protein kinase 2 is an enzyme that in humans is encoded by the HIPK2 gene. HIPK2 can be categorized as a Serine/Threonine Protein kinase, specifically...
33 KB (3,894 words) - 01:47, 10 March 2024
of a recent study showing that CREB-binding protein is phosphorylated by HIPK2.) In plant physiology, autoradiography can be used to determine sugar accumulation...
13 KB (1,580 words) - 12:02, 13 January 2025
DAXX is then phosphorylated by homeodomain-interacting protein kinase 2 (HIPK2), which then activates apoptosis signal-inducing kinase 1 (ASK1), which...
67 KB (8,184 words) - 08:20, 28 December 2024
(2001). "Isolation and characterization of cDNAs for the protein kinase HIPK2". Biochim. Biophys. Acta. 1518 (1–2): 168–72. doi:10.1016/S0167-4781(00)00308-0...
14 KB (1,210 words) - 13:35, 14 June 2024
been used to uncover the phosphorylation of the protein CBP by the kinase HIPK2 Another comprehensive approach is site saturation mutagenesis where one...
25 KB (2,980 words) - 11:45, 6 February 2025
EIF2AK2, ELL, EP300, ERCC6, GNL3, GPS2, GSK3B, HSP90AA1, HIF1A, HIPK1, HIPK2, HMGB1, HSPA9, Huntingtin, ING1, ING4, ING5, IκBα, KPNB1, LMO3, Mdm2, MDM4...
131 KB (14,361 words) - 06:05, 20 May 2025
HGNC:4913 O00291 7071 HIP1R HGNC:18415 O75146 7072 HIPK1 HGNC:19006 Q86Z02 7073 HIPK2 HGNC:14402 Q9H2X6 7074 HIPK3 HGNC:4915 Q9H422 7075 HIPK4 HGNC:19007 Q8NE63...
277 KB (17 words) - 18:41, 6 October 2024
role in carcinogenesis of gall bladder cancer Degradation of endogenous HIPK2 depends on the presence of a functional p53 protein. p53 codon 72 alleles...
4 KB (564 words) - 14:57, 20 September 2022
Kim Y (2005). "Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease...
10 KB (1,307 words) - 21:50, 7 October 2024
domain of Mdm2 may stimulate its ability to target p53 for degradation. HIPK2 is a protein that regulates Mdm2 in this way. The induction of the p14arf...
34 KB (4,010 words) - 17:12, 19 August 2024
Y, Schmitz ML, Koseki H, Kitabayashi I (Sep 2006). "Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel...
3 KB (419 words) - 15:12, 31 July 2023
Some kind of positive feedback system was also discovered; JNK activates HIPK2, which stands for the translocation of nuclear Daxx to the cytoplasm. In...
11 KB (1,528 words) - 20:53, 21 December 2023
or "stress inducible protein". TP53INP1 has been shown to interact with HIPK2 and p53. GRCh38: Ensembl release 89: ENSG00000164938 – Ensembl, May 2017...
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found 69 orthologous circRNAs. For example, both humans and mice encode the HIPK2 and HIPK3 genes, two paralogous kinases which produce a large amount of...
56 KB (6,708 words) - 20:49, 30 April 2025
"The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions". EMBO J. 29 (22): 3750–61. doi:10.1038/emboj...
6 KB (729 words) - 21:52, 26 November 2023
GRK7 ; GSG2 ; GSK3A ; GSK3B ; GUCY2C ; GUCY2D ; GUCY2F ; HCK ; HIPK1 ; HIPK2 ; HIPK3 ; HIPK4 ; HUNK ; ICK ; IGF1R ; IKBKB ; IKBKE ; ILK ; INSR ; INSRR ;...
17 KB (1,562 words) - 23:49, 23 December 2024
signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK". Genes Dev. 18 (7): 816–29. doi:10.1101/gad.1170604. PMC 387421...
8 KB (1,051 words) - 05:58, 17 June 2024
with: Androgen receptor, C-Met, DISC1, DYRK1B, Glucocorticoid receptor, HIPK2 MKLN1, S100A7, and USP11. GRCh38: Ensembl release 89: ENSG00000010017 –...
10 KB (1,266 words) - 12:46, 7 September 2023
for activation of PGE of Aire-dependent TRAs. Worth mentioning is also Hipk2, which phosphorylates Aire and CBP however, its absence affects mostly PGE...
30 KB (3,538 words) - 08:56, 19 March 2024
(InterPro: IPR003380, IPR023216. SKI protein has been shown to interact with: HIPK2, MECP2, Mothers against decapentaplegic homolog 1 and Mothers against decapentaplegic...
20 KB (2,418 words) - 01:54, 22 December 2023
shock modulates the subcellular localization, stability, and activity of HIPK2". Biochemical and Biophysical Research Communications. 472 (4): 580–584...
15 KB (1,244 words) - 07:57, 12 May 2024