mRNA decapping complex is a protein complex in eukaryotic cells responsible for removal of the 5' cap. The active enzyme of the decapping complex is the...
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message from decapping. When translationally repressed or marked for decay by various mechanisms the 5' cap is bound by the mRNA decapping enzyme DCP2...
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contains the catalytic amino acids. NUDIX hydrolases include Dcp2 of the decapping complex, ADP-ribose diphosphatase, MutT, ADPRase, Ap4A hydrolases, RppH, and...
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destabilize the cap binding complex. The message is then subject to degradation by either the exosome complex or the decapping complex. In this way, translationally...
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processes take significant time. Decapping of a 7-methylguanylate-capped mRNA is catalyzed by the decapping complex made up of at least Dcp1 and Dcp2...
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mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene. DCP2 is a key component of an mRNA-decapping complex required for removal...
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protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated...
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M7GpppN-mRNA hydrolase (redirect from D10 decapping enzyme)
hydrolase (EC 3.6.1.62, DCP2, NUDT16, D10 protein, D9 protein, D10 decapping enzyme, decapping enzyme) is an enzyme with systematic name m7GpppN-mRNA m7GDP...
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inhibit poly(A) tail removal. Once the poly(A) tail is removed, the decapping complex removes the 5′ cap, leading to a degradation of the RNA. Several other...
57 KB (7,094 words) - 23:56, 6 August 2024
mRNA-decapping enzyme 1B is a protein that in humans is encoded by the DCP1B gene. DCP1B is a core component of the mRNA decapping complex, a key factor...
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EDC3 (redirect from Enhancer of mRNA-decapping protein 3)
Enhancer of mRNA-decapping protein 3 is a protein that in humans is encoded by the EDC3 gene. EDC3 is associated with an mRNA-decapping complex required for...
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sapiens (human) ]". Lykke-Andersen J (2002). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Mol. Cell...
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LE (2003). "Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities". Molecular Cell. 12 (3):...
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Izaurralde E (2005). "A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing". RNA. 11 (11): 1640–1647. doi:10...
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PMID 15231747. Lykke-Andersen J (Dec 2002). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Molecular...
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enriches proteins associated with 5’ mRNA decapping. It is thought to interact directly with Enhancer of mRNA Decapping 4 (EDC4). ELABELA (ELA) (a.k.a. APELA)...
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PMID 14527413. Lykke-Andersen, Jens (Dec 2002). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Mol. Cell...
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normal turnover of mRNA: 5′ to 3′ exonuclease (Xrn1), which is a dependent decapping protein; 3′ to 5′ exonuclease, an independent protein; and poly(A)-specific...
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miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes". Genes & Development. 20 (14): 1885–1898. doi:10.1101/gad.1424106...
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proposed to be the sites of mRNA degradation in the cell and involved in decapping and digestion of mRNAs earmarked for destruction. Later work called this...
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S2CID 389385. Lykke-Andersen J (2003). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Mol. Cell...
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mRNA Decapping”(1999) This paper examined promoters for decapping and how the promoters impede the translation and destruction of mRNA. “Decapping and...
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B-staging Potting (electronics) Quilt packaging Electronic packaging Decapping Rabaey, Jan (2007). Digital Integrated Circuits (2nd ed.). Prentice Hall...
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poxviruses have their enzymes for example vaccinia virus has decapping enzymes D9 and D10. Decapping enzymes that belong to the Nudix hydrolase superfamily...
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targets the RNA transcript for decay, facilitated by the non-canonical decapping enzyme, DXO. Considering the centrality of NAD in redox chemistry and...
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production by destabilizing its mRNA. Mice deficient in TTP develop a complex syndrome of inflammatory diseases. ZFP36 has been shown to interact with...
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allows for researchers to easily measure the kinetic activity of NAD-RNA decapping enzymes. Affinity capillary electrophoresis (ACE) refers to a number of...
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Gene expression (section Enhancers, transcription factors, mediator complex and DNA loops in mammalian transcription)
bound by cap binding complex heterodimer (CBP20/CBP80), which aids in mRNA export to cytoplasm and also protect the RNA from decapping. Another modification...
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substrates, leaving decapped and degrading mRNAs to be bound. 5′-monophosphorylated ends sequencing (5Pseq) captures both capped and decapped sequences to allow...
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Semiconductor, which is a joint venture co-owned by VIA. Unreleased CHA Processor Decapped CHA Processor Die shot of the CHA Processor Note: Even the 180 nm Duron...
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