• Thumbnail for Complement deficiency
    Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins. Because of redundancies in...
    15 KB (1,248 words) - 18:12, 28 January 2025
  • Thumbnail for Complement 3 deficiency
    Complement 3 deficiency is a genetic condition affecting complement component 3 (C3). People can suffer from either primary or secondary C3 deficiency...
    8 KB (828 words) - 23:36, 24 September 2024
  • Thumbnail for Terminal complement pathway deficiency
    Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC). It involves deficiencies of C5, C6...
    3 KB (247 words) - 23:27, 7 March 2025
  • Thumbnail for Complement system
    The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies...
    43 KB (5,123 words) - 06:04, 18 June 2025
  • Thumbnail for Complement 2 deficiency
    Complement 2 deficiency is a type of complement deficiency caused by any one of several different alterations in the structure of complement component...
    11 KB (929 words) - 22:53, 19 June 2025
  • Asplenia, where there is no function of the spleen Complement deficiency is where the function of the complement system is deficient In reality, immunodeficiency...
    28 KB (2,595 words) - 07:24, 9 June 2025
  • Complement 4 deficiency is a genetic condition affecting complement component 4. It can present with lupus-like symptoms. Parija (2009). Textbook of Microbiology...
    2 KB (81 words) - 04:09, 31 December 2019
  • Thumbnail for Complement component 3
    Deficiencies and defects of C3 result in the affected person being immunocompromised and particularly vulnerable to bacterial infections. Complement component...
    15 KB (1,758 words) - 15:36, 20 June 2025
  • can have chromosomal deficiencies, mental deficiencies, nutritional deficiencies, complement deficiencies, or enzyme deficiencies. Protein-energy malnutrition...
    4 KB (368 words) - 16:55, 21 May 2025
  • Thumbnail for Angioedema
    bradykinin formation is caused by continuous activation of the complement system due to a deficiency in one of its prime inhibitors, C1-esterase (aka: C1-inhibitor...
    26 KB (2,988 words) - 18:05, 24 February 2025
  • Thumbnail for MBL deficiency
    MBL deficiency or mannose-binding lectin deficiency is an illness that has an impact on immunity. Low levels of mannose-binding lectin, an immune system...
    10 KB (890 words) - 05:28, 29 January 2024
  • Thumbnail for Complement component 2
    the complement system, acting as a multi-domain serine protease. Deficiency of C2 has been associated with certain autoimmune diseases. The Complement system...
    16 KB (2,068 words) - 18:45, 14 January 2024
  • Thumbnail for Complement component 5
    the complement membrane attack complex. Deficiency is thought to cause Leiner's disease. Complement component 5 is the fifth component of complement, which...
    9 KB (1,114 words) - 14:39, 28 May 2025
  • Thumbnail for Hereditary angioedema
    hereditary angioedema (HAE). HAE types I and II are both caused by a deficiency of complement C1-inhibitor (C1-INH), a plasma protein that is an important inhibitor...
    41 KB (4,329 words) - 21:04, 29 May 2025
  • Thumbnail for Properdin deficiency
    Properdin deficiency is a rare X-linked disease in which properdin, an important complement factor responsible for the stabilization of the alternative...
    12 KB (1,434 words) - 00:55, 18 August 2024
  • CARD11 deficiency MST1 deficiency TCRα deficiency LCK deficiency IL-21 deficiency IL-21R deficiency UNC119 deficiency NIK deficiency OX40 deficiency IKBKB...
    19 KB (1,849 words) - 22:46, 1 June 2025
  • Thumbnail for Lupus
    and C4 by immune complex-induced inflammation or to congenitally complement deficiency, which may predispose to SLE. Renal disorder: More than 0.5 g per...
    139 KB (15,065 words) - 16:50, 20 June 2025
  • Thumbnail for Acquired C1 esterase inhibitor deficiency
    of the complement cascade, such that complement proteins remain in check and do not lead to unnecessary activity. When there is a deficiency of C1-INH...
    22 KB (2,252 words) - 09:45, 24 May 2025
  • Thumbnail for Classical complement pathway
    cells, killing them. Lack of regulation of the classical complement pathway through the deficiency in C1-inhibitor results in episodic angioedema. C1-inhibitor...
    16 KB (1,885 words) - 20:22, 29 May 2025
  • Thumbnail for Neisseria meningitidis
    response, such as a recent upper respiratory infection, smoking, and complement deficiency. The incubation period is short, from 2 to 10 days. In susceptible...
    41 KB (4,632 words) - 21:38, 29 May 2025
  • Thumbnail for Meningococcal disease
    "Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency"....
    51 KB (5,601 words) - 16:00, 7 June 2025
  • Thumbnail for Immunosuppression
    immunosuppression can occur in, for example, ataxia–telangiectasia, complement deficiencies, many types of cancer, and certain chronic infections such as human...
    10 KB (938 words) - 16:41, 3 December 2023
  • C3/C4 values but a decreased CH50, that can indicate a terminal complement pathway deficiency while if one has low C3 and CH50 values that can indicate an...
    5 KB (559 words) - 05:55, 27 May 2025
  • Coffin–Siris syndrome Cogan syndrome Cohen syndrome Compartment syndrome Complement deficiency Complete androgen insensitivity syndrome Complex regional pain syndrome...
    42 KB (4,068 words) - 11:23, 17 June 2025
  • Thumbnail for Complement component 1q
    the C1 complex (C1qr2s2), the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis...
    7 KB (691 words) - 18:41, 21 December 2023
  • Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system...
    35 KB (4,189 words) - 16:19, 7 November 2023
  • Thumbnail for Homocystinuria
    inherited disorder of the metabolism of the amino acid methionine due to a deficiency of cystathionine beta synthase or methionine synthase. It is an inherited...
    13 KB (1,363 words) - 21:19, 25 December 2024
  • Thumbnail for Lupus erythematosus
    but this is rare. When a single gene deficiency does cause lupus, it is usually attributed to the complement protein genes C1, C2, or C4. The influence...
    21 KB (2,129 words) - 16:02, 26 May 2025
  • Thumbnail for Meningitis
    such anatomical abnormalities, 36% are due to immune deficiencies (such as complement deficiency, which predisposes especially to recurrent meningococcal...
    90 KB (9,859 words) - 20:21, 13 June 2025
  • Schwartz RA, Thomas I. "Complement Receptor Deficiency: eMedicine Dermatology". Medscape. Retrieved 7 December 2010. Complement+receptors at the U.S. National...
    6 KB (376 words) - 06:42, 5 March 2024