• Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
    59 KB (6,731 words) - 05:32, 23 May 2025
  • Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,623 words) - 08:53, 15 March 2025
  • Thumbnail for Platelet-derived growth factor receptor A
    Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
    29 KB (3,358 words) - 23:42, 16 March 2025
  • Thumbnail for Epidermal growth factor receptor
    epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 01:06, 1 March 2025
  • Thumbnail for Fibroblast growth factor receptor 1
    Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
    44 KB (5,003 words) - 14:24, 24 February 2025
  • Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
    10 KB (1,131 words) - 18:45, 6 May 2025
  • The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
    8 KB (827 words) - 14:53, 16 April 2025
  • Thumbnail for Low-affinity nerve growth factor receptor
    nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3...
    37 KB (4,235 words) - 04:17, 19 March 2025
  • Thumbnail for Fibroblast growth factor receptor 3
    Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
    17 KB (1,844 words) - 17:02, 8 May 2025
  • Thumbnail for Platelet-derived growth factor receptor
    Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular...
    6 KB (596 words) - 06:45, 1 January 2025
  • Thumbnail for VEGF receptor
    VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
    8 KB (754 words) - 13:03, 18 September 2024
  • Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
    40 KB (4,578 words) - 12:30, 10 September 2024
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    27 KB (3,110 words) - 06:33, 25 May 2025
  • Thumbnail for Insulin-like growth factor 1 receptor
    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
    29 KB (3,603 words) - 16:26, 25 May 2024
  • Thumbnail for Insulin-like growth factor 1
    is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
    34 KB (4,512 words) - 06:26, 2 May 2025
  • Thumbnail for Transforming growth factor beta
    Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...
    67 KB (8,184 words) - 08:20, 28 December 2024
  • Thumbnail for Fibroblast growth factor 21
    and ketogenesis. FGF21 stimulates phosphorylation of fibroblast growth factor receptor substrate 2 and ERK1/2 in the liver. Acute FGF21 treatment induced...
    24 KB (3,038 words) - 23:40, 29 November 2024
  • Thumbnail for Platelet-derived growth factor
    Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
    24 KB (2,882 words) - 15:04, 24 May 2025
  • Thumbnail for Insulin-like growth factor
    The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
    14 KB (1,689 words) - 01:31, 19 August 2024
  • fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor. Members...
    25 KB (3,126 words) - 10:38, 23 January 2025
  • Thumbnail for Receptor tyrosine kinase
    Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
    28 KB (3,078 words) - 17:48, 25 January 2025
  • A growth factor receptor is a receptor that binds to a growth factor. Growth factor receptors are the first stop in cells where the signaling cascade...
    5 KB (591 words) - 23:31, 23 May 2025
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,716 words) - 11:48, 25 May 2025
  • Growth factor receptor inhibitors (growth factor inhibitors, growth factor receptor blockers, growth factor blockers, growth factor receptor antagonists...
    4 KB (389 words) - 04:03, 24 May 2025
  • Thumbnail for Fibroblast growth factor receptor 2
    Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
    14 KB (1,745 words) - 09:02, 15 July 2024
  • Thumbnail for Cell surface receptor
    growth factors such as epidermal growth factor (EGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), hepatocyte growth factor (HGF)...
    22 KB (2,480 words) - 14:02, 24 March 2025
  • Thumbnail for Crizotinib
    Crizotinib (category Receptor tyrosine kinase inhibitors)
    cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the oncogenesis...
    22 KB (1,866 words) - 14:24, 23 May 2025
  • Thumbnail for TNF receptor superfamily
    exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. In their active form, the majority of TNF receptors form trimeric...
    9 KB (610 words) - 13:48, 14 January 2025
  • Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Two...
    5 KB (670 words) - 10:25, 10 April 2025