Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins. Because of redundancies in...
15 KB (1,248 words) - 18:12, 28 January 2025
Complement 3 deficiency is a genetic condition affecting complement component 3 (C3). People can suffer from either primary or secondary C3 deficiency...
8 KB (828 words) - 23:36, 24 September 2024
Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC). It involves deficiencies of C5, C6...
3 KB (247 words) - 23:27, 7 March 2025
The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies...
43 KB (5,123 words) - 06:04, 18 June 2025
Complement 2 deficiency is a type of complement deficiency caused by any one of several different alterations in the structure of complement component...
11 KB (929 words) - 22:53, 19 June 2025
Immunodeficiency (redirect from Immune deficiency)
Asplenia, where there is no function of the spleen Complement deficiency is where the function of the complement system is deficient In reality, immunodeficiency...
28 KB (2,595 words) - 07:24, 9 June 2025
Complement 4 deficiency is a genetic condition affecting complement component 4. It can present with lupus-like symptoms. Parija (2009). Textbook of Microbiology...
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Deficiencies and defects of C3 result in the affected person being immunocompromised and particularly vulnerable to bacterial infections. Complement component...
15 KB (1,758 words) - 15:36, 20 June 2025
can have chromosomal deficiencies, mental deficiencies, nutritional deficiencies, complement deficiencies, or enzyme deficiencies. Protein-energy malnutrition...
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Angioedema (redirect from C1-esterase deficiency)
bradykinin formation is caused by continuous activation of the complement system due to a deficiency in one of its prime inhibitors, C1-esterase (aka: C1-inhibitor...
26 KB (2,988 words) - 18:05, 24 February 2025
MBL deficiency or mannose-binding lectin deficiency is an illness that has an impact on immunity. Low levels of mannose-binding lectin, an immune system...
10 KB (890 words) - 05:28, 29 January 2024
the complement system, acting as a multi-domain serine protease. Deficiency of C2 has been associated with certain autoimmune diseases. The Complement system...
16 KB (2,068 words) - 18:45, 14 January 2024
the complement membrane attack complex. Deficiency is thought to cause Leiner's disease. Complement component 5 is the fifth component of complement, which...
9 KB (1,114 words) - 14:39, 28 May 2025
Hereditary angioedema (redirect from C1-esterase inhibitor deficiency)
hereditary angioedema (HAE). HAE types I and II are both caused by a deficiency of complement C1-inhibitor (C1-INH), a plasma protein that is an important inhibitor...
41 KB (4,329 words) - 21:04, 29 May 2025
Properdin deficiency is a rare X-linked disease in which properdin, an important complement factor responsible for the stabilization of the alternative...
12 KB (1,434 words) - 00:55, 18 August 2024
CARD11 deficiency MST1 deficiency TCRα deficiency LCK deficiency IL-21 deficiency IL-21R deficiency UNC119 deficiency NIK deficiency OX40 deficiency IKBKB...
19 KB (1,849 words) - 22:46, 1 June 2025
Lupus (section Vitamin D deficiency)
and C4 by immune complex-induced inflammation or to congenitally complement deficiency, which may predispose to SLE. Renal disorder: More than 0.5 g per...
139 KB (15,065 words) - 16:50, 20 June 2025
of the complement cascade, such that complement proteins remain in check and do not lead to unnecessary activity. When there is a deficiency of C1-INH...
22 KB (2,252 words) - 09:45, 24 May 2025
cells, killing them. Lack of regulation of the classical complement pathway through the deficiency in C1-inhibitor results in episodic angioedema. C1-inhibitor...
16 KB (1,885 words) - 20:22, 29 May 2025
Neisseria meningitidis (section Complement inhibition)
response, such as a recent upper respiratory infection, smoking, and complement deficiency. The incubation period is short, from 2 to 10 days. In susceptible...
41 KB (4,632 words) - 21:38, 29 May 2025
"Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency"....
51 KB (5,601 words) - 16:00, 7 June 2025
immunosuppression can occur in, for example, ataxia–telangiectasia, complement deficiencies, many types of cancer, and certain chronic infections such as human...
10 KB (938 words) - 16:41, 3 December 2023
C3/C4 values but a decreased CH50, that can indicate a terminal complement pathway deficiency while if one has low C3 and CH50 values that can indicate an...
5 KB (559 words) - 05:55, 27 May 2025
Coffin–Siris syndrome Cogan syndrome Cohen syndrome Compartment syndrome Complement deficiency Complete androgen insensitivity syndrome Complex regional pain syndrome...
42 KB (4,068 words) - 11:23, 17 June 2025
the C1 complex (C1qr2s2), the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis...
7 KB (691 words) - 18:41, 21 December 2023
Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system...
35 KB (4,189 words) - 16:19, 7 November 2023
Homocystinuria (redirect from Methylcobalamin deficiency, cbl E complementation type)
inherited disorder of the metabolism of the amino acid methionine due to a deficiency of cystathionine beta synthase or methionine synthase. It is an inherited...
13 KB (1,363 words) - 21:19, 25 December 2024
but this is rare. When a single gene deficiency does cause lupus, it is usually attributed to the complement protein genes C1, C2, or C4. The influence...
21 KB (2,129 words) - 16:02, 26 May 2025
such anatomical abnormalities, 36% are due to immune deficiencies (such as complement deficiency, which predisposes especially to recurrent meningococcal...
90 KB (9,859 words) - 20:21, 13 June 2025
Schwartz RA, Thomas I. "Complement Receptor Deficiency: eMedicine Dermatology". Medscape. Retrieved 7 December 2010. Complement+receptors at the U.S. National...
6 KB (376 words) - 06:42, 5 March 2024