• The heptad repeat is an example of a structural motif that consists of a repeating pattern of seven amino acids: a b c d e f g H P P H C P C where H represents...
    2 KB (237 words) - 06:22, 26 April 2024
  • Heptad (chord), heptachord in music (set) Heptad (computing), a group of 7 bits in computing Heptad repeat, a structural motif in proteins L'Heptade,...
    548 bytes (104 words) - 14:45, 5 February 2025
  • Coiled coil (category Protein tandem repeats)
    charged (c) amino-acid residues, referred to as a heptad repeat. The positions in the heptad repeat are usually labeled abcdefg, where a and d are the...
    34 KB (3,933 words) - 15:57, 23 May 2025
  • Thumbnail for Coronavirus spike protein
    enter and destabilize the host cell membrane. S2 also contains two heptad repeat subdomains known as HR1 and HR2, sometimes called the "fusion core"...
    75 KB (7,321 words) - 04:11, 1 July 2025
  • Thumbnail for Lamin
    Lamins have a unique structure of the heptad repeats that is continuous in nature and contains an additional six heptads. While the head domain of lamins is...
    18 KB (2,198 words) - 02:12, 10 March 2025
  • Thumbnail for COVID-19
    the virus to its potential cell host via the H1 and HR2, which are heptad repeat regions. Studies have shown that S1 domain induced IgG and IgA antibody...
    288 KB (32,869 words) - 18:17, 23 June 2025
  • drug that must be injected and acts by interacting with the N-terminal heptad repeat of gp41 of HIV to form an inactive hetero six-helix bundle, therefore...
    134 KB (15,792 words) - 01:59, 22 June 2025
  • Thumbnail for Leucine zipper
    leucine zippers, leucines are predominant at the d position of the heptad repeat. These residues pack against each other every second turn of the alpha-helices...
    16 KB (2,049 words) - 20:45, 24 May 2025
  • coiled together, each of which consists of a 7-residue repeat (a-b-c-d-e-f-g) called a heptad. Heptads are unique in that positions a, d are occupied by hydrophobic...
    23 KB (2,897 words) - 23:51, 22 May 2025
  • Thumbnail for Dynein
    from the stalk is pulled by the buttress, sliding the helix half a heptad repeat relative to its coilled-coil partner, and kinking the stalk. As a result...
    29 KB (3,321 words) - 14:12, 8 June 2025
  • Thumbnail for Alpha helix
    contain a highly characteristic sequence motif known as a heptad repeat, in which the motif repeats itself every seven residues along the sequence (amino...
    46 KB (5,204 words) - 14:05, 14 June 2025
  • Thumbnail for Spectrin repeat
    plakin family. The spectrin repeat forms a three-helix bundle. These conform to the rules of the heptad repeat. Spectrin repeats give rise to linear proteins...
    4 KB (396 words) - 04:30, 25 April 2025
  • Thumbnail for MFN2
    coiled-coil heptad-repeat (HR1) domain, a proline-rich (PR) region, two sequential transmembrane (TM) domains crossing the OMM and a second cytosolic heptad-repeat...
    28 KB (3,346 words) - 00:30, 18 June 2025
  • motifs like a glutamate rich region. The alpha domain is composed of heptad repeats of hydrophobic residues that aid the formation of a coiled coil structure...
    8 KB (974 words) - 18:12, 21 June 2025
  • Thumbnail for Syncytin-1
    the cell surface. Syncytin-1 TM contains the fusion peptide, and two heptad repeats separated by a chain reversal region common to class I retroviral glycoproteins...
    16 KB (2,024 words) - 01:49, 19 August 2024
  • Thumbnail for Tenascin C
    similar structural pattern. These similar modules include heptad repeats, EGF-like repeats, fibronectin type III domains, and a C-terminal globular domain...
    20 KB (2,565 words) - 04:57, 23 December 2023
  • Thumbnail for Gp41
    region (residues 512-527), the helical N-terminal heptad repeat (NHR