• Thumbnail for Chenodeoxycholic acid
    Chenodeoxycholic acid (CDCA; also known as chenodesoxycholic acid, chenocholic acid and 3α,7α-dihydroxy-5β-cholan-24-oic acid) is a bile acid. Salts of...
    18 KB (1,357 words) - 05:17, 17 April 2025
  • cholic acid) and taurochenodeoxycholic acid and glycochenodeoxycholic acid (derivatives of chenodeoxycholic acid) are the major bile salts. The salts of...
    31 KB (3,853 words) - 04:46, 9 April 2025
  • Thumbnail for Cholic acid
    substance. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver...
    11 KB (926 words) - 14:26, 24 March 2025
  • Thumbnail for Ursodeoxycholic acid
    which is less frequent than with chenodeoxycholic acid therapy. Bacterial conversion of UDCA to chenodeoxycholic acid may be the mechanism for this side...
    29 KB (2,908 words) - 14:50, 26 May 2025
  • Thumbnail for Obeticholic acid
    acid (OCA), sold under the brand name Ocaliva, is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid...
    21 KB (1,978 words) - 03:13, 7 March 2025
  • Thumbnail for Deoxycholic acid
    bile acids secreted by the liver are cholic acid and chenodeoxycholic acid. Bacteria metabolize chenodeoxycholic acid into the secondary bile acid lithocholic...
    34 KB (3,039 words) - 00:27, 25 March 2025
  • Thumbnail for Bile
    concentration of certain naturally occurring bile acids, such as chenodeoxycholic acid and ursodeoxycholic acid. On an empty stomach – after repeated vomiting...
    19 KB (2,246 words) - 20:32, 23 May 2025
  • Thumbnail for Lithocholic acid
    for absorption. Bacterial action in the colon produces LCA from chenodeoxycholic acid by reduction of the hydroxyl functional group at carbon-7 in the...
    10 KB (806 words) - 17:16, 20 May 2025
  • Thumbnail for Gallstone
    £1000 less per patient). The medications ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA) have been used in treatment to dissolve gallstones...
    53 KB (4,879 words) - 20:43, 22 May 2025
  • Thumbnail for Cerebrotendinous xanthomatosis
    The CYP27A1 gene, responsible for bile acid production, is mutated, reducing chenodeoxycholic acid and cholic acid, leading to increased synthesis of...
    23 KB (2,260 words) - 16:37, 30 March 2025
  • Thumbnail for Glycochenodeoxycholic acid
    Glycochenodeoxycholic acid is a bile salt formed in the liver from chenodeoxycholic acid and glycine, usually found as the sodium salt. It acts as a detergent...
    4 KB (338 words) - 13:11, 21 April 2025
  • Thumbnail for Hyocholic acid
    for the 6-hydroxylation reaction of chenodeoxycholic acid in the pig is the cytochrome P450 CYP4A21. Hyocholic acid can be found in humans with cholestasis...
    5 KB (482 words) - 11:05, 15 January 2025
  • Thumbnail for Taurolithocholic acid
    Taurolithocholic acid is a bile acid. More than 50 types of secondary bile acids produced by microbes from the primary bile acids (cholic acid and chenodeoxycholic acid...
    3 KB (89 words) - 04:28, 28 April 2025
  • Thumbnail for Esophageal cancer
    adenocarcinoma. Bile reflux containing unconjugated bile acids, including deoxycholic acid and chenodeoxycholic acid, appears to contribute to esophageal adenocarcinoma...
    87 KB (8,587 words) - 06:19, 23 May 2025
  • Charcocaps chaulmosulfone (INN) Chealamide Chemet Chenix Chenodal chenodeoxycholic acid (INN) Cheracol Cheratussin DAC CHG Scrub Chibroxin chiniofon (INN)...
    6 KB (361 words) - 04:38, 22 February 2025
  • may refer to: Chenodeoxycholic acid, a bile acid Deoxycholic acid, a bile acid Hyodeoxycholic acid, a bile acid Ursodiol, a bile acid This set index...
