biochemistry, the conformation–activity relationship is the relationship between the biological activity and the chemical structure or conformational changes of...

Combinatorial chemistry Congener Conformation activity relationship Quantitative structure–activity relationship Pharmacophore Brown, Alexander Crum;...

Conformation activity relationship between the biological activity and the conformation or conformational changes of a biomolecule Equine conformation evaluates...

Quantitative structure–activity relationship (QSAR) models are regression or classification models used in the chemical and biological sciences and engineering...

measure the conformational change in proteins, or other biomolecules, as they function (referred to as the conformation activity relationship). DPI focuses...

Hibert MF, Hoffmann R, Miller RC, Carr AA (June 1990). "Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a...

 220–223. ISBN 0071624422. Lee C, Jones T (May 2002). "Molecular conformation-activity relationship of decamethonium congeners". British Journal of Anaesthesia...

The Special Relationship is a term that is often used to describe the political, social, diplomatic, cultural, economic, legal, environmental, religious...

Equine conformation evaluates a horse's bone structure, musculature, and its body proportions in relation to each other. Undesirable conformation can limit...

Suxamethonium Hexamethonium Lee C, Jones T (May 2002). "Molecular conformation-activity relationship of decamethonium congeners". British Journal of Anaesthesia...

structures that experience conformational changes after being affected by interactions with other proteins or as a part of enzymatic activity. However, proteins...

proteins. It is now a common tool for the determination of Conformation Activity Relationships where the structure before and after interaction with, for...

the receptor-agonist relationship, but binding induces a conformational change and activates the receptor. This conformational change is often the result...

1995). Structure-activity relationships of hallucinogens: Design, synthesis, and pharmacological evaluation of a series of conformationally restricted phenethylamines...

target protein. The binding typically results in a change of conformational isomerism (conformation) of the target protein. In DNA-ligand binding studies, the...

1021/jm00378a021. PMID 6094812. Martin, J; Andrews, P (1987). "Conformation-activity relationships of opiate analgesics". J Comput Aided Mol Des. 1 (1): 53–72...

sugar (in the D or -1 subsite) in the hexasaccharide into a half-chair conformation. In this stressed state, the glycosidic bond is more easily broken. An...

revealed an additional advantage of the conformational mechanism in allowing the subtle modulation of inhibitory activity, as notably seen at tissue level with...

coordination complexes. Cis and trans descriptors are not used for cases of conformational isomerism where the two geometric forms easily interconvert, such as...

ligand to the receptor causes a conformation change in the receptor. This conformation change can affect the activity of the receptor and result in the...

if a molecule exists in a particular conformation for a short lifetime, before adopting a lower energy conformation (structural arrangement), the former...

adjacent to the hinge region with a U-shaped conformation; but AM7 binds to c-Met in an extended conformation which spans the area from the hinge region...

mirror image by any combination of rotations, translations, and some conformational changes. This geometric property is called chirality (/kaɪˈrælɪti/)...

The gene-for-gene relationship is a concept in plant pathology that plants and their diseases each have single genes that interact with each other during...

enzyme's conformation by rearranging the nucleotide base sensing loop as compared to the dCK's conformation when bound to ATP. This change in conformation when...

agonist is bound. Firstly a conformation change to a higher affinity (but still shut) form, followed by the conformation change from shut to open. It...

disease-related changes in tiny droplets within our cells". phys.org. "Conformation Activity Relationships - Why Do Molecules Change Shape?". 14 February 2010. Mashaghi...

H. H.; Newman, A. H.; Katz, J. L.; Gether, U. (2007). "Relationship between Conformational Changes in the Dopamine Transporter and Cocaine-Like Subjective...

1995). Structure-activity relationships of hallucinogens: Design, synthesis, and pharmacological evaluation of a series of conformationally restricted phenethylamines...

catalytic activity. Studies have shown that conformational change of this loop region from the open conformation to the closed conformation after binding...