A helix bundle is a small protein fold composed of several alpha helices that are usually nearly parallel or antiparallel to each other. Three-helix bundles...

An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix). The alpha helix is the most common structural...

{\displaystyle \alpha } -helix bundle, where one α {\displaystyle \alpha } -helix is contributed by syntaxin 1, one α {\displaystyle \alpha } -helix by synaptobrevin...

crystallize bHLH proteins bound to E-boxes, demonstrating that the parallel 4-helix bundle motif loop orients the basic sequences to interact with specific nucleotides...

the C-terminus consisting of a fast and independently folding three-helix bundle that is stabilized by hydrophobic interactions. The headpiece domain...

as an alpha helix and exists as an uncoiled strand. Helices that cover the inner membrane line the channel. These also form a 6 helix bundle that signifies...

of a helix hairpin is unknown; however, a four helix bundle is composed of two helix hairpins, which have important ligand binding sites. A helix corner...

two different architectures, both composed of a four-helix bundle but differing in the way the bundle is assembled. Most structurally characterized HPt proteins...

Dutton PL (1998). "A designed cavity in the hydrophobic core of a four-α-helix bundle improves volatile anesthetic binding affinity". Biochemistry. 37 (5):...

Structurally, Rop is a homodimeric four-helix bundle protein formed by the antiparallel interaction of two helix-turn-helix monomers. The Rop protein's structure...

Robertson DE, DeGrado WF (1994-02-01). "Design of a heme-binding four-helix bundle". Journal of the American Chemical Society. 116 (3): 856–865. doi:10...

composed of five homologous Ig-binding domains that fold into a three-helix bundle. Each domain is able to bind proteins from many mammalian species, most...

major capsid protein (MCP) that contains the SIRV2 fold, a type of alpha-helix bundle containing four helices. The virion consists of the genome encased in...

parallel 4 helix bundle. This bundle marks the BamHI dimer interface, and it is thought that the dipole moments of the NH2-terminal atoms on this bundle may...

fold, a type of alpha-helix bundle, and the MCPs of bicaudaviruses possess the ATV-like fold, another type of alpha-helix bundle. The architectural classes...

of IL2 comprises a bundle of 4 helices (termed A-D), flanked by 2 shorter helices and several poorly defined loops. Residues in helix A, and in the loop...

Helix-turn-helix is a DNA-binding domain (DBD). The helix-turn-helix (HTH) is a major structural motif capable of binding DNA. Each monomer incorporates...

hydroxyproline. Collagen folded into a triple helix is known as tropocollagen. Collagen triple helices are often bundled into fibrils which themselves form larger...

and more recently the plakin family. The spectrin repeat forms a three-helix bundle. These conform to the rules of the heptad repeat. Spectrin repeats give...

composed of alpha helices and lack disulfide bridges. The parent three-helix bundle structure is currently the fastest folding protein structure known. Specific...

significantly steeper than other helical packings such as the helix bundle. The exact angle of helix packing depends on the sequence of the protein, because...

formed following the conformational change in gp41 that creates the six-helix bundle. These pockets could potentially serve as targets for small molecule...

cells. Inositol hexaphosphate also facilitates the formation of the six-helix bundle and assembly of the immature HIV-1 Gag lattice. IP6 makes ionic contacts...

solved to atomic resolution, confirming the predicted long chain four helix bundle topology. Comparing this structure with the known structures of other...

active sites with each domain preceded by a regulatory three helix bundle. These helical bundles contain important histidine residues that play a role in...

hinge helix, which is important for allosteric communication) A C-terminal tetramerization region (which joins four monomers in an alpha-helix bundle) DNA...

colony-stimulating factor determined by NMR spectroscopy. Loop mobility in a four-helix-bundle protein". Biochemistry. 33 (28): 8453–8463. doi:10.1021/bi00194a009....

most common tertiary structures of these proteins are transmembrane helix bundle and beta barrel. The portion of the membrane proteins that are attached...

binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold". FEBS J. 275 (11): 2668–76. doi:10.1111/j.1742-4658.2008.06438...

disulphide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist. The helices are anti-parallel, with 2 overhand...