Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
59 KB (6,731 words) - 05:32, 23 May 2025
Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
23 KB (2,623 words) - 08:53, 15 March 2025
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
29 KB (3,358 words) - 23:42, 16 March 2025
epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 01:06, 1 March 2025
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 14:24, 24 February 2025
Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
10 KB (1,131 words) - 18:45, 6 May 2025
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 14:53, 16 April 2025
nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3...
37 KB (4,235 words) - 04:17, 19 March 2025
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,844 words) - 17:02, 8 May 2025
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
13 KB (1,563 words) - 09:00, 13 March 2024
through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular...
6 KB (596 words) - 06:45, 1 January 2025
VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
8 KB (754 words) - 13:03, 18 September 2024
Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
40 KB (4,578 words) - 12:30, 10 September 2024
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
27 KB (3,110 words) - 06:33, 25 May 2025
The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
29 KB (3,603 words) - 16:26, 25 May 2024
is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
34 KB (4,512 words) - 06:26, 2 May 2025
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...
67 KB (8,184 words) - 08:20, 28 December 2024
and ketogenesis. FGF21 stimulates phosphorylation of fibroblast growth factor receptor substrate 2 and ERK1/2 in the liver. Acute FGF21 treatment induced...
24 KB (3,038 words) - 23:40, 29 November 2024
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 15:04, 24 May 2025
The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
14 KB (1,689 words) - 01:31, 19 August 2024
fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor. Members...
25 KB (3,126 words) - 10:38, 23 January 2025
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
28 KB (3,078 words) - 17:48, 25 January 2025
A growth factor receptor is a receptor that binds to a growth factor. Growth factor receptors are the first stop in cells where the signaling cascade...
5 KB (591 words) - 23:31, 23 May 2025
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,716 words) - 11:48, 25 May 2025
Growth factor receptor inhibitors (growth factor inhibitors, growth factor receptor blockers, growth factor blockers, growth factor receptor antagonists...
4 KB (389 words) - 04:03, 24 May 2025
Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
14 KB (1,745 words) - 09:02, 15 July 2024
growth factors such as epidermal growth factor (EGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), hepatocyte growth factor (HGF)...
22 KB (2,480 words) - 14:02, 24 March 2025
Crizotinib (category Receptor tyrosine kinase inhibitors)
cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the oncogenesis...
22 KB (1,866 words) - 14:24, 23 May 2025
exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. In their active form, the majority of TNF receptors form trimeric...
9 KB (610 words) - 13:48, 14 January 2025
Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Two...
5 KB (670 words) - 10:25, 10 April 2025