Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...
6 KB (614 words) - 17:16, 16 July 2025
component 6 has been shown to interact with Exosome component 7,Exosome component 8 and Exosome component 1. GRCh38: Ensembl release 89: ENSG00000223496 –...
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Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
9 KB (971 words) - 05:46, 19 July 2025
Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
6 KB (777 words) - 05:46, 19 July 2025
Exosome component 7, also known as EXOSC7, is a human gene, the protein product of which is part of the exosome complex. Exosome component 7 has been shown...
6 KB (717 words) - 04:09, 15 July 2025
Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
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encoded by the EXOSC1 gene. This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing...
7 KB (782 words) - 05:46, 19 July 2025
Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
8 KB (797 words) - 05:46, 19 July 2025
Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
8 KB (1,045 words) - 16:32, 17 July 2025
Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
6 KB (702 words) - 21:41, 15 July 2025
The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
43 KB (4,589 words) - 17:33, 6 November 2024
The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
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exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
23 KB (2,549 words) - 18:46, 16 July 2025
Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene. This gene is a member of the integrin beta chain family and encodes a single-pass...
7 KB (825 words) - 06:09, 19 July 2025
mitochondria, plastids and as a constituent of the archaeal exosome (in those archaea that have an exosome). It can synthesise a 3′ extension where the vast majority...
57 KB (7,094 words) - 23:56, 6 August 2024
to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport...
54 KB (6,074 words) - 21:14, 22 May 2025
Glutathione reductase (redirect from EC 1.8.1.7)
glutathione reductase has been implicated in the oxidative burst, a component of the immune response. The oxidative burst is a defense mechanism in...
31 KB (3,701 words) - 12:52, 26 July 2025
MUC16 is thought to be cleaved at a site in the SEA modules. MUC16 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory...
16 KB (1,916 words) - 18:26, 3 December 2023
for the detection of a chemical substance, that combines a biological component with a physicochemical detector. The sensitive biological element, e.g...
106 KB (12,175 words) - 23:05, 16 July 2025
Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
9 KB (1,114 words) - 04:01, 15 July 2025
DPYS (category Genes on human chromosome 8)
high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria...
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of the first component of complement. C1r and C1s associated with a lupus erythematosus-like disease". Arthritis and Rheumatism. 21 (8): 958–67. doi:10...
10 KB (1,273 words) - 20:03, 12 May 2024
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
10 KB (1,195 words) - 16:58, 16 July 2025
gait problems (problems with walking) seem to be early signs of CTEM. Exosome vesicles created by the brain are potential biomarkers of TBI, including...
69 KB (7,243 words) - 15:01, 16 July 2025
prion form. In 2015 it was reported that the presence of this protein in exosomes in patients' blood is able to detect early pancreatic cancer with absolute...
16 KB (1,777 words) - 21:44, 15 July 2025
system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein is critical...
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to interact with CD44, CD49d, CD29 and CD49c. It also interacts with components of the mTORC1 complex. GRCh38: Ensembl release 89: ENSG00000116977 – Ensembl...
12 KB (1,448 words) - 05:53, 19 July 2025
Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily...
5 KB (631 words) - 18:52, 16 July 2025
Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to...
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genes implicated in epidermal barrier function". Genome Biol. 8 (6) R107. doi:10.1186/gb-2007-8-6-r107. PMC 2394760. PMID 17562024. This article incorporates...
4 KB (529 words) - 11:24, 16 July 2025