• Hedonic sensitization is a neuropsychological process in which repeated exposure to a rewarding stimulus leads to a heightened hedonic or motivational...
    9 KB (867 words) - 03:33, 12 July 2025
  • The hedonic treadmill functions similarly to most adaptations that serve to protect and enhance perception. In the case of hedonics, the sensitization or...
    32 KB (3,797 words) - 17:40, 18 July 2025
  • Thumbnail for Reward system
    Carrot and stick Compliance (psychology) Experience machine Frisson Hedonic sensitization Motivation Norm of reciprocity Wirehead (science fiction) Schultz...
    106 KB (13,101 words) - 12:50, 11 July 2025
  • from both hedonic adaptation, which refers to the return to a stable baseline level of happiness following change, and hedonic sensitization, wherein emotional...
    6 KB (680 words) - 04:21, 10 July 2025
  • Thumbnail for Addiction
    bidirectional reward cross-sensitization effect that is mediated through ΔFosB. In contrast to ΔFosB's reward-sensitizing effect, CREB transcriptional...
    206 KB (23,805 words) - 20:22, 18 July 2025
  • called the Incentive Sensitization Theory of Addiction. According to this theory, drug addiction develops from a sensitization of the mesolimbic dopamine...
    6 KB (605 words) - 14:28, 2 September 2024
  • of sensitization. Animals tested in a novel drug context often failed to express behavioral sensitization, termed context-specific sensitization. Simultaneously...
    30 KB (3,101 words) - 20:13, 18 July 2025
  • (pleasure or hedonic value) of a drug or other stimulus becomes dissociated from "wanting" (i.e., desire or craving) due to the sensitization of incentive...
    23 KB (3,234 words) - 08:22, 7 February 2024
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    substance P directly causes acute sensitization. Instead, substance P may contribute to itch by increasing neuronal sensitization and may affect release of mast...
    35 KB (3,831 words) - 14:24, 22 July 2025
  • Drug liking is a measure of the pleasurable (hedonic) experience when a person consumes drugs. It is commonly used to study the misuse liability of drugs...
    6 KB (639 words) - 11:59, 9 February 2025
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    PMID 32694734. S2CID 219933429. Lustig RH (September 2010). "Fructose: metabolic, hedonic, and societal parallels with ethanol". Journal of the American Dietetic...
    138 KB (15,252 words) - 07:38, 15 July 2025
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    pleasure, and released in areas of the brain called hedonic hotspots (or pleasure centers). Hedonic hotspots are located in the nucleus accumbens, the...
    20 KB (4,307 words) - 18:03, 21 July 2025
  • Thumbnail for Dopamine
    detailed studies have shown that dopamine cannot simply be equated with hedonic "liking" or pleasure, as reflected in the consummatory behavioral response...
    140 KB (14,360 words) - 16:35, 10 July 2025
  • whereas the sensitization process is incremental enhancing the tendency to respond. Thus when the habituation process exceeds the sensitization process behavior...
    43 KB (5,570 words) - 22:54, 21 July 2025
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    2013). ... However, hedonic effects might well change over time. As a drug was taken repeatedly, mesolimbic dopaminergic sensitization could consequently...
    77 KB (10,078 words) - 04:45, 18 June 2025
  • 2013). ... However, hedonic effects might well change over time. As a drug was taken repeatedly, mesolimbic dopaminergic sensitization could consequently...
    71 KB (9,129 words) - 23:42, 17 July 2025
  • October 2024. Koob GF (May 1996). "Drug addiction: the yin and yang of hedonic homeostasis". Neuron. 16 (5): 893–6. doi:10.1016/S0896-6273(00)80109-9...
    12 KB (1,606 words) - 16:24, 17 July 2025
  • Thumbnail for Nucleus accumbens
    et al., 2009), and sexual experience causes sensitized drug-related behaviors, including cross-sensitization to amphetamine (Amph)-induced locomotor activity...
    80 KB (9,803 words) - 17:40, 17 July 2025
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    mesocorticolimbic dopamine) and "liking" a reward (i.e. pleasure, tied to hedonic hotspots), aspects which are dissociable. People can be addicted to drugs...
    127 KB (14,728 words) - 02:07, 24 July 2025
  • impulsiveness and behavioral inhibition, and an impulsivity model of reward sensitization and impulsiveness. Research has consistently shown strong associations...
    31 KB (3,797 words) - 01:31, 25 June 2025
  • ayahuasca on the development of ethanol-induced behavioral sensitization and on a post-sensitization treatment in mice". Physiology & Behavior. 142: 28–36...
    63 KB (7,364 words) - 18:51, 11 July 2025
  • pleasure, and released in areas of the brain called hedonic hotspots (or pleasure centers). Hedonic hotspots are located in the nucleus accumbens, the...
    103 KB (11,340 words) - 02:02, 24 July 2025
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    their own, may potentiate the positive hedonic efficacy of acute drug intoxication and reduce the negative hedonic consequences of drug withdrawal. Salerno...
    199 KB (19,559 words) - 19:23, 23 July 2025
  • Thumbnail for Orexin
    "Neurobiology of the Orexin System and Its Potential Role in the Regulation of Hedonic Tone". Brain Sciences. 12 (2): 150. doi:10.3390/brainsci12020150. PMC 8870430...
    54 KB (6,158 words) - 19:50, 15 July 2025
  • Thumbnail for Short-term effects of alcohol consumption
    effects later in a drinking episode as BAC wanes. The combined influence of hedonic and aversive subjective experiences over the course of a drinking session...
    57 KB (6,414 words) - 17:28, 18 July 2025
  • self-administration. Science, 1989, 245, 1511–1513. Koob G.F., Le Moal M. Drug abuse : hedonic homeostatis dysregulation. Science, 1997, 278, 52–58. Cabib S., Orsini...
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  • Thumbnail for Dopamine receptor
    Berridge KC, Robinson TE (1998). "What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?". Brain Research. Brain...
    54 KB (5,640 words) - 20:34, 17 July 2025
  • Roberts, Tom L. (2013). "Taking 'fun and games' seriously: Proposing the hedonic-motivation system adoption model (HMSAM)". Journal of the Association for...
    111 KB (14,413 words) - 21:01, 13 July 2025
  • Thumbnail for Pain
    by life and death. Feeling, a perceptual state of conscious experience. Hedonic adaptation, the tendency to quickly return to a relatively stable level...
    104 KB (11,521 words) - 11:00, 18 July 2025