protein 46. Exosome component 1 has been shown to interact with: Exosome component 5, Exosome component 6, and Exosome component 7. GRCh38: Ensembl release...

Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...

Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...

component 6 has been shown to interact with Exosome component 7,Exosome component 8 and Exosome component 1. GRCh38: Ensembl release 89: ENSG00000223496 –...

component 7 has been shown to interact with: Exosome component 1, Exosome component 2, and Exosome component 6. GRCh38: Ensembl release 89: ENSG00000075914...

Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...

Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...

Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...

Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...

Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...

The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...

transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1 hypermethylation the 5'-methylguanosine...

The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...

thrombosis in patients with these conditions. PAI-1 can induce cellular senescence. PAI-1 can also be a component of the senescence-associated secretory phenotype...

Enolase 1 (ENO1), more commonly known as alpha-enolase, is a glycolytic enzyme expressed in most tissues, one of the isozymes of enolase. Each isoenzyme...

Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms...

large, extracellular matrix glycoprotein that serves as a structural component of 10–12 nm calcium-binding microfibrils. These microfibrils provide force...

to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport...

Phosphoglucomutase-1 is an enzyme that in humans is encoded by the PGM1 gene. The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM)...

transmembrane receptors, and extracellular components. The intercellular interaction between MUC-1 and the receptor ICAM-1 facilitates endothelial and epithelial...

to be an artifact stemming from DJ-1's ability to destroy free methylglyoxal. The gene PARK7, also known as DJ-1, encodes a protein of the peptidase...

system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein is critical...

length for stable binding onto MHC class I molecules (Figure 1). ERAP1, like other APP components, is induced by interferon gamma, a cytokine inducing antigen...

Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...

Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...

Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member...

is encoded by the GJA1 gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular communication...

glutathione reductase has been implicated in the oxidative burst, a component of the immune response. The oxidative burst is a defense mechanism in...

Beta-defensin 1 is a protein that in humans is encoded by the DEFB1 gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils...

National Library of Medicine. "Entrez Gene: CR1 complement component (3b/4b) receptor 1 (Knops blood group)". Moulds JM, Nickells MW, Moulds JJ, Brown...