• Thumbnail for AP2 adaptor complex
    The AP2 adaptor complex is a multimeric protein that works on the cell membrane to internalize cargo in clathrin-mediated endocytosis. It is a stable...
    11 KB (1,387 words) - 07:30, 15 November 2023
  • AP complexes in mammals. AP1 is responsible for the transport of lysosomal hydrolases between the trans-Golgi network, and endosomes. AP2 adaptor complex...
    7 KB (799 words) - 16:10, 22 May 2025
  • Thumbnail for Adaptor-related protein complex 2, alpha 1
    adaptin subunit of the adaptor protein 2 (AP2 adaptors) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two...
    8 KB (1,005 words) - 22:33, 24 February 2025
  • Thumbnail for AP4S1
    hypothesized that AP4-complex-mediated trafficking plays a crucial role in brain development and functioning. AP2 adaptor complex GRCh38: Ensembl release...
    2 KB (303 words) - 14:26, 2 December 2021
  • Exomer (category Protein complexes)
    this figure. AP2 adaptor complex Clathrin vesicles COPII vesicles Paczkowski JE, Richardson BC, Fromme JC (July 2015). "Cargo adaptors: structures illuminate...
    3 KB (290 words) - 20:23, 24 September 2023
  • acids AP2 adaptors (AP-2 complex), which aid clathrin mediated endocytosis Apetala 2 (AP2), a plant transcription factor Automotive products AP2, Automatic...
    1 KB (199 words) - 20:36, 16 April 2022
  • Thumbnail for Adaptor complexes medium subunit domain
    adaptor complexes medium subunit domain is a protein domain found at the C-terminus of the mu subunit from various clathrin adaptor protein complexes...
    3 KB (339 words) - 19:21, 21 December 2022
  • Thumbnail for Beta2-adaptin C-terminal domain
    constitutive internalization of GABAA receptors mediated by clathrin and AP2 adaptor complex". J. Neurochem. 101 (4): 898–905. doi:10.1111/j.1471-4159.2006.04399...
    8 KB (908 words) - 16:48, 5 July 2023
  • Thumbnail for Vesicular transport adaptor protein
    Vesicular transport adaptor proteins are proteins involved in forming complexes that function in the trafficking of molecules from one subcellular location...
    21 KB (2,331 words) - 09:27, 5 October 2024
  • Thumbnail for AP2B1
    encoded by this gene is one of two large chain components of the AP2 adaptor complex, which serves to link clathrin to receptors in coated vesicles. The...
    10 KB (1,298 words) - 22:09, 6 March 2024
  • polymerised clathrin with adaptor complexes bound to the membrane. Schmid EM, Ford MG, Burtey A, et al. (September 2006). "Role of the AP2 beta-appendage hub...
    1 KB (130 words) - 03:13, 3 December 2023
  • Thumbnail for AAK1
    Adaptor-associated protein kinase 1 also known as AP2-associated protein kinase 1 is an enzyme that in humans is encoded by the AAK1 gene and is involved...
    7 KB (793 words) - 14:51, 24 May 2024
  • Thumbnail for Proteinase-activated receptor 1
    cell surface. Uncleaved PAR1 in the cell membrane gets bound by the AP2 adaptor complex at a tyrosine motif on the intracellular C-terminus, which stimulates...
    19 KB (2,285 words) - 10:53, 11 May 2024
  • Thumbnail for AP2M1
    of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is...
    10 KB (1,313 words) - 06:14, 1 January 2024
  • Thumbnail for Muniscins
    Muniscins (category Protein complexes)
    evolved from part of an ancient cargo adaptor protein complex named TSET. AP2 adaptor complex Vesicular transport adaptor protein Umasankar PK, Ma L, Thieman...
    6 KB (589 words) - 02:17, 23 October 2024
  • H I J K L M N O P Q R S T U V W X Y Z 5-HT3 receptor ACCN1 ANO1 AP2 adaptor complex Aaron Klug Acid-sensing ion channel Activating function Active transport...
    15 KB (1,545 words) - 18:32, 17 August 2024
  • Thumbnail for AP2A2
    108.3.833. PMC 2115374. PMID 2564002. "Entrez Gene: AP2A2 adaptor-related protein complex 2, alpha 2 subunit". Chen H, Fre S, Slepnev VI, Capua MR, Takei...
    9 KB (1,092 words) - 17:28, 24 January 2024
  • Thumbnail for Arrestin
    to elements of the internalization machinery, clathrin and clathrin adaptor AP2, which promotes receptor internalization via coated pits and subsequent...
    19 KB (1,930 words) - 17:52, 18 June 2025
  • Thumbnail for AP1M2
    AP-1 complex subunit mu-2 is a protein that in humans is encoded by the AP1M2 gene. This gene encodes a subunit of the heterotetrameric adaptor-related...
    8 KB (1,041 words) - 17:27, 24 January 2024
  • Thumbnail for EPN1
    interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1; MIM 601026), and clathrin (see MIM 118960), as well as with other...
    7 KB (697 words) - 01:53, 3 December 2023
  • Thumbnail for AP2S1
    AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene. One of two major clathrin-associated adaptor complexes, AP-2, is a...
    6 KB (783 words) - 15:35, 29 September 2022
  • Thumbnail for SNX9
    Lundmark R; Carlsson SR (2002). "The beta-appendages of the four adaptor-protein (AP) complexes: structure and binding properties, and identification of sorting...
    8 KB (1,009 words) - 01:27, 3 December 2023
  • Thumbnail for TGOLN2
    regulates sorting signal recognition by the clathrin-associated adaptor complex AP2" (PDF). Mol. Cell. 18 (5): 519–31. doi:10.1016/j.molcel.2005.04.019...
    5 KB (561 words) - 21:42, 3 March 2023
  • Thumbnail for Endocytosis
    and are not representative of the membrane as a whole. AP2 adaptors are multisubunit complexes that perform this function at the plasma membrane. The...
    25 KB (2,981 words) - 01:09, 18 October 2024
  • Thumbnail for G protein-coupled receptor
    to β2-adrenoreceptors acts as an adaptor for binding with clathrin, and with the beta-subunit of AP2 (clathrin adaptor molecules); thus, the arrestin here...
    82 KB (9,408 words) - 19:11, 8 June 2025
  • Thumbnail for Valosin-containing protein
    (November 1995). "Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP". Genomics...
    49 KB (5,868 words) - 04:33, 6 January 2025
  • Thumbnail for Transcription factor
    Class: E1A-like factors 0.5 Class: AP2/EREBP-related factors 0.5.1 Family: AP2 0.5.2 Family: EREBP 0.5.3 Superfamily: AP2/B3 0.5.3.1 Family: ARF 0.5.3.2 Family:...
    75 KB (8,351 words) - 11:12, 9 June 2025
  • Thumbnail for Acorn Electron
    production of the unit had ceased in November 1985. The Advanced Plus 2 (AP2) ROM was later sold by PRES as a replacement ROM for the Plus 1, of whose...
    167 KB (18,191 words) - 16:04, 16 June 2025
  • Thumbnail for VPS26A
    identifiable clathrin- or AP2-binding sequences, and therefore cannot form stable intramolecular contacts with clathrin and AP2, which has been observed...
    11 KB (1,457 words) - 16:02, 13 February 2025
  • salinity stresses, including identifying the role of transcript isoforms of AP2-EREBP. Investigation of gene expression during biofilm formation by the fungal...
    120 KB (12,519 words) - 13:36, 25 January 2025