azasteroid is a type of steroid derivative which has one of the carbon atoms in the steroid ring system replaced by a nitrogen atom. Two azasteroids,...
3 KB (281 words) - 03:03, 29 May 2024
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
84 KB (8,687 words) - 23:44, 11 July 2025
GF, Rasmusson GH (August 1991). "Topical anti-androgenicity of a new 4-azasteroid in the hamster". Steroids. 56 (8): 428–433. doi:10.1016/0039-128x(91)90031-p...
23 KB (2,061 words) - 06:21, 14 January 2025
prostate. The enzyme is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in 5αR2 activity of the can lead to...
8 KB (1,048 words) - 03:21, 8 November 2023
-4-aza-5α-androst-1-en-3-one, is a synthetic androstane steroid and 4-azasteroid. It is an analogue of androgen steroid hormones like testosterone and...
72 KB (7,420 words) - 17:37, 14 June 2025
rings of the steroids by a heteroatom such as nitrogen thereby forming azasteroids. The receptor is known to consist of two hydrogen bond donors, where...
13 KB (1,661 words) - 08:23, 23 May 2025
candocuronium iodide (INN) (chandonium iodide, HS-310), which is a synthetic azasteroid. A new neuromuscular blocker, initially named as Chandonium Iodide, was...
11 KB (1,115 words) - 22:17, 17 July 2025
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
31 KB (3,874 words) - 08:10, 13 July 2025
metabolic compounds, including walleminol, walleminone, wallemia A and C, and azasteroid UCA1064-B. A comprehensive research on other species of the class discovered...
8 KB (851 words) - 15:35, 28 October 2024
rost-1-ene-17β-carboxamide, is a synthetic androstane steroid and a 4-azasteroid. It is an analogue of finasteride in which the tert-butyl amide moiety...
50 KB (5,010 words) - 09:58, 13 July 2025
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
1 KB (89 words) - 18:52, 13 February 2025
prostate and in prostate cancer cells. Structurally, it is specifically a 4-azasteroid derivative. MK-4541 was first described in the scientific literature by...
9 KB (707 words) - 04:06, 15 July 2025
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
9 KB (682 words) - 00:01, 28 May 2025
loss, hirsutism, feminizing HRT ATC code G04CB Biological target 5α-Reductase (1, 2, 3) Chemical class Steroids; Azasteroids Legal status In Wikidata...
31 KB (3,434 words) - 14:06, 12 December 2024
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
4 KB (387 words) - 01:53, 8 June 2025
more advanced version of the related compound TFM-4AS-1. MK-0773 is a 4-azasteroid and a potent and selective agonist of the androgen receptor (AR). It binds...
11 KB (965 words) - 15:54, 28 October 2024
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
3 KB (109 words) - 09:15, 13 December 2023
design of candocuronium belongs to a series of mono- and bis-quaternary azasteroids. This approach used the rigid steroid skeleton as a spacer to hold two...
13 KB (1,248 words) - 06:08, 16 July 2025
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
5 KB (432 words) - 17:41, 24 April 2025
levels by a maximum of approximately 50% in men. MK-434 is a synthetic 4-azasteroid and is structurally related to other 5α-reductase inhibitors like finasteride...
4 KB (260 words) - 00:30, 14 March 2022
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
3 KB (330 words) - 19:09, 2 February 2023
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
2 KB (83 words) - 17:35, 25 April 2023
endogenous androgens in the prostate gland. Structurally, TFM-4AS-1 is a 4-azasteroid. A structurally related and more advanced version of TFM-4AS-1, MK-0773...
5 KB (357 words) - 15:53, 5 February 2025
inhibitor which was first reported in 1994 and was never marketed. It is a 4-azasteroid and a potent and selective inhibitor of 5α-reductase type I and shows...
10 KB (956 words) - 20:13, 24 May 2025
II (IC50 = 6 and 10 nM, respectively). Structurally, Cl-4AS-1 is a 4-azasteroid. MK-0773 MK-4541 TFM-4AS-1 YK-11 Tolman RL, Sahoo SP, Bakshi RK, Gratale...
4 KB (220 words) - 18:50, 16 January 2025
Nett TM (February 1995). "Comparison of the effects of new specific azasteroid inhibitors of steroid 5 alpha-reductase on canine hyperplastic prostate:...
27 KB (3,061 words) - 03:59, 18 July 2025
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
4 KB (377 words) - 20:32, 9 February 2024
the infrastructure of solanum alkaloids, accomplished the synthesis of azasteroids using a new pathway, and developed a protocol for linking aromatic rings...
18 KB (1,572 words) - 17:22, 8 June 2024
C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements replaced Azasteroid...
1 KB (118 words) - 13:00, 29 June 2025
metabolic compounds like walleminol, walleminone, wallemia A and C, and azasteroid UCA1064-B A newly conducted study also observes a light yellow oil-like...
23 KB (2,677 words) - 01:17, 7 September 2024