GTP cyclohydrolases are enzymes that catalyze imidazole ring opening of guanosine triphosphate (GTP). This reaction is the committed step in the biosynthesis...
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In enzymology, a GTP cyclohydrolase II (EC 3.5.4.25) is an enzyme that catalyzes the chemical reaction GTP + 3 H2O ⇌ {\displaystyle \rightleftharpoons...
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hydrolysis of GTP by GTP cyclohydrolase II. Alternatively two separate enzymes can carry out this reaction, initially GTP cyclohydrolase IIa hydrolyses...
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and ribA (GTP cyclohydrolase II) all reside in the lux operon. RibB is sometimes found as a bifunctional enzyme with GTP cyclohydrolase II that catalyses...
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List of EC numbers (EC 3) (section 3.6.5: Acting on GTP to facilitate cellular and subcellular movement)
GTP cyclohydrolase II EC 3.5.4.26: diaminohydroxyphosphoribosylaminopyrimidine deaminase EC 3.5.4.27: methenyltetrahydromethanopterin cyclohydrolase EC...
119 KB (15,563 words) - 19:44, 6 May 2025
Sapropterin is indicated in tetrahydrobiopterin deficiency caused by GTP cyclohydrolase I (GTPCH) deficiency, or 6-pyruvoyltetrahydropterin synthase (PTPS)...
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in the riboflavin biosynthesis pathway. It is formed from GTP by the enzyme GTP cyclohydrolase IIa which catalyzes the hydrolysis of the 8,9 bond in the...
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Retrieved 2018-03-09. Thöny B, Blau N (1997). "Mutations in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes". Human Mutation...
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the thesis labelled "The relationship of gene variation encoding GTP cyclohydrolase with the function of vascular endothelium in patients with type 2...
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retardation phalangeal hypoplasia Grubben–Decock–Borghgraef syndrome GTP cyclohydrolase deficiency Guanidinoacetate methyltransferase deficiency Guérin–Stern...
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Hyperphenylalaninemia due to GTP cyclohydrolase deficiency Hyperphenylalaninemic embryopathy Hyperpipecolatemia Hyperprolactinemia Hyperprolinemia type II Hyperprolinemia...
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PMID 12604615. Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j...
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translationally. All known folE RNAs are present upstream of genes encoding GTP cyclohydrolase I, which performs a step in folate metabolism. folE RNAs have been...
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Ringelstetter L, Müller C, Zandkarimi F, et al. (January 2020). "GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling"...
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aromatic amino acid dopa decarboxylase, tyrosine hydroxylase and GTP-cyclohydrolase 1, to the striatum in the brain, reprogramming transduced cells to...
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polymorphisms in GCH1 (GTP cyclohydrolase I) and ChAT (choline acetyltransferase) affect AD susceptibility in East Asians. GTP cyclohydrolase I is an enzyme that...
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Forkhead box B1 GATM: Glycine aminotransferase, mitochondrial GCHFR: GTP cyclohydrolase 1 feedback regulatory protein GLC1I: encoding protein Glaucoma 1,...
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PMID 1883349. Thöny B, Heizmann CW, Mattei MG (March 1995). "Human GTP-cyclohydrolase I gene and sepiapterin reductase gene map to region 14q21-q22 and...
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1159/000163662. PMID 1883524. Thöny B, Blau N (1997). "Mutations in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes". Hum. Mutat. 10...
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Category:EC 3.5.4 (In cyclic amidines) Adenosine deaminase (EC 3.5.4.4) GTP cyclohydrolase I (EC 3.5.4.16) Category:EC 3.5.5 (In nitriles) Nitrilase (EC 3.5...
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tb10446.x. PMID 3536512. Thöny B, Heizmann CW, Mattei MG (1995). "Human GTP-cyclohydrolase I gene and sepiapterin reductase gene map to region 14q21-q22 and...
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PMID 16710414. Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j...
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Retrieved 16 June 2019. Thöny B; Blau N (1997). "Mutations in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes". Hum. Mutat. 10...
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151.300 – gtp cyclohydrolase MeSH D08.811.277.151.350 – guanine deaminase MeSH D08.811.277.151.418 – methenyltetrahydrofolate cyclohydrolase MeSH D08.811...
158 KB (15,232 words) - 06:41, 8 March 2024