system serves as a complex signaling switch for G protein-coupled receptors. GRK5 and the closely related GRK6 phosphorylate receptors at sites that encourage...
16 KB (1,986 words) - 20:33, 27 March 2024
the Ser/Thr protein kinase family, and is most highly similar to GRK4 and GRK5. The protein phosphorylates the activated forms of G protein-coupled receptors...
15 KB (1,750 words) - 20:34, 27 March 2024
elevated GRK5-mediated desensitization of airway beta2-adrenergic receptors, a drug target in asthma. In zebrafish and in humans, loss of GRK5 function...
18 KB (2,053 words) - 11:50, 28 December 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
45 KB (4,671 words) - 10:15, 22 May 2025
purification, and characterization of the G protein-coupled receptor kinase GRK5". The Journal of Biological Chemistry. 269 (2): 1099–1105. doi:10...
19 KB (2,093 words) - 07:08, 10 May 2025
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
69 KB (7,807 words) - 19:19, 19 September 2024
and trafficking rather than arrestin-mediated signaling (in contrast to GRK5 and GRK6, which have the opposite effect). This difference is one basis for...
14 KB (1,637 words) - 11:17, 19 June 2022
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
65 KB (7,149 words) - 18:25, 23 May 2025
HGNC:289 P25098 6652 GRK3 HGNC:290 P35626 6653 GRK4 HGNC:4543 P32298 6654 GRK5 HGNC:4544 P34947 6655 GRK6 HGNC:4545 P43250 6656 GRK7 HGNC:17031 Q8WTQ7 6657...
277 KB (17 words) - 18:41, 6 October 2024
kinase subfamily of the Ser/Thr protein kinase family, and is most similar to GRK5 and GRK6. G protein-coupled receptor kinases phosphorylate activated G protein-coupled...
7 KB (936 words) - 02:51, 28 March 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
4 KB (526 words) - 21:54, 3 March 2023
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
14 KB (1,385 words) - 10:32, 28 April 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
27 KB (2,665 words) - 16:53, 12 May 2025
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
14 KB (1,626 words) - 20:50, 30 May 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
50 KB (5,806 words) - 05:47, 25 May 2025
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
10 KB (1,233 words) - 11:39, 4 March 2023
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
46 KB (5,510 words) - 21:54, 29 November 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
11 KB (1,381 words) - 08:33, 30 November 2023
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
12 KB (1,456 words) - 16:56, 11 December 2023
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
7 KB (808 words) - 14:27, 17 December 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
35 KB (3,823 words) - 10:07, 12 May 2025
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
30 KB (3,340 words) - 01:47, 26 March 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
6 KB (756 words) - 14:59, 30 May 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
14 KB (1,447 words) - 09:31, 22 December 2023
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
120 KB (12,683 words) - 03:26, 29 May 2025
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
25 KB (2,896 words) - 12:38, 29 August 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
9 KB (1,180 words) - 04:07, 1 January 2024
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
3 KB (405 words) - 18:37, 29 September 2022
receptor kinase-2 G-protein coupled receptor kinases (EC 2.7.11.16) GRK4 GRK5 GRK6 Ca2+/calmodulin-dependent (EC 2.7.11.17) BRSK2 CAMK1 CAMK1A CAMK1B CAMK1D...
8 KB (886 words) - 12:46, 31 January 2024
FGR ; FLT1 ; FLT3 ; FLT4 ; FRK ; FYN ; GAK ; GRK1 ; GRK2 ; GRK3 ; GRK4 ; GRK5 ; GRK6 ; GRK7 ; GSG2 ; GSK3A ; GSK3B ; GUCY2C ; GUCY2D ; GUCY2F ; HCK ; HIPK1 ;...
17 KB (1,562 words) - 22:44, 26 May 2025