EMPA is a selective antagonist of the OX2 receptor, with 900-fold selectivity in binding for OX2 over OX1. TCS-OX2-29 Malherbe P, Borroni E, Pinard E,...
3 KB (131 words) - 02:27, 8 May 2023
Administration Consortium EMPA (drug) Electron micro probe analyzer (EMPA) Euro-Mediterranean Parliamentary Assembly Empa, Cyprus, a community of Cyprus...
443 bytes (73 words) - 17:45, 28 March 2022
Empagliflozin (category Drugs with non-standard legal status)
co-transporter-2 inhibition in people with chronic kidney disease: a rationale for the EMPA-KIDNEY study". Clinical Kidney Journal. 13 (4): 722. doi:10.1056/NEJMoa2204233...
39 KB (3,481 words) - 21:56, 19 May 2024
(ACT-078573) – dual OX1 and OX2 antagonist – development of the drug was abandoned in January 2011 EMPA – selective OX2 antagonist Filorexant (MK-6096) – dual...
19 KB (1,978 words) - 11:32, 1 May 2024
Dapagliflozin (category Multiple chemicals in Infobox drug)
Retrieved 14 January 2024. "Dapagliflozin - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024. The EMPA-KIDNEY Collaborative Group (12 January 2023)...
53 KB (4,939 words) - 05:15, 20 May 2024
and OX2 receptor antagonist ACT-335827 – selective OX1 receptor antagonist EMPA – selective OX2 receptor antagonist JNJ-10397049 – selective OX2 receptor...
11 KB (1,052 words) - 15:41, 14 January 2024
Daridorexant (category Infobox drug with local INN variant)
and a time to peak of about 1 to 2 hours. It is not a benzodiazepine or Z-drug and does not interact with GABA receptors, instead having a distinct mechanism...
48 KB (4,075 words) - 03:39, 13 May 2024
in 2011 to the International Motor Sports Hall of Fame in Talladega, AL. "EMPA Hall of Fame-Jan Opperman". Eastern Motorsport Press Association. Retrieved...
4 KB (472 words) - 17:16, 30 December 2023
Danavorexton (category Nervous system drug stubs)
October 2021. Orexin receptor § Agonists List of investigational sleep drugs § Orexin receptor agonists Jacobson LH, Hoyer D, de Lecea L (January 2022)...
5 KB (301 words) - 11:39, 13 January 2024
Suvorexant (category Drugs developed by Merck & Co.)
other orexin antagonists, but is lower than that of benzodiazepines and Z-drugs. Suvorexant is taken by mouth. Side effects of suvorexant include somnolence...
94 KB (8,958 words) - 03:36, 8 February 2024
and a time to peak of about 1 to 3 hours. It is not a benzodiazepine or Z-drug and does not interact with GABA receptors, instead having a distinct mechanism...
21 KB (1,687 words) - 04:21, 27 January 2024
JNJ-61393215 (category Nervous system drug stubs)
development has been reported for treatment of other anxiety disorders. The drug was originated and developed by Janssen Pharmaceuticals. List of investigational...
5 KB (267 words) - 22:16, 3 December 2023
with chronic kidney disease. More recently, his group has completed the EMPA-KIDNEY trial, which recruited over 6,600 patients, and demonstrated the efficacy...
11 KB (891 words) - 22:21, 5 July 2023
Seltorexant (category Drugs not assigned an ATC code)
receptor antagonists for the treatment of insomnia disorders". Expert Opin Drug Metab Toxicol. 16 (11): 1063–1078. doi:10.1080/17425255.2020.1817380. PMID 32901578...
7 KB (498 words) - 07:20, 7 January 2024
Vornorexant (category Nervous system drug stubs)
investigational short-acting orexin receptor antagonist List of investigational sleep drugs § Orexin receptor antagonists Uchiyama M, Kambe D, Imadera Y, Kajiyama Y...
6 KB (390 words) - 00:26, 3 January 2024
Filorexant (category Nervous system drug stubs)
listed on Merck's online development pipeline and hence development of the drug appears to have been discontinued. Development of filorexant may have been...
8 KB (670 words) - 14:33, 29 December 2023
Almorexant (category Drugs not assigned an ATC code)
companies Actelion and GSK for the treatment of insomnia. Development of the drug was abandoned in January 2011 due to concerns over the hepatic safety of...
8 KB (606 words) - 16:15, 31 March 2024
several hours of exposure. The serum level of ethyl methylphosphonic acid (EMPA), a VX hydrolysis product, was measured to confirm exposure in one poisoning...
49 KB (5,385 words) - 17:22, 11 May 2024
ACT-539313 (category Nervous system drug stubs)
a selective orexin OX1 receptor antagonist (1-SORA). As of May 2022, the drug is in phase 2 clinical trials for binge eating disorder. Following negative...
6 KB (402 words) - 20:39, 1 December 2023
ACT-335827 (category Nervous system drug stubs)
TAK-861 TAK-994 Antagonists: ACT-335827 ACT-462206 Almorexant Daridorexant EMPA Filorexant GSK-649868 (SB-649868) JNJ-10397049 Lemborexant MK-1064 MK-3697...
3 KB (122 words) - 23:08, 1 April 2023
Firazorexton (category Chemical pages without DrugBank identifier)
investigational sleep drugs § Orexin receptor agonists "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). WHO Drug Information. 34...
8 KB (532 words) - 07:00, 2 November 2023
Suntinorexton (category Nervous system drug stubs)
investigational sleep drugs § Orexin receptor agonists "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). WHO Drug Information. 34...
3 KB (117 words) - 23:03, 30 January 2024
Ventura J, ed. (2014-08-31). "FDA approves new type of sleep drug, Belsomra". Food and Drug Administration (FDA). Retrieved 2015-10-31. "Dayvigo- lemborexant...
54 KB (6,129 words) - 07:14, 8 May 2024
offshoots, such as the manufacturer of metal-organic frameworks novoMOF or the drug developer leadXpro, have settled close to PSI in the Park Innovaare, which...
48 KB (5,849 words) - 01:20, 18 May 2024
SB-334867 (category Chemical pages without DrugBank identifier)
have multiple potential clinical applications including the treatment of drug addiction, insomnia, obesity and diabetes. Smart D, Sabido-David C, Brough...
10 KB (996 words) - 21:32, 22 January 2024
and Strategy. The school offers six graduate degrees: the MAcc, MBA, EMBA, EMPA, MISM, and MPA. MBA students choose a major (Finance, Marketing, Supply Chain...
64 KB (5,784 words) - 00:23, 30 March 2024
ACT-462206 (category Nervous system drug stubs)
TAK-861 TAK-994 Antagonists: ACT-335827 ACT-462206 Almorexant Daridorexant EMPA Filorexant GSK-649868 (SB-649868) JNJ-10397049 Lemborexant MK-1064 MK-3697...
3 KB (176 words) - 23:08, 1 April 2023
RTIOX-276 (category Chemical pages without DrugBank identifier)
TAK-861 TAK-994 Antagonists: ACT-335827 ACT-462206 Almorexant Daridorexant EMPA Filorexant GSK-649868 (SB-649868) JNJ-10397049 Lemborexant MK-1064 MK-3697...
3 KB (202 words) - 16:41, 7 November 2022
(Dr. August Wolff; Hungary) [solution applied to the scalp] Cridermol Fem (EMPA; Paraguay) [vaginal cream] Ginabiot (Tecnofarma; Paraguay) [vaginal cream]...
7 KB (596 words) - 21:01, 11 November 2023
and OX2 antagonist Daridorexant (nemorexant) - Dual OX1 and OX2 antagonist EMPA - Selective OX2 antagonist Filorexant - Dual OX1 and OX2 antagonist JNJ-10397049...
17 KB (1,639 words) - 17:01, 2 April 2024