Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...
6 KB (614 words) - 17:16, 16 July 2025
component 6 has been shown to interact with Exosome component 7,Exosome component 8 and Exosome component 1. GRCh38: Ensembl release 89: ENSG00000223496 –...
4 KB (516 words) - 17:16, 16 July 2025
Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
9 KB (971 words) - 05:46, 19 July 2025
Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
6 KB (777 words) - 05:46, 19 July 2025
Exosome component 7, also known as EXOSC7, is a human gene, the protein product of which is part of the exosome complex. Exosome component 7 has been shown...
6 KB (717 words) - 04:09, 15 July 2025
Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
7 KB (858 words) - 17:16, 16 July 2025
encoded by the EXOSC1 gene. This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing...
7 KB (782 words) - 05:46, 19 July 2025
Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
8 KB (1,045 words) - 16:32, 17 July 2025
Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
8 KB (797 words) - 05:46, 19 July 2025
Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
6 KB (702 words) - 21:41, 15 July 2025
The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
43 KB (4,589 words) - 17:33, 6 November 2024
The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
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exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
23 KB (2,549 words) - 18:46, 16 July 2025
mitochondria, plastids and as a constituent of the archaeal exosome (in those archaea that have an exosome). It can synthesise a 3′ extension where the vast majority...
57 KB (7,094 words) - 23:56, 6 August 2024
to interact with CD44, CD49d, CD29 and CD49c. It also interacts with components of the mTORC1 complex. GRCh38: Ensembl release 89: ENSG00000116977 – Ensembl...
12 KB (1,448 words) - 05:53, 19 July 2025
to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport...
54 KB (6,074 words) - 21:14, 22 May 2025
for the detection of a chemical substance, that combines a biological component with a physicochemical detector. The sensitive biological element, e.g...
106 KB (12,175 words) - 23:05, 16 July 2025
MUC16 is thought to be cleaved at a site in the SEA modules. MUC16 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory...
16 KB (1,916 words) - 18:26, 3 December 2023
of the first component of complement. C1r and C1s associated with a lupus erythematosus-like disease". Arthritis and Rheumatism. 21 (8): 958–67. doi:10...
10 KB (1,273 words) - 20:03, 12 May 2024
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
10 KB (1,195 words) - 16:58, 16 July 2025
Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily...
5 KB (631 words) - 18:52, 16 July 2025
gait problems (problems with walking) seem to be early signs of CTEM. Exosome vesicles created by the brain are potential biomarkers of TBI, including...
69 KB (7,243 words) - 15:01, 16 July 2025
Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to...
7 KB (838 words) - 17:07, 16 July 2025
Glutathione reductase (redirect from EC 1.8.1.7)
glutathione reductase has been implicated in the oxidative burst, a component of the immune response. The oxidative burst is a defense mechanism in...
31 KB (3,697 words) - 12:39, 23 June 2025
200 nm. EVs can be divided according to size and synthesis route into exosomes, microvesicles and apoptotic bodies. The composition of EVs varies depending...
63 KB (6,981 words) - 07:45, 9 June 2025
DPYS (category Genes on human chromosome 8)
high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria...
4 KB (530 words) - 04:06, 15 July 2025
genes implicated in epidermal barrier function". Genome Biol. 8 (6) R107. doi:10.1186/gb-2007-8-6-r107. PMC 2394760. PMID 17562024. This article incorporates...
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binding cytochrome-c oxidase activity Cellular component mitochondrial inner membrane extracellular exosome membrane mitochondrion nucleus mitochondrial...
12 KB (1,397 words) - 16:12, 17 July 2025
Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
9 KB (1,114 words) - 04:01, 15 July 2025