Integrin alpha M (redirect from Cd11b)
ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). The second chain of αMβ2 is the common integrin β2 subunit known as CD18...
15 KB (1,716 words) - 17:02, 7 November 2023
macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2). The integrin α chain is noncovalently...
9 KB (1,147 words) - 01:46, 25 November 2024
circulating cells which are CD11b (also known as integrin alpha) expressive are reduced in susceptible individuals. CD11b has a vital role in activation...
16 KB (1,746 words) - 18:24, 9 May 2025
cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into...
19 KB (2,409 words) - 16:20, 11 December 2023
Lymphocyte Function-associated Antigen 1, also called αLβ2 integrin Mac1 (CD11b/CD18) present on macrophages that is also called Macrophage-1 antigen (CR3)...
1,012 bytes (87 words) - 01:41, 12 July 2023
b) and are located in the β2 integrin. HNA-4 is located on the αM chain (CD11b) and HNA-5 is located on the αL integrin unit (CD11a). Two functionally...
55 KB (5,866 words) - 12:36, 23 May 2025
with RAW cells for 45 minutes at 37°C. RAW cells were labelled with anti-CD11b-APC (cyan). The RAW cell has extensively trogocytosed both RTX and PKH26...
19 KB (2,144 words) - 20:23, 18 April 2025
groups CD45+ Granulocyte CD45+, CD11b, CD15+, CD24+, CD114+, CD182+ Monocyte CD4, CD45+, CD14+, CD114+, CD11a, CD11b, CD91+, CD16+ T lymphocyte CD45+...
14 KB (1,446 words) - 09:33, 19 February 2025
CD9, CD27 with low to negligible levels of secreted-IgD, CD23, CD5, and CD11b that help to distinguish them phenotypically from follicular (FO) B cells...
12 KB (1,506 words) - 10:52, 17 July 2024
patches, and attracts dendritic cells that possess the cell surface molecule CD11b and the chemokine receptor CCR1. CCL9 can activate osteoclasts through its...
4 KB (600 words) - 02:51, 25 December 2023
reactions identified as "severe" were associated with the up-regulation of CD11b on CD4+ and CD8+ T cells, suggesting a basis for further research into the...
5 KB (494 words) - 18:42, 28 May 2025
alpha-helices. 3D structures have been determined for the I-domains of integrins CD11b (with bound magnesium) and CD11a (with bound manganese). The domain adopts...
8 KB (791 words) - 10:27, 20 January 2025
immunohistochemical staining by their specific expression of proteins such as CD14, CD40, CD11b, CD64, F4/80 (mice)/EMR1 (human), lysozyme M, MAC-1/MAC-3 and CD68. Macrophages...
96 KB (10,500 words) - 04:31, 26 May 2025
levels of MRP-8/14 in type 1 diabetes induce an increased expression of CD11b and an enhanced adhesion of circulating monocytes to fibronectin". Diabetes...
22 KB (2,428 words) - 06:39, 2 June 2025
B3 (CVB3) causes immune cells CD11b+ (present on macrophages) to stimulate inflammatory infiltration. Functionally, CD11b+ regulates leukocyte adhesion...
28 KB (3,185 words) - 05:30, 2 June 2025
take the stage A small CD11b+ human B1 cell subpopulation stimulates T cells and is expanded in lupus. Human “orchestrator” CD11b+ B1 cells spontaneously...
22 KB (2,195 words) - 07:03, 30 May 2025
characteristically express high levels of surface IgM (sIgM), demonstrable CD11b, and low levels of surface IgD (sIgD), CD21, CD23, and the B cell isoform...
11 KB (1,484 words) - 15:52, 8 May 2024
Immunophenotypically, M5-AML variably express myeloid (CD13, CD33) and monocytic (CD11b, CD11c) markers. Cells may aberrantly express B-cell marker CD20 and the...
6 KB (605 words) - 20:46, 23 July 2024
antigen or "integrin αMβ2" 170,000 α chain + common 95,000 β chain iC3b CD11b+CD18 FDC, Mac, M0, PMN Leukocyte adherence, phagocytosis of iC3b-bound particles...
6 KB (376 words) - 06:42, 5 March 2024
ITGA11 ITGA11 HsT18964 ITGAD CD11D FLJ39841 ITGAE CD103 HUMINAE ITGAL CD11a LFA1A ITGAM CD11b MAC-1 ITGAV CD51 VNRA, MSK8 ITGA2B CD41 GPIIb ITGAX CD11c...
36 KB (3,928 words) - 22:54, 6 February 2025
FCN2 FCN3 Complement receptor CR1 (CD35) CR2 (CD21) CR3 - Heterodimer: CD11b / CD18 CR4 - Heterodimer: CD11c / CD18 CRIg (Complement receptor of the...
38 KB (2,656 words) - 20:26, 6 November 2024
activated. It has been shown to interact with the leukocyte integrin Mac1 (CD11b/CD18) and may play a role in leukocyte homing and recruitment. Role of Thy-1...
25 KB (3,401 words) - 16:19, 13 October 2024
binds the complement receptor 3 (CR3), the αMβ2 integrin known also as CD11b/CD18 or Mac-1. Then, the toxin translocates its AC enzyme domain across...
6 KB (714 words) - 19:23, 20 May 2024
of anti-PD1 antibody over single-agent treatment. SLR14 was absorbed by CD11b+ myeloid cells in the tumor microenvironment. Genes associated with immune...
83 KB (9,543 words) - 01:52, 1 June 2025
resulting in different integrins. The known binding partners of CD18 are CD11a, CD11b, CD11c and CD11d. Binding of CD18 and CD11a results in the formation of...
11 KB (1,299 words) - 10:15, 11 December 2023
2003). "Loss of S100A9 (MRP14) Results in Reduced Interleukin-8-Induced CD11b Surface Expression, a Polarized Microfilament System, and Diminished Responsiveness...
16 KB (2,090 words) - 18:36, 9 January 2024
common feature in biopsies. The phenotypical characteristics of CMML are; CD11b, CD11c, CD14, CD33, CD45 and CD64 seen in 100% of cases; CD13 found in 95%...
25 KB (2,930 words) - 20:21, 29 May 2025
collagen in the basement membrane and is essential for CD11b+ myeloid cell recruitment. CD11b+ cells in turn adhere to crosslinked collagen and produce...
25 KB (3,018 words) - 20:42, 22 May 2025
CD135−, Slamf1/CD150+, Mac-1 (CD11b)lo Early MPP: CD34+, SCA-1+, Thy1.1−, C-kit+, lin−, CD135+, Slamf1/CD150−, Mac-1 (CD11b)lo, CD4lo Late MPP: CD34+, SCA-1+...
12 KB (1,400 words) - 04:38, 30 December 2024
on their surface CD73, CD90 and CD105, while lacking the expression of CD11b, CD14, CD19, CD34, CD45, CD79a and HLA-DR surface markers. A study in Science...
47 KB (5,353 words) - 21:29, 29 May 2025