• A carboxylate transporter is a membrane transport protein that transports carboxylate. They are responsible for the reabsorption of filtered carboxylate...
    1,017 bytes (91 words) - 21:18, 1 February 2024
  • Thumbnail for Serotonin transporter
    The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that...
    31 KB (3,442 words) - 04:44, 15 July 2025
  • Thumbnail for Dopamine transporter
    The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded for in humans by the SLC6A3 gene (also...
    84 KB (9,214 words) - 21:49, 9 July 2025
  • a carboxylate or sulfonate group. They are unique in that they utilize a substrate binding protein (SBP) in combination with a secondary transporter. TRAP...
    13 KB (1,452 words) - 09:17, 18 February 2025
  • Thumbnail for Renal physiology
    reabsorption is indirect. For example, bicarbonate (HCO3−) does not have a transporter, so its reabsorption involves a series of reactions in the tubule lumen...
    22 KB (1,917 words) - 16:47, 9 October 2024
  • SLC12A8, SLC12A9) Na+-sulfate/carboxylate cotransporter (SLC13A1, SLC13A2, SLC13A3, SLC13A4, SLC13A5) urea transporter (SLC14A1, SLC14A2) proton oligopeptide...
    35 KB (3,407 words) - 13:57, 6 June 2025
  • monocarboxylate transporters, or MCTs, are a family of proton-linked plasma membrane transporters that carry molecules having one carboxylate group (monocarboxylates)...
    7 KB (757 words) - 09:22, 19 February 2025
  • Thumbnail for Norepinephrine transporter
    The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family...
    33 KB (3,491 words) - 04:31, 15 July 2025
  • Glutamate transporters are a family of neurotransmitter transporter proteins that move glutamate – the principal excitatory neurotransmitter – across...
    24 KB (2,828 words) - 15:14, 24 September 2023
  • atypical SLCs are secondary active or facilitative transporters in humans. Collectively membrane transporters and channels are known as the transportome. Transportomes...
    26 KB (2,656 words) - 14:08, 8 March 2025
  • Thumbnail for Glucose transporter
    Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane, a process known as facilitated...
    16 KB (1,327 words) - 21:12, 2 October 2024
  • Thumbnail for Vesicular monoamine transporter 2
    carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2 gene...
    29 KB (3,347 words) - 15:17, 4 July 2025
  • Thumbnail for 1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine
    4-Fluoropethidine Allylprodine JZ-IV-10 N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate WY-46824 US 6180648, Kozikowski AP, Araldi GL, "Analogs of cocaine",...
    4 KB (348 words) - 22:13, 11 January 2025
  • Thumbnail for Monocarboxylate transporter 8
    Monocarboxylate transporter 8 (MCT8) is an active transporter protein that in humans is encoded by the SLC16A2 gene. MCT8 actively transports a variety...
    13 KB (1,394 words) - 06:34, 19 July 2025
  • Thumbnail for Cystine/glutamate transporter
    Cystine/glutamate transporter is an antiporter that in humans is encoded by the SLC7A11 gene. The SLC7A11 gene encodes a sodium-independent cystine-glutamate...
    26 KB (3,291 words) - 05:33, 19 July 2025
  • composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1). LAT1 is a heterodimeric membrane transport protein that preferentially...
    4 KB (356 words) - 21:46, 15 June 2025
  • The Transporter Classification Database (or TCDB) is an International Union of Biochemistry and Molecular Biology (IUBMB)-approved classification system...
    38 KB (5,159 words) - 17:34, 13 June 2025
  • Thumbnail for Equilibrative nucleoside transporter 1
    Equilibrative nucleoside transporter 1 (ENT1) is a protein that in humans is encoded by the SLC29A1 gene. Multiple alternatively spliced variants, encoding...
    11 KB (1,274 words) - 16:29, 17 July 2025
  • Thumbnail for Excitatory amino acid transporter 2
    Excitatory amino acid transporter 2 (EAAT2) also known as solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1) is a protein that...
    18 KB (2,251 words) - 17:16, 16 July 2025
  • glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa (enterocytes) of...
    16 KB (1,628 words) - 18:49, 17 November 2024
  • Thumbnail for GABA transporter type 1
    GABA transporter 1 (GAT1) also known as sodium- and chloride-dependent GABA transporter 1 is a protein that in humans is encoded by the SLC6A1 gene and...
    19 KB (2,156 words) - 04:11, 15 July 2025
  • Thumbnail for Losartan
    Boyle TP, Graham RM, Husain A, et al. (February 1995). "Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by...
    34 KB (2,727 words) - 21:23, 29 May 2025
  • Thumbnail for Ion transporter
    In biology, an ion transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different...
    17 KB (2,043 words) - 12:51, 15 July 2025
  • Thumbnail for JZ-IV-10
    carboxylate Nocaine WO 2005041875, Kozikowski, Alan P. & Zhou, Jia, "Dopamine-, norepinephrine- and serotonin- transporter- selective heterocyclic...
    4 KB (193 words) - 09:57, 20 September 2024
  • oil) Monocarboxylate transporters, a family of proton-linked plasma membrane transporters that carry molecules having one carboxylate group (monocarboxylates)...
    3 KB (379 words) - 15:52, 3 September 2023
  • Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons. Their primary function is to carry...
    9 KB (988 words) - 08:33, 25 May 2025
  • Thumbnail for 3-Bromomethylphenidate
    3-Bromomethylphenidate (category Carboxylate esters)
    as a designer drug. It showed the most potent binding to the dopamine transporter of a series of ring-substituted methylphenidate derivatives, and produced...
    3 KB (188 words) - 18:21, 15 January 2025
  • Thumbnail for Monocarboxylate transporter 1
    Monocarboxylate transporter 1 is a ubiquitous protein that in humans is encoded by the SLC16A1 gene (also known as MCT1). It is a proton coupled monocarboxylate...
    12 KB (1,379 words) - 06:34, 19 July 2025
  • Thumbnail for Vesicular glutamate transporter 1
    Vesicular glutamate transporter 1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene. The protein encoded by this gene is a vesicle-bound...
    5 KB (601 words) - 18:47, 17 July 2025
  • A urea transporter is a membrane transport protein, transporting urea. Humans and other mammals have two types of urea transport proteins, UT-A and UT-B...
    6 KB (659 words) - 23:06, 26 May 2025