An exon junction complex (EJC) is a protein complex which forms on a pre-messenger RNA strand at the junction of two exons which have been joined together...
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up-frameshift (UPF) proteins. In mammals, UPF2 and UPF3 are part of the exon-exon junction complex (EJC) bound to mRNA after splicing along with other proteins,...
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controlled by exon architecture and exon junction complexes. Exon junction complexes suppress m6A methylation near exon-exon junctions by packaging nearby...
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RNA splicing (redirect from Splice junction)
circular RNAs, the junction is a 2'-5'link. Wikimedia Commons has media related to Splicing. cDNA DBASS3/5 Exon junction complex mRNA capping Polyadenylation...
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nucleocytoplasmic shuttling protein. It complexes with RBM8A to bind specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm...
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Rappsilber J, et al. (Jan 2004). "eIF4A3 is a novel component of the exon junction complex". RNA. 10 (2): 200–9. doi:10.1261/rna.5230104. PMC 1370532. PMID 14730019...
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SR protein (section Exon dependent roles)
ESS for an hnRNP to bind and block splicing of the exon. Spliceosome Exon Intron Exon Junction Complex Long JC, Caceres JF (January 2009). "The SR protein...
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mago nashi protein, is a component of the splicing-dependent exon–exon junction complex". EMBO J. 20 (22). England: 6424–33. doi:10.1093/emboj/20.22.6424...
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of the EJC (exon junction complex) which is a complex that is involved in post-transcriptional regulation of mRNA in metazoa. The complex is formed by...
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from the last exon boundary whereas natural stop codons are located within terminal exons. Exon junction complexes (EJCs) mark the exon-exon boundaries....
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encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance...
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melanogaster, Mago Nashi and Tsunagi/Y14 are core components of the exon junction complex. They complex with novel zinc finger protein Ranshi, which is involved...
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shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of...
9 KB (1,176 words) - 23:46, 4 September 2022
encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance...
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core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated...
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Messenger RNP (category Protein complexes)
vertebrates exon-exon junction are marked by exon junction complexes which in the cytosol can trigger nonsense mediated decay if the exon-exon junction is more...
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nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex". Science. 293 (5536): 1832–6. Bibcode:2001Sci...293.1832K. doi:10...
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localization of Arc to neuronal dendrites, as well as sites for two exon junction complexes (EJCs) that make Arc a natural target for nonsense mediated decay...
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PMID 11991638. Lejeune F, Ishigaki Y, Li X, Maquat LE (2002). "The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian...
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Gene expression (section Enhancers, transcription factors, mediator complex and DNA loops in mammalian transcription)
type. mRNA transport also requires the correct association with Exon Junction Complex (EJC), which ensures that correct processing of the mRNA is completed...
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protein complex-bound mRNA has a stop codon that is found more than 50-55 nucleotides upstream of an exon-junction complex-bearing exon-exon junction. The...
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letters, 742, 135514. Leung, C. S., & Johnson, T. L. (2018). The Exon Junction Complex: A Multitasking Guardian of the Transcriptome. Molecular cell, 72(5)...
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as the TREX complex in facilitating the mRNA export from the nucleus to the cytoplasm. NCBP3 further interact with exon junction complex proteins for...
27 KB (3,090 words) - 19:20, 26 May 2025
encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance...
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Split gene theory (section Short exons/long introns)
split gene architecture, including split eukaryotic genes, exons, introns, splice junctions, and branch points, based on the origin of split genes from...
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MTORC1 (redirect from Mechanistic target of rapamycin complex 1)
pre-initiation complex. Active S6K can bind to the SKAR scaffold protein that can get recruited to exon junction complexes (EJC). Exon junction complexes span the...
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to the other isoforms is believed to be a core component of the exon junction complex involved in pre-mRNA splicing. Eukaryotic initiation factor Eukaryotic...
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upstream exon. Alternative acceptor site: An alternative 3' splice junction (acceptor site) is used, changing the 5' boundary of the downstream exon. Intron...
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that the mRNA contains exons and introns in the strand. This is because the machinery for NMD recognizes exon-junctions complexes. Unlike translational...
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Prinos P, Chabot B (March 2012). "Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators"....
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