• Thumbnail for Exosome component 8
    Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...
    6 KB (614 words) - 17:16, 16 July 2025
  • Thumbnail for Exosome component 6
    component 6 has been shown to interact with Exosome component 7,Exosome component 8 and Exosome component 1. GRCh38: Ensembl release 89: ENSG00000223496 –...
    4 KB (516 words) - 17:16, 16 July 2025
  • Thumbnail for Exosome component 5
    Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
    9 KB (971 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome component 4
    Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
    6 KB (777 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome component 7
    Exosome component 7, also known as EXOSC7, is a human gene, the protein product of which is part of the exosome complex. Exosome component 7 has been shown...
    6 KB (717 words) - 04:09, 15 July 2025
  • Thumbnail for Exosome component 10
    Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
    7 KB (858 words) - 17:16, 16 July 2025
  • Thumbnail for Exosome component 1
    encoded by the EXOSC1 gene. This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing...
    7 KB (782 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome component 2
    Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
    8 KB (1,045 words) - 16:32, 17 July 2025
  • Thumbnail for Exosome component 9
    Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
    8 KB (797 words) - 05:46, 19 July 2025
  • Thumbnail for Exosome component 3
    Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
    6 KB (702 words) - 21:41, 15 July 2025
  • Thumbnail for Exosome complex
    The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
    43 KB (4,589 words) - 17:33, 6 November 2024
  • Thumbnail for Serum amyloid P component
    The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
    6 KB (744 words) - 18:35, 16 July 2025
  • Thumbnail for Telomerase RNA component
    exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
    23 KB (2,549 words) - 18:46, 16 July 2025
  • mitochondria, plastids and as a constituent of the archaeal exosome (in those archaea that have an exosome). It can synthesise a 3′ extension where the vast majority...
    57 KB (7,094 words) - 23:56, 6 August 2024
  • Thumbnail for Galectin-8
    to interact with CD44, CD49d, CD29 and CD49c. It also interacts with components of the mTORC1 complex. GRCh38: Ensembl release 89: ENSG00000116977 – Ensembl...
    12 KB (1,448 words) - 05:53, 19 July 2025
  • Thumbnail for Microvesicle
    to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport...
    54 KB (6,074 words) - 21:14, 22 May 2025
  • for the detection of a chemical substance, that combines a biological component with a physicochemical detector. The sensitive biological element, e.g...
    106 KB (12,175 words) - 23:05, 16 July 2025
  • Thumbnail for Mucin-16
    MUC16 is thought to be cleaved at a site in the SEA modules. MUC16 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory...
    16 KB (1,916 words) - 18:26, 3 December 2023
  • Thumbnail for Complement component 1r
    of the first component of complement. C1r and C1s associated with a lupus erythematosus-like disease". Arthritis and Rheumatism. 21 (8): 958–67. doi:10...
    10 KB (1,273 words) - 20:03, 12 May 2024
  • Thumbnail for Complement component 1s
    Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
    10 KB (1,195 words) - 16:58, 16 July 2025
  • Thumbnail for TSPAN8
    Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily...
    5 KB (631 words) - 18:52, 16 July 2025
  • Thumbnail for Chronic traumatic encephalopathy
    gait problems (problems with walking) seem to be early signs of CTEM. Exosome vesicles created by the brain are potential biomarkers of TBI, including...
    69 KB (7,243 words) - 15:01, 16 July 2025
  • Thumbnail for DIS3
    Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to...
    7 KB (838 words) - 17:07, 16 July 2025
  • Thumbnail for HLA-C
    HLA-C (redirect from HLA-Cw*8)
    goiters: study in a population from southeastern Spain". Arch Surg. 141 (2): 123–8. doi:10.1001/archsurg.141.2.123. PMID 16490887. Montes-Ares O, Moya-Quiles...
    8 KB (1,014 words) - 03:35, 28 December 2023
  • Thumbnail for Glutathione reductase
    glutathione reductase has been implicated in the oxidative burst, a component of the immune response. The oxidative burst is a defense mechanism in...
    31 KB (3,697 words) - 12:39, 23 June 2025
  • 200 nm. EVs can be divided according to size and synthesis route into exosomes, microvesicles and apoptotic bodies. The composition of EVs varies depending...
    63 KB (6,981 words) - 07:45, 9 June 2025
  • Thumbnail for DPYS
    DPYS (category Genes on human chromosome 8)
    high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria...
    4 KB (530 words) - 04:06, 15 July 2025
  • Thumbnail for A2ML1
    genes implicated in epidermal barrier function". Genome Biol. 8 (6) R107. doi:10.1186/gb-2007-8-6-r107. PMC 2394760. PMID 17562024. This article incorporates...
    4 KB (529 words) - 11:24, 16 July 2025
  • Thumbnail for COX4I1
    binding cytochrome-c oxidase activity Cellular component mitochondrial inner membrane extracellular exosome membrane mitochondrion nucleus mitochondrial...
    12 KB (1,397 words) - 16:12, 17 July 2025
  • Thumbnail for Complement component 5
    Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
    9 KB (1,114 words) - 04:01, 15 July 2025