The azide-alkyne Huisgen cycloaddition is a 1,3-dipolar cycloaddition between an azide and a terminal or internal alkyne to give a 1,2,3-triazole. Rolf...
21 KB (2,639 words) - 20:31, 22 July 2024
the azide alkyne Huisgen cycloaddition, organic azides react as 1,3-dipoles, reacting with alkynes to give substituted 1,2,3-triazoles. Some azide reactions...
28 KB (2,857 words) - 13:45, 22 May 2025
describe the 1,3-dipolar cycloaddition between an organic azide and an alkyne to generate 1,2,3-triazole). 1,3-dipolar cycloaddition is an important route...
65 KB (6,396 words) - 07:16, 24 May 2025
undergo cyclization, e.g. azide alkyne Huisgen cycloaddition to give triazoles. Cycloaddition processes involving alkynes are often catalyzed by metals...
24 KB (3,193 words) - 03:32, 16 June 2025
= +2.71 V) The azide functional group is commonly utilized in click chemistry through copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions...
19 KB (2,194 words) - 08:17, 24 May 2025
chemistry is a bioorthogonal reaction as a variant of an azide-alkyne Huisgen cycloaddition. By eliminating cytotoxic copper catalysts, the reaction proceeds...
7 KB (878 words) - 17:17, 28 May 2025
cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react...
10 KB (1,024 words) - 23:01, 1 May 2025
developed by Carolyn Bertozzi as an activated variant of an azide alkyne Huisgen cycloaddition, based on the work by Karl Barry Sharpless et al. Unlike CuAAC...
44 KB (5,098 words) - 08:36, 16 March 2025
under mild conditions; the most successful example is the azide alkyne Huisgen cycloaddition to form 1,2,3-triazoles. As of 2024[update], Sharpless has...
13 KB (1,067 words) - 02:11, 27 March 2025
(2002). "A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective "Ligation" of Azides and Terminal Alkynes". Angewandte Chemie International...
48 KB (5,449 words) - 15:24, 15 June 2025
the Banert cascade or the azide alkyne Huisgen cycloaddition in which an azide and an alkyne undergo a 1,3-dipolar cycloaddition reaction. Under thermal...
6 KB (482 words) - 04:50, 5 February 2025
Cyclooctyne, the smallest isolable cycloalkyne, is able to undergo azide-alkyne Huisgen cycloaddition under mild, physiological conditions in the absence of a copper(I)...
14 KB (1,564 words) - 16:10, 27 May 2025
Bioconjugation (section Huisgen cyclization of azides)
ligation with organic azides, copper-catalyzed Huisgen cycloaddition of azides, and strain promoted Huisgen cycloaddition of azides. The nucleophilic lysine...
43 KB (4,669 words) - 00:31, 25 May 2025
reaction Cycloaddition 1,3-Dipolar cycloaddition Azide-alkyne Huisgen cycloaddition Diels–Alder reaction Nitrone-olefin (3+2) cycloaddition Staudinger...
8 KB (574 words) - 12:46, 7 March 2025
group; which is produced by the 1,3-dipolar cycloaddition, also called the azide-alkyne Huisgen cycloaddition. These polymers can take on the form of a...
28 KB (3,715 words) - 07:02, 8 September 2024
allows for quantitative, regioselective formal Huisgen 1,3-dipolar cycloadditions between alkynes and azides, in a variety of aqueous and organic solvents...
4 KB (279 words) - 02:00, 22 August 2022
structures. Named ring forming reactions include (not exhaustive): Azide-alkyne Huisgen cycloaddition Bischler–Napieralski reaction Bucherer carbazole synthesis...
2 KB (262 words) - 09:29, 18 November 2024
(2002). "A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective "Ligation" of Azides and Terminal Alkynes". Angewandte Chemie International...
13 KB (839 words) - 21:44, 21 October 2023
or an affinity label such as biotin or an alkyne or azide for use with the Huisgen 1,3-dipolar cycloaddition (also known as click chemistry). A major advantage...
6 KB (589 words) - 20:38, 27 May 2025
and psychotropic drug efavirenz. It can also be used in the azide-alkyne Huisgen cycloaddition. "Cyclopropylacetylene : density 0.781 g/mL at 25 °C". Sigmaaldrich...
4 KB (274 words) - 08:14, 28 May 2025
Huisgen (1920–2020) Germany "for development of the 1,3-Dipolar cycloaddition Reaction (Huisgen reaction) and the variant Copper(I)-catalyzed Azide-Alkyne...
28 KB (359 words) - 04:37, 12 April 2025
1-Decyne (category Alkynes)
(2002). "A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective "Ligation" of Azides and Terminal Alkynes". Angewandte Chemie International...
4 KB (237 words) - 06:07, 28 May 2025
Hosomi–Sakurai reaction Houben–Fischer synthesis Hudlicky fluorination Huisgen cycloaddition Hunsdiecker reaction, Hunsdiecker–Borodin reaction Hurd-Mori 1,2...
37 KB (3,428 words) - 16:27, 11 November 2024
Chemistry Approach to Tetrazoles by Huisgen 1,3-Dipolar Cycloaddition: Synthesis of 5-Acyltetrazoles from Azides and Acyl Cyanides". Angewandte Chemie...
3 KB (408 words) - 08:42, 9 October 2022
or an affinity label such as biotin or an alkyne or azide for use with the Huisgen 1,3-dipolar cycloaddition (also known as click chemistry). Suicide inhibition...
8 KB (1,176 words) - 14:14, 19 March 2023
chelation-assisted copper-catalyzed azide-alkyne cycloaddition (CuAAC) (refer to Azide-alkyne Huisgen cycloaddition). Two other versions of PRIME labeling...
7 KB (824 words) - 02:09, 3 December 2024
triazole molecule. Clicked peptide polymers are prepared by the azide-alkyne Huisgen cycloaddition also called the click reaction; which is commonly used in...
4 KB (421 words) - 09:43, 24 August 2023
terminal alkyne, and of TRAP with three linkers bearing terminal azides. These components are assembled by means of copper(I) catalyzed alkyne-azide cycloaddition...
39 KB (3,472 words) - 03:17, 18 June 2025