C4b-binding protein (C4BP) is a protein complex involved in the complement system where it acts as inhibitor. C4BP has an octopus-like structure with...

complement protein C4b-binding protein (C4BP). In humans, protein S is encoded by the PROS1 gene. Protein S plays a role in coagulation. Protein S is named...

Lipopolysaccharide-binding protein C4b-binding protein Rap GTP-binding protein Calmodulin-binding proteins Iron-binding proteins Thyroxine-binding proteins Folate-binding...

cofactor for the enzyme C3bINA. C4b-binding protein inhibits the haemolytic function of cell-bound C4b. C4b-binding protein and C3b inactivator control the...

Mannose-binding lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as...

C4B genes usually in tandem RCCX cassettes with copy number variation, that somewhat parallels variation in the levels of their respective proteins within...

activated protein C (APC). Protein C is activated in a sequence that starts with Protein C and thrombin binding to a cell surface protein thrombomodulin...

proteins (C3b and C5) to avoid opsonisation. It can also recruit complement regulators such as Factor H, C4b-binding protein, factor H-like binding protein...

Borrelia recurrentis and B. duttonii acquire complement regulators C4b-binding protein and factor H". Infection and Immunity. 74 (7): 4157–63. doi:10.1128/IAI...

also formed by the classical pathway when C3b binds C4b and C2b. C5a is an important chemotactic protein, helping recruit inflammatory cells. C3a is the precursor...

also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein of the complement...

physical inactivity. Protein S circulates in human plasma in two forms: approximately 60 percent is bound to complement component C4b β-chain while the remaining...

to the pathogens surface. Surface-bound C4b acts as a receptor for the binding of C2. The binding of C2 and C4b results in C2 being cleaved by C1s into...

Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene...

regulators Membrane Cofactor Protein, MCP (CD46) Decay Accelerating Factor, DAF (CD55) Protectin (CD59) Complement C3b/C4b Receptor 1, CR1 (CD35) Complement...

C2 into C4a, C4b, C2a, and C2b. In f, two smaller MBL-associated proteins (MAps) are found in complex with MBL. MBL-associated protein of 19 kDa (MAp19)...

adaptive immunity may even be required. Complement proteins involved in innate opsonization include C4b, C3b and iC3b. In the alternative pathway of complement...

"Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein". FEBS Letters. 271 (1–2): 131–6. doi:10.1016/0014-5793(90)80389-Z...

complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein". Proceedings of the National Academy of Sciences...

demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution". The Journal of Experimental Medicine. 146...

DAF, is a protein that, in humans, is encoded by the CD55 gene. DAF regulates the complement system on the cell surface. It recognizes C4b and C3b fragments...

complex III (MHC class III) close to the Complement component 4 genes C4A and C4B, the Tenascin X gene TNXB and STK19. MHC class III is the most gene-dense...

blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes the basic form of complement...

complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. The protein encoded by this gene may be involved...

complement proteins, C4b, C2a produced by cleavage mediated by C1 complex, and C3b produced by cleavage mediated by the classical pathway C3 convertase (C4bC2a)...

C4 and C2 forming a C4bC2b complex that covalently bonds to the surface of the microbe and functions as a C3 convertase, binding and cleaving C3 into...

complement components C4 and C2 into C4a, C4b, C2a, and C2b. MASP1 (protein) Mannan-binding lectin Mannan-binding lectin pathway (lectin pathway) GRCh38:...

genes ,C4A and C4B. (The C4A and C4B genes code respectively for complement component A and complement component B proteins. These two proteins combine to...

C1 inhibitor, C4b-binding protein, factor I, S protein or clusterin, the membrane-bound inhibitors are CR1, membrane cofactor protein (MCF), decay accelerating...

Active C1s splits C4 and then C2, producing C4a, C4b, C2a and C2b. The classical pathway C3-convertase (C4bC2b complex) is created, which promotes cleavage...