ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin...

magnitude of fibrosis being in proportion to the increase in TGF-β levels. ACTA2 is associated with the TGF-β pathway that enhances contractile properties...

SMAC, previous names of Comprehensive metabolic panel blood tests α-SMA or ACTA2, an actin protein Spinal muscular atrophy, a severe neuromuscular disorder...

(MSMDS) is a genetic disorder caused by R179 missense mutations in the ACTA2 gene. Initially described as a case report in 1999, it was characterized...

Additionally, genetic testing for pathogenic variants in genes such as FBN1 and ACTA2 may confirm a familial predisposition to aortic pathology. Early detection...

disease. Moyamoya disease-5 (MYMY5; 614042) is caused by mutation in the ACTA2 gene (102620) on the long arm of chromosome 10 (10q23.3); and moyamoya disease-6...

dissection FOXE3, SMAD2, LOX, MAT2A, ELN, HEY2, TGFB3, TGFBR1, TGFBR2, FBN1, ACTA2, MYLK, SMAD3, PRKG1, MFAP5, TGFB2, SMAD4, MYH11 dominant Feingold syndrome...

mammalian protein ACTA1, actin alpha 1 (skeletal muscle), human protein ACTA2, actin alpha 2 (smooth muscle), human protein Actin assembly-inducing protein...

which is a general mesenchymal marker, α-smooth muscle actin (human gene = ACTA2), and for palladin, which is a cytoskeletal actin scaffold protein. They...

of CAF Markers Name of markers Functions α-smooth muscle actin (α-SMA, ACTA2) Marker for myofibroblasts Fibroblast activation protein (FAP) Marker for...

HGNC:15814 Q9NR19 202 ACSS3 HGNC:24723 Q9H6R3 203 ACTA1 HGNC:129 P68133 204 ACTA2 HGNC:130 P62736 205 ACTB HGNC:132 P60709 206 ACTBL2 HGNC:17780 Q562R1 207...

are involved in skeletal striated muscle (ACTA1), smooth muscle tissue (ACTA2), intestinal muscles (ACTG2) and cardiac muscle (ACTC1). The actin in the...

Milewicz DM. Mutations in genes encoding smooth muscle contractile proteins, ACTA2 and MYH11, cause hyperplastic vasculomyopathy and lead to diffuse and diverse...

being in proportion to increase in TGF-β levels. Studies have shown that ACTA2 is associated with TGF-β pathway that enhances contractile properties of...

in cell culture. T98G cells are known for having high expression of the ACTA2 gene, which is involved in cell motility and structure. T98G cells are polyploidy...

for example vSMCs but not pericytes express alpha-smooth muscle actin (ACTA2). Nowadays, distinctively characterizing these cells requires a combination...

original on 18 February 2019. Retrieved 17 February 2019. "#stopACTA2 events". stop ACTA2 – Save Your Internet. 24 August 2018. Archived from the original...

Nili; et al. (11 November 2007). "Mutations in Smooth Muscle Alpha-actin (ACTA2) Lead to Thoracic Aortic Aneurysms and Dissections". Nature Genetics. 39...

vimentin proteins but not epithelial membrane antigen (also termed MUC1), ACTA2 (also termed α-SMA), desmin, HMB-45, keratin, S100, or MLANA (also termed...

(located on 9q22.33) TGFBR2 (located on 3p24.1) FBN1 (located on 15q21.1) ACTA2 (located on 10q23.31 MYLK (located on 3q21.1) SMAD3 (located on 15q22.33)...

time they turn on the expression of vimentin, alpha smooth muscle actin (ACTA2), and fibroblast-specific protein 1 (FSP1). They also produce extracellular...

analyses find that the LGMS tumors' spindle-shaped cells commonly express ACTA2 (also known α-smooth muscle actin) and desmin (i.e. an intermediate filament...

MYH11 gene is responsible for the smooth muscle myosin heavy chain and ACTA2 at TAAD4 loci encodes for smooth muscle alpha-actin. A nonsynonymous amino...

account for approximately 2% of familial TAAD. Additionally, mutations in the ACTA2 gene are thought to account for approximately 10-14% of familial TAAD. The...

mesenchyme. These molecules include vimentin, alpha smooth muscle actin (ACTA2) and fibroblast-specific protein 1 (FSP1). EP300, MITF PIAS4, SMAD2, and...

Their lungs had lumpy surfaces, various other malformations, low levels of ACTA2 (i.e., actin alpha 2, also termed alpha smooth muscle actin or α-SMA) in...

Pannu H, Tran-Fadulu V, et al. (2007). "Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections". Nature Genetics. 39...

(also termed EMA) protein in 46% of cases; desmin protein in 22% of cases; ACTA2 (also termed α-SMA), CD34, and STAT6 proteins in 10% or fewer cases, and...

thoracic 4; 132900; MYH11 Aortic aneurysm, familial thoracic 6; 611788; ACTA2 Aortic valve disease; 109730; NOTCH1 Apert syndrome; 101200; FGFR2 Aphakia...