cognate tRNAs to form an aminoacyl-tRNA. In humans, the 20 different types of aa-tRNA are made by the 20 different aminoacyl-tRNA synthetases, one for...
31 KB (3,633 words) - 22:47, 23 May 2025
The aminoacyl-tRNA synthetases catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step reaction. These...
5 KB (585 words) - 15:20, 1 October 2024
Aminoacyl-tRNA synthetases, class II is a family of proteins. These proteins catalyse the attachment of an amino acid to its cognate transfer RNA molecule...
4 KB (472 words) - 15:19, 1 October 2024
covalent attachment to the tRNA 3' end is catalysed by enzymes called aminoacyl tRNA synthetases. During protein synthesis, tRNAs with attached amino acids...
69 KB (8,266 words) - 12:23, 22 June 2025
aminoacyl-tRNA synthetases can distinguish between different tRNAs and this recognition doesn't follow the same pattern. An aminoacyl-tRNA synthetase...
12 KB (1,610 words) - 14:15, 17 March 2025
the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II...
16 KB (1,940 words) - 05:29, 2 June 2025
RARS (gene) (redirect from Arginyl-tRNA synthetase)
tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I...
9 KB (1,090 words) - 05:04, 13 August 2023
WARS (gene) (redirect from Tryptophanyl-tRNA synthetase, cytoplasmic)
Tryptophanyl-tRNA synthetase, cytoplasmic is an aminoacyl-tRNA synthetase enzyme that attaches the amino acid tryptophan to its cognate tRNA. In humans...
9 KB (1,042 words) - 12:13, 30 April 2025
and aminoacyl-tRNA biosynthesis. Phenylalanine-tRNA synthetase (PheRS) is known to be among the most complex enzymes of the aaRS (Aminoacyl-tRNA synthetase)...
5 KB (503 words) - 14:26, 22 September 2024
Methionyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the MARS gene. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs...
6 KB (731 words) - 04:11, 14 October 2022
Isoleucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the IARS1 gene. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA...
6 KB (757 words) - 16:04, 30 January 2024
Translation (biology) (redirect from RNA translation)
where mRNA codons are matched through complementary base pairing to specific tRNA anticodons. Aminoacyl-tRNA synthetases that mispair tRNAs with the...
36 KB (4,225 words) - 02:57, 1 June 2025
cognate tRNA. This enzyme participates in glutamate metabolism and aminoacyl-trna biosynthesis. The human gene for glutaminyl-tRNA synthetase is QARS...
8 KB (775 words) - 23:24, 27 May 2025
of the variant have not been determined. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein...
10 KB (1,158 words) - 17:10, 27 December 2023
Expanded genetic code (section tRNA/synthetase pair)
each amino acid (20 or more synthetases). On the other hand, some bacteria have fewer than 20 aminoacyl tRNA synthetases, and introduce the "missing"...
79 KB (9,144 words) - 21:39, 22 May 2025
carbon-oxygen bonds in tRNA and related compounds. More specifically, it belongs to the family of the aminoacyl-tRNA synthetases. These latter enzymes...
29 KB (3,787 words) - 23:22, 27 March 2024
constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm. Aminoacyl-tRNA synthetases are a class of enzymes...
11 KB (1,264 words) - 22:51, 3 March 2023
isoleucine biosynthesis and aminoacyl-trna biosynthesis. As of late 2007, 10 structures have been solved for this class of enzymes, with PDB accession...
3 KB (304 words) - 17:40, 28 October 2024
mechanisms: Class I aminoacyl-tRNA synthetases (AATRSs): These enzymes are responsible for attaching amino acids to their corresponding tRNAs Nucleotide...
6 KB (668 words) - 17:42, 9 June 2025
of selection of amino acids during protein biosynthesis by the aminoacyl-tRNA synthetases, where he formulated the double-sieve editing mechanism. Fersht...
25 KB (2,314 words) - 21:42, 4 June 2025
Valyl-tRNA synthetase is an enzyme that in humans is encoded by the VARS gene. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their...
7 KB (897 words) - 17:07, 12 May 2024
gene encodes the enzyme glycyl-tRNA synthetase (GlyRS), which belongs to the class II group of aminoacyl-tRNA synthetases. This enzyme is essential in the...
41 KB (4,293 words) - 11:47, 7 June 2025
ribonucleic acid synthetase, and aspartyl ribonucleate synthetase. This enzyme participates in alanine and aspartate metabolism and aminoacyl-trna biosynthesis...
3 KB (241 words) - 14:50, 22 September 2024
and isoleucine biosynthesis and aminoacyl-trna biosynthesis. As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession...
3 KB (254 words) - 15:28, 22 September 2024
mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family...
5 KB (673 words) - 17:40, 3 April 2024
forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-lysine:tRNALys ligase (AMP-forming). Other...
3 KB (284 words) - 14:40, 22 September 2024
one carbon pool by folate, and aminoacyl-tRNA biosynthesis. As of late 2007, two structures have been solved for this class of enzymes, with PDB accession...
2 KB (147 words) - 14:22, 22 September 2024
transfer RNA (tRNA) with a CUA anticodon, and the pylS gene, which encodes a class II aminoacyl-tRNA synthetase that charges the pylT-derived tRNA with pyrrolysine...
28 KB (3,183 words) - 20:49, 3 July 2025
Lysyl-tRNA synthetase is an enzyme that in humans is encoded by the KARS gene. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with...
11 KB (1,417 words) - 03:05, 8 April 2024
leucine-tRNA synthetase, and leucine translase. This enzyme participates in valine, leucine and isoleucine biosynthesis and aminoacyl-trna biosynthesis...
3 KB (292 words) - 15:49, 22 September 2024