Factor IX (EC 3.4.21.22), also known as Christmas factor, is one of the serine proteases involved in coagulation; it belongs to peptidase family S1. Deficiency...

inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A)....

known as factor IX complex, sold under the brand name Kcentra among others, is a combination medication made up of blood clotting factors II, IX, and X(3-factor...

Willebrand factor (vWF), which is released from the endothelium and from platelets; vWF forms additional links between the platelets' glycoprotein Ib/IX/V and...

Factor X is synthesized in the liver and requires vitamin K for its synthesis. Factor X is activated, by hydrolysis, into factor Xa by both factor IX...

coagulation factor VII), which in turn activates factor IX and factor X. Using genetic recombination a recombinant factor VIIa (eptacog alfa) (trade names include...

gene for clotting Factor IX. The gene is expressed in the liver to produce Factor IX protein, to increase blood levels of Factor IX and thereby limit...

prekallikrein, factor XII, factor XI, and factor IX). Factor XIa activates factor IX by selectively cleaving arg-ala and arg-val peptide bonds. Factor IXa, in...

sequence of the RNA for Factor IX by examining the amino acids in Factor IX: Microsequencing of highly purified... [Factor IX] yielded sufficient amino...

occurs due to low amounts of clotting factor VIII, and haemophilia B, which occurs due to low levels of clotting factor IX. They are typically inherited from...

Willebrand factor. The active protein (sometimes written as coagulation factor VIIIa) interacts with another coagulation factor called factor IX. This interaction...

in Factor II, Factor VII, Factor IX, and Factor X. Plasma from patients on oral anticoagulants (Warfarin etc.) for 48–72 hours is deficient in Factor VII...

human diseases. The protein in question was the human blood clotting factor IX. Another difference from Dolly the Sheep was the source cell type of the...

activated coagulation factor IX and to factor X, mediating the activation of the latter. This is normally the function of coagulation factor VIII, which is missing...

clotting disorder caused by a mutation of the Factor IX gene and leading to a deficiency of Factor IX. It is rarer than hemophilia A. As noted above...

factor from damaged tissue. Tissue factor binds to circulating factor VIIa. The combination activates factor X to factor Xa and factor IX to factor IXa...

adeno-associated virus used for the treatment of hemophilia B (congenital Factor IX deficiency). Fidanacogene elaparvovec was approved for medical use in...

factor VIII concentrate Berinin P, freeze-dried human coagulation factor IX concentrate Factor X P Behring, a freeze-dried human coagulation factor IX...

Intrinsic tenase complex contains the active factor IX (IXa), its cofactor factor VIII (VIIIa), the substrate (factor X), and they are activated by negatively...

hemophilia by cloning the canine Factor IX gene. She also identified the mutations responsible for several Factor VII and Factor X-deficient blood clotting...

Herzog RW (January 2014). "Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B". Journal...

Specifically, they found a single-nucleotide change in the gene for clotting Factor IX that causes incorrect RNA splicing and produces a truncated, nonfunctional...

levels of active clotting factor. Two of the most common differential diagnoses are haemophilia B which is a deficiency in Factor IX and von Willebrand Disease...

Financial Reporting, a financial reporting software application Factor IX, a coagulation factor F9, a function key on a computer keyboard Zeolite F-9, a sodium-type...

adeno-associated viral vector which is designed to transfer a working copy of the Factor IX gene into the livers of patients who carry non-functioning copies. It...

factor VIIa, which is an activated form of factor VII, bypasses factors VIII and IX and causes coagulation without the need for factors VIII and IX....

vitamin K is required to introduce γ-carboxylation of clotting factors II, VII, IX, X and protein Z. In the biosynthesis of γ-carboxyglutamic acid,...

deficiency of Factor VIII causes classic hemophilia A while deficiencies of Factor IX cause "Christmas disease"(hemophilia B). Antibodies to Factor VIII can...

age and older with hemophilia A or hemophilia B, with or without factor VIII or IX inhibitors (neutralizing antibodies). The US Food and Drug Administration...

to 2008.[citation needed] Brownlee cloned and expressed human clotting factor IX, providing a recombinant source of this protein for Haemophilia B patients...