide, and has an association...
    19 KB (2,095 words) - 15:17, 29 April 2025
  • (Ultrawide) 13 MP (Telephoto) 2 MP (Monochrome) 16 MP 4000 mAh 65W SuperVOOC 2.0 Ace2 April 2020 6.55" 2400×1080 90 Hz AMOLED Qualcomm Snapdragon 865 48 MP (Wide)...
    90 KB (3,729 words) - 10:03, 9 May 2025
  • Thumbnail for Symptoms of COVID-19
    COVID-19 patients.[citation needed] The binding of the SARS-CoV-2 virus through ACE2 receptors present in heart tissue may be responsible for direct viral injury...
    55 KB (6,566 words) - 02:11, 29 April 2025
  • Thumbnail for Heparan sulfate
    role in SARS-CoV-2 infection, particularly when the virus attaches with ACE2. The major cell membrane HSPGs are the transmembrane syndecans and the...
    36 KB (4,162 words) - 19:16, 23 May 2025
  • Thumbnail for Histamine H1 receptor
    addition to the main receptor ACE2. HRH1 also synergistically enhanced hACE2-dependent viral entry by interacting with hACE2. Antihistamine drugs effectively...
    15 KB (1,745 words) - 20:38, 6 January 2025
  • Thumbnail for Multicellular organism
    called "snowflake", caused by the loss of a single transcription factor Ace2. "Snowflake" yeast grow into multicellular clusters that sediment quickly;...
    43 KB (4,918 words) - 19:30, 9 June 2025
  • spike proteins of both natural and chimaeric SARS-like coronaviruses to ACE2 receptors in human, civet and horseshoe bat cells, to determine the mechanism...
    26 KB (2,506 words) - 21:11, 9 April 2025
  • Thumbnail for Arm Holdings
    will also implement extensions to the ARMv8 architecture equivalent to HPC-ACE2 that Fujitsu is developing with ARM Holdings. The Cray XC50-series supercomputer...
    73 KB (6,381 words) - 08:37, 14 June 2025
  • Thumbnail for SARS-CoV-2 Delta variant
    leucine-to-arginine substitution, confers stronger affinity of the spike protein for the ACE2 receptor and decreased recognition capability of the immune system. P681R...
    129 KB (12,263 words) - 11:28, 9 June 2025
  • Thumbnail for Origin of SARS-CoV-2
    Zoonotic transmission is also supported by the fact that RaTG13 binds to hACE2, although the fit is not optimal. The investigative team noted the requirement...
    114 KB (13,181 words) - 13:06, 4 June 2025
  • Thumbnail for Zoonotic origins of COVID-19
    example, spike proteins in SARS-related coronaviruses coevolve with bat ACE2 receptors in an evolutionary arms race. Bats, along with their viruses, have...
    44 KB (5,250 words) - 10:18, 10 June 2025
  • Thumbnail for TMPRSS2
    SARS-CoV-2 infection. The enzyme Adam17 has similar ACE2 cleavage activity as TMPRSS2, but by forming soluble ACE2, Adam17 may actually have the protective effect...
    25 KB (2,644 words) - 17:17, 5 February 2025
  • Thumbnail for COVID-19 testing
    surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction". Nature Biotechnology. 38 (9): 1073–1078...
    180 KB (20,980 words) - 00:18, 6 June 2025