    362 bytes (71 words) - 13:31, 25 September 2024
  • Thumbnail for Zellweger syndrome
    Bile acid synthesis is defective due to lack of side chain modifications; for example, the last steps in the synthesis of chenodeoxycholic acid and cholic...
    14 KB (1,375 words) - 20:28, 7 May 2025
  • Thumbnail for Hyodeoxycholic acid
    tweezer based on a hyodeoxycholic acid showed a high selectivity the towards the fluorine radical. Chenodeoxycholic acid for a similar molecular tweezer...
    12 KB (1,299 words) - 00:51, 12 July 2024
  • forms, α- and β-muricholic acids, differ from the primary bile acids found in humans, cholic acid and chenodeoxycholic acid, by both having a hydroxyl...
    4 KB (441 words) - 14:05, 30 December 2024
  • Thumbnail for Taurochenodeoxycholic acid
    Taurochenodeoxycholic acid is a bile acid formed in the liver of most species, including humans, by conjugation of chenodeoxycholic acid with taurine. It is...
    5 KB (418 words) - 22:40, 10 May 2025
  • acids, such as cholic acid and chenodeoxycholic acid, after which gut commensals like C. scindens convert them into unconjugated secondary bile acids...
    19 KB (2,011 words) - 16:27, 11 February 2025
  • Thumbnail for Inflammatory bowel disease
    cholic acid and chenodeoxycholic acid (and their conjugated forms), and a decreased abundance of secondary bile acids such as lithocholic acid and deoxycholic...
    103 KB (11,366 words) - 23:41, 25 May 2025
  • Thumbnail for Farnesoid X receptor
    expressed at high levels in the liver and intestine. Chenodeoxycholic acid and other bile acids are natural ligands for FXR. Similar to other nuclear...
    18 KB (2,072 words) - 23:27, 23 April 2025
  • Thumbnail for Ursodoxicoltaurine
    Bear bile contains several bile acids including taurochenodeoxycholic acid, ursodeoxycholic acid, and chenodeoxycholic acid. UDCA and its taurine conjugates...
    16 KB (1,569 words) - 20:20, 11 October 2024
  • Thumbnail for Gut microbiota
    and chenodeoxycholic acid (CDCA) into secondary bile acids (BAs) lithocholic acid (LCA) and deoxy cholic acid (DCA) respectively. Primary bile acids which...
    114 KB (11,823 words) - 14:53, 24 May 2025
  • Thumbnail for Ivermectin
    1038/ncomms2924. PMID 23728580. Kim SG, Kim BK, Kim K, Fang S (December 2016). "Bile Acid Nuclear Receptor Farnesoid X Receptor: Therapeutic Target for Nonalcoholic...
    76 KB (7,544 words) - 05:15, 26 May 2025
  • Thumbnail for 2,3,7,8-Tetrachlorodibenzofuran
    taurochenodeoxycholic acid, tauromuricholic acid, lithocholic acid, chenodeoxycholic acid, taurolithocholic acid, and an abundance of bile acids and salts.[citation needed]...
    9 KB (1,062 words) - 19:46, 5 May 2025
  • Thumbnail for Enterohepatic circulation
    Hepatocytes metabolize cholesterol to cholic acid and chenodeoxycholic acid. These lipid-soluble bile acids are conjugated (reversibly attached) mainly...
    6 KB (770 words) - 10:04, 13 September 2024
  • Thumbnail for Cholestasis
    and secondary bile acids may lead to PSC via the gut-liver axis. The primary bile acids cholic acid (CA) and chenodeoxycholic acid (CDCA) are synthesized...
    113 KB (12,756 words) - 20:36, 22 May 2025
  • Thumbnail for Gastrointestinal cancer
    and found that higher fecal concentrations of the bile acids cholic acid and chenodeoxycholic acid are associated with a high risk and higher incidence...
    28 KB (3,243 words) - 06:45, 22 March 2025