Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...

of RNA splicing occur in nature; the type of splicing depends on the structure of the spliced intron and the catalysts required for splicing to occur...

However, such transcripts are also produced by splicing errors in a process called "noisy splicing," and are also potentially translated into protein...

Serine/arginine-rich splicing factor 1 (SRSF1) also known as alternative splicing factor 1 (ASF1), pre-mRNA-splicing factor SF2 (SF2) or ASF1/SF2 is a...

expression. Alternative splicing can be affected by various factors, including mutations such as chromosomal translocation. In prokaryotes, splicing is done...

abundance of alternative splicing, which occurs in most human genes, and the specificity in which splicing is carried out in vivo. Splicing is distinctly...

and alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA...

due to a variation in a single nucleotide (840.C→T) – undergoes alternative splicing at the junction of intron 6 to exon 8, with only 10–20% of SMN2 transcripts...

multiple alternative splicing modes: exon skipping (most common splicing mode in humans and higher eukaryotes), mutually exclusive exons, alternative donor...

structure plots of alternative splicing events from .bam, .gtf, and .vcf files. SpliceR An R package for classification of alternative splicing and prediction...

exclusion during splicing. These sites are referred to as exonic splicing enhancers (ESEs), exonic splicing silencers (ESSs), intronic splicing enhancers (ISEs)...

is an Argentine molecular biologist who specializes in alternative ribonucleic acid splicing. During his postdoctoral training with Francisco Baralle...

examples of alternative splicing is in the Drosophila DSCAM gene, which can give rise to approximately 30 thousand distinct alternatively spliced isoforms...

alternative splicing of multiple exons to generate fsTnT variants, two-dimensional gel electrophoresis detected more than 40 different fsTnT splice forms...

alternative splicing compared to genes that code a single isoform. This is because alternatively spliced mRNAs are enriched in METTL3 binding sites. Splicing is...

to a sequence could impact splicing, this process may result in changing the identity of introns and exons; alternatively, the sequence may retain its...

"Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer". Mol. Cell. Biol. 23 (13): 4687–700...

still remains an important challenge. As a consequence, the role of alternative splicing in molecular biology remains largely elusive. Third generation sequencing...

The primary function is regulation of alternative splicing of associated genes. Several alternatively spliced transcript variants have been found for...

of splicing factors. In D. melanogaster, Sxl exerts its effects primarily through post-transcriptional regulation, specifically alternative splicing and...

encodes several distinct DNA ligase species by alternative translation initiation and alternative splicing mechanisms that are described below. Eukaryotic...

alternative splicing, and certain splice variants of neuroligins and neurexins are more selective for one another. Specific pairing of splice variants also...

relevant, alternative splicing and processing noise due to splicing errors. One of the central issues in the field of alternative splicing is working out the...

mRNA. Alternative splicing is a mechanism by which different proteins can be produced from a single gene by means of using alternative splicing sites...

while APH1B is found on chromosome 15q22.2. Both genes exhibit alternative splicing, leading to the generation of multiple transcript variants that enhance...

initiation, polyadenylation and splicing variant data. Alternative Splicing Annotation Project AspicDB RNA splicing Koscielny, Gautier; Le Texier, Vincent;...

are longer than those of high-density arrays and cannot identify alternative splicing events. Spotted arrays use two different fluorophores to label the...

by amyotrophic lateral sclerosis. These studies suggest that such alternative splicing could play a role in the disease and lend themselves to further investigation...

Alternative Splicing Annotation Project (ASAP) in computational biology was a database for alternative splicing data maintained by the University of California...

translation of messenger RNA. Splicing is the process by which non-coding regions of RNA are removed. The number and combination of splicing events varies greatly...