of trans-NATs that can target multiple transcripts with a few mismatches. Cis-natural antisense transcripts (cis-NATs) on the other hand are transcribed...

Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded...

J. K. (2005). "Endogenous siRNAs Derived from a Pair of Natural cis-Antisense Transcripts Regulate Salt Tolerance in Arabidopsis". Cell. 123 (7): 1279–1291...

PMID 12020814. Brantl S (2007). "Regulatory mechanisms employed by cis-encoded antisense RNAs". Curr. Opin. Microbiol. 10 (2): 102–9. doi:10.1016/j.mib.2007...

name for the antisense DNA strand that is transcribed as part of a larger transcript called LNCAT (large non-coding antisense transcript) at the Ube3a...

process endogenous sources as double-stranded RNAs derived of cis-natural antisense transcripts, generating 22nt short interfering RNA (natsi-RNAs); however...

1984, the first natural anti-sRNA was only discovered in 2014 in an Escherichia coli model. The initial characterization of antisense small RNA within...

of transcripts that do not overlap protein-coding genes. Long non-coding RNAs include intergenic lincRNAs, intronic ncRNAs, and sense and antisense lncRNAs...

one of the two DNA strands serves as a template for transcription. The antisense strand of DNA is read by RNA polymerase from the 3' end to the 5' end...

which causes cell death. An unstable antisense RNA regulator (Rd1D) blocks the translation of the LdrD transcript. A mok homologue which overlaps each...

or may not be stand-alone RNA transcripts. This implies that fRNA (such as riboswitches, SECIS elements, and other cis-regulatory regions) is not ncRNA...

known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vector...

the same way as DNA; an example is an mRNA transcript pairing with an antisense version of the same transcript, which effectively silences the gene from...

There are several methods by which this is achieved. One strategy uses antisense specific to the target gene to disrupt the transcription of the faulty...

use, some biologists have used a broader definition that includes other cis-regulatory RNAs. However, this article will discuss only metabolite-binding...

approaches to modulate RNA levels as a therapeutics include the use of antisense oligonucleotides, including for neurodevelopment diseases associated with...

immunoprecipitation (HITS-CLIP) data . CDR1as/CiRS-7 is encoded in the genome antisense to the human CDR1 (gene) locus (hence the name CDR1as), and targets miR-7...

remains unclear whether TERRA transcripts remain tethered to the telomeres from which they are transcribed, acting in cis, or whether they may move from...

encoded. Contrast cis-acting. transcribed spacer A spacer sequence that is transcribed and thus included in the primary ribosomal RNA transcript (as opposed...

first discovered as a TPA-activated transcription factor that bound to a cis-regulatory element of the human metallothionein IIa (hMTIIa) promoter and...

8) code for the mature protein (Figure 1). Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. The...

thought that no genes are actively expressed. Many noncoding and natural antisense RNA have been identified using tiling arrays. Methyl-DNA immunoprecipitation...

corresponding genes, but there has been evidence of LTRs acting in the antisense direction (3' to 5') and as a bidirectional promoter for neighboring genes...

spliceosome and many small bacterial RNAs regulate gene expression by antisense interactions E.g. GcvB, OxyS and RyhB. The below table includes interactions...

Alagu J, Kaneko Y, Kato M, Tanaka Y, et al. (January 2014). "NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β...