The endocannabinoid transporters (eCBTs) are transport proteins for the endocannabinoids. Most neurotransmitters are water-soluble and require transmembrane...

The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and...

are multi-ring phenolic compounds structurally related to THC, but endocannabinoids are fatty acid derivatives. Nonclassical synthetic cannabinoids (cannabimimetics)...

decades, and a putative endocannabinoid membrane transporter was proposed. However, as lipophilic molecules endocannabinoids readily pass through the...

monoacylglycerol lipase (MAGL) inhibitors, and endocannabinoid transporter (eCBT) inhibitors (or "endocannabinoid reuptake inhibitors" ("eCBRIs")). An example...

Oleoylethanolamide Olvanil PSN-375,963 PSN-632,408 Transporter (modulators) eCBTsTooltip Endocannabinoid transporter Inhibitors: 5'-DMH-CBD AM-404 AM-1172 Arachidonoyl...

Oleoylethanolamide Olvanil PSN-375,963 PSN-632,408 Transporter (modulators) eCBTsTooltip Endocannabinoid transporter Inhibitors: 5'-DMH-CBD AM-404 AM-1172 Arachidonoyl...

Oleoylethanolamide Olvanil PSN-375,963 PSN-632,408 Transporter (modulators) eCBTsTooltip Endocannabinoid transporter Inhibitors: 5'-DMH-CBD AM-404 AM-1172 Arachidonoyl...

Ligresti A, Villano R, Allarà M, et al. (2012). "Kavalactones and the endocannabinoid system: the plant-derived yangonin is a novel CB₁ receptor ligand"...

agonist of GPR55 and l-α-lysophosphatidylinositol (LPI), and beyond the endocannabinoid system, THCV also activate 5-HT1A receptors to produce an antipsychotic...

Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system of vertebrates– a class of cell membrane receptors in the G...

of reuptake modulators. It is a drug that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic...

inhibitor of endocannabinoid transporter, and a potent activator of TRPV1 receptor. This and other research indicate that the endocannabinoid system and...

It may therefore increase anandamide's physiological effects. Endocannabinoid transporters for anandamide and 2-arachidonoylglycerol include the heat shock...

Oleoylethanolamide Olvanil PSN-375,963 PSN-632,408 Transporter (modulators) eCBTsTooltip Endocannabinoid transporter Inhibitors: 5'-DMH-CBD AM-404 AM-1172 Arachidonoyl...

eCBTsTooltip Endocannabinoid transporter Inhibitors: 5'-DMH-CBD AM-404 AM-1172 Arachidonoyl serotonin Arvanil Cannabidiol Guineensine LY-2183240 O-2093...

Anandamide (N-arachidonoylethanolamine), an endocannabinoid 2-arachidonoylglycerol (2-AG), an endocannabinoid. Other N-acylethanolamines, such as N-oleoylethanolamine...

eCBTsTooltip Endocannabinoid transporter Inhibitors: 5'-DMH-CBD AM-404 AM-1172 Arachidonoyl serotonin Arvanil Cannabidiol Guineensine LY-2183240 O-2093...

never marketed. It is currently used as a research tool to study the endocannabinoid system. CP 55,940 is 45 times more potent than Δ9-THC, and fully antagonized...

synthetic phytocannabinoids (obtained by chemical synthesis) or synthetic endocannabinoids from which they are distinct in many aspects. Typically, synthetic...

activity at CB1 and CB2 receptors constitutes interaction of CBN with the endocannabinoid system (ECS). Although CBN shares the same mechanism of action as other...

by the action of a phosphatase. 2-Arachidonoyl glyceryl ether Endocannabinoid transporters Stella N, Schweitzer P, Piomelli D (August 1997). "A second endogenous...

protective effects against schizophrenia. Pregnenolone is an allosteric endocannabinoid, as it is a negative allosteric modulator of the CB1 receptor. Pregnenolone...

"Nabilone label" (PDF). FDA. May 2006. Fine PG, Rosenfeld MJ (2013). "The endocannabinoid system, cannabinoids, and pain". Rambam Maimonides Medical Journal...

has been well characterised as involving endocannabinoid transporter inhibition, but the precise transporter responsible is yet to be determined. AM404...

arthritis. These compounds work by mimicking the body's naturally-produced endocannabinoid hormones such as 2-AG and anandamide (AEA), which are biologically...

in the analgesic effects of CBG. It shows no inhibition of several endocannabinoid-metabolizing enzymes including fatty acid amide hydrolase (FAAH), diacylglycerol...

receptor 1 (CB1), which is largely responsible for the efficacy of endocannabinoid-mediated presynaptic-inhibition, the psychoactive properties of tetrahydrocannabinol...

activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs. The discovery of the endocannabinoid system led to...

receptors GPR55 and GPR119. PEA cannot strictly be considered a classic endocannabinoid because it lacks affinity for the cannabinoid receptors CB1 and CB2...