receptor-associated protein is a protein that in humans is encoded by the GABARAP gene. Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated...
13 KB (1,678 words) - 16:38, 17 July 2025
antibodies also have antibodies that inhibit GABA-receptor-associated protein (GABARAP). Autoantibodies against amphiphysin and gephyrin are also sometimes found...
27 KB (2,962 words) - 07:24, 19 July 2025
eukaryotes. Even though there are homologues in animals (see for example GABARAP, GABARAPL1, GABARAPL2, MAP1LC3A, MAP1LC3B, MAP1LC3B2, and MAP1LC3C), this...
18 KB (2,085 words) - 18:55, 25 April 2024
substrates by ubiquitin. There are six principal mATG8s: LC3A, LC3B, LC3C, GABARAP, GABARAPL1 and GABARAPL2. Together, they comprise a sub-class of ubiquitin-like...
16 KB (1,693 words) - 16:37, 17 July 2025
(GATE-16); and (iii) γ-amino-butyric acid receptor-associate protein (GABARAP). MAP1LC3B is one of the four genes in the MAP1LC3 subfamily (others include...
40 KB (1,799 words) - 17:52, 16 July 2025
Yamamoto A, Oshitani-Okamoto S, Ohsumi Y, Yoshimori T (June 2004). "LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation"...
79 KB (9,285 words) - 18:49, 4 May 2025
PMID 15489334. Kabeya Y, Mizushima N, Yamamoto A, et al. (2005). "LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation"...
4 KB (460 words) - 16:15, 17 July 2025
variants encoding different isoforms. GABRG2 has been shown to interact with GABARAP and Dopamine receptor D5. GABAA receptor GRCh38: Ensembl release 89: ENSG00000113327...
11 KB (1,412 words) - 04:11, 15 July 2025
exposure of the TfR binding antibody. TfR1 has been shown to interact with GABARAP and HFE. CD71 is a robust immunohistochemistry marker for chorionic villi...
9 KB (957 words) - 07:34, 15 July 2025
complex (E3 for short) acts as a ubiquitin-like E3 enzyme, promoting LC3/GABARAP proteins anchoring to the AP membrane. LC3 is cleaved by ATG4 protease...
11 KB (1,271 words) - 03:03, 7 June 2025
formation: (i) the ULK1-ATG13-FIP200/RB1CC1 complex associates with the LC3B/GABARAP conjugation machinery through direct interactions between FIP200/RB1CC1...
120 KB (12,701 words) - 22:15, 10 July 2025
Olsen R, Triller A, Moss SJ (Jul 2001). "The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in...
14 KB (1,751 words) - 06:40, 19 July 2025
this protein interacts with COA1, SCO1, COX16, TTC19, DTX2, NADSYN1, GABARAP, AIFM1, COX4I1, CD81, COX14, SFXN1, and PLGRKT. GRCh38: Ensembl release...
11 KB (1,247 words) - 07:54, 3 December 2023
degradation. K63 ubiquitination is thought to recruit autophagy adaptors LC3/GABARAP which will then lead to mitophagy. It is still unclear which proteins are...
34 KB (4,152 words) - 09:40, 17 June 2025
HGNC:14458 Q9UQC2 5954 GAB3 HGNC:17515 Q8WWW8 5955 GAB4 HGNC:18325 Q2WGN9 5956 GABARAP HGNC:4067 O95166 5957 GABARAPL1 HGNC:4068 Q9H0R8 5958 GABARAPL2 HGNC:13291...
277 KB (17 words) - 09:51, 23 June 2025
EEF2 ENST00000309311 Eukaryotic translation elongation factor 2 chr19 GABARAP ENST00000577035 GABA type A receptor-associated protein chr17 PFDN5 ENST00000334478...
5 KB (486 words) - 19:42, 11 September 2022
Jouvenot M, Delage-Mourroux R (2003). "Expression of gec1/GABARAPL1 versus GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system"...
4 KB (611 words) - 22:28, 2 December 2023
field of selective autophagy, recognizing the enormous impact of the LC3/GABARAP signaling network displaying striking mechanistic similarities to ubiquitin...
14 KB (1,103 words) - 22:16, 20 September 2024
Standley, DM; Yoshimori, T; Yamamoto, M (August 2017). "Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense"...
20 KB (1,760 words) - 04:39, 11 January 2025
Betin VM, Lane JD (July 2009). "Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis". Journal...
3 KB (326 words) - 10:16, 9 June 2025
human Atg8 homologues, microtubule-associated protein light chain 3 (LC3), GABARAP, and GATE-16. The rapid advancement in our understanding of the mechanisms...
2 KB (225 words) - 08:07, 12 March 2021
to interact with gamma-aminobutyric acid receptor-associated protein (GABARAP) and microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A, or...
9 KB (1,095 words) - 17:52, 16 July 2025
specificity and interaction domain between GABA(A) receptor-associated protein (GABARAP) and GABA(A) receptors". J. Neurochem. 80 (5): 815–823. doi:10.1046/j.0022-3042...
4 KB (593 words) - 21:43, 15 July 2025
Bonn F, et al. (January 2020). "TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease". EMBO Reports. 21...
21 KB (2,314 words) - 22:22, 15 July 2025
been shown to interact with Raptor, Beclin1, Class-III-PI3K, GABARAPL2, GABARAP, SYNGAP1 and SDCBP. ULK1 is a 112-kDa protein. It contains a N-terminal...
17 KB (1,930 words) - 22:26, 15 July 2025
specificity and interaction domain between GABA(A) receptor-associated protein (GABARAP) and GABA(A) receptors". J. Neurochem. 80 (5): 815–823. doi:10.1046/j.0022-3042...
7 KB (897 words) - 21:54, 2 December 2023
homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p". The...
22 KB (2,808 words) - 09:48, 15 April 2024
Judith D, Tooze SA (2015). "Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130". Molecular...
14 KB (1,705 words) - 21:44, 15 July 2025
this by first localizing to the ER membrane---this it does by binding to GABARAP which binds ER, and through its Phox homology domain, which has a high...
14 KB (1,849 words) - 18:11, 17 July 2025
phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16". J. Biol. Chem. 281 (6): 3017–24. doi:10.1074/jbc.M505888200...
9 KB (1,150 words) - 04:25, 15 July 2025