biochemistry, the conformation–activity relationship is the relationship between the biological activity and the chemical structure or conformational changes of...

Combinatorial chemistry Congener Conformation activity relationship Quantitative structure–activity relationship Pharmacophore Brown, Alexander Crum;...

Quantitative structure–activity relationship models (QSAR models) are regression or classification models used in the chemical and biological sciences...

Conformation activity relationship between the biological activity and the conformation or conformational changes of a biomolecule Equine conformation evaluates...

measure the conformational change in proteins, or other biomolecules, as they function (referred to as the conformation activity relationship). DPI focuses...

Suxamethonium Hexamethonium Lee C, Jones T (May 2002). "Molecular conformation-activity relationship of decamethonium congeners". British Journal of Anaesthesia...

 220–223. ISBN 0071624422. Lee C, Jones T (May 2002). "Molecular conformation-activity relationship of decamethonium congeners". British Journal of Anaesthesia...

Hibert MF, Hoffmann R, Miller RC, Carr AA (June 1990). "Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a...

Equine conformation evaluates a horse's bone structure, musculature, and its body proportions in relation to each other. Undesirable conformation can limit...

The Special Relationship is a term that is often used to describe the political, social, diplomatic, cultural, economic, legal, environmental, religious...

structures that experience conformational changes after being affected by interactions with other proteins or as a part of enzymatic activity. However, proteins...

proteins. It is now a common tool for the determination of Conformation Activity Relationships where the structure before and after interaction with, for...

the receptor-agonist relationship, but binding induces a conformational change and activates the receptor. This conformational change is often the result...

disease-related changes in tiny droplets within our cells". phys.org. "Conformation Activity Relationships - Why Do Molecules Change Shape?". 14 February 2010. Mashaghi...

coordination complexes. Cis and trans descriptors are not used for cases of conformational isomerism where the two geometric forms easily interconvert, such as...

ligand to the receptor causes a conformation change in the receptor. This conformation change can affect the activity of the receptor and result in the...

"partial" ergoline and conformationally constrained or rigid tryptamine which was developed during structure–activity relationship (SAR) studies of these...

that are the same stereoisomer as each other might be in different conformational forms or be different isotopologues. The depth of analysis depends on...

if a molecule exists in a particular conformation for a short lifetime, before adopting a lower energy conformation (structural arrangement), the former...

target protein. The binding typically results in a change of conformational isomerism (conformation) of the target protein. In DNA-ligand binding studies, the...

sugar (in the D or -1 subsite) in the hexasaccharide into a half-chair conformation. In this stressed state, the glycosidic bond is more easily broken. An...

mirror image by any combination of rotations, translations, and some conformational changes. This geometric property is called chirality (/kaɪˈrælɪti/)...

structures: no amount of re-orientation of a molecule as a whole or conformational change converts one chemical into its enantiomer. Chemical structures...

revealed an additional advantage of the conformational mechanism in allowing the subtle modulation of inhibitory activity, as notably seen at tissue level with...

The gene-for-gene relationship is a concept in plant pathology that plants and their diseases each have single genes that interact with each other during...

adjacent to the hinge region with a U-shaped conformation; but AM7 binds to c-Met in an extended conformation which spans the area from the hinge region...

phosphatidylinositol signal pathway. When a ligand binds to the GPCR it causes a conformational change in the GPCR, which allows it to act as a guanine nucleotide exchange...

where the binding of a small molecule causes a conformational change that increases or decreases activity. A small number of RNA-based biological catalysts...

1021/jm00378a021. PMID 6094812. Martin, J; Andrews, P (1987). "Conformation-activity relationships of opiate analgesics". J Comput Aided Mol Des. 1 (1): 53–72...

while preserving enzyme activity, thereby suggesting that all the information required by protein to adopt its final conformation is encoded in its amino-acid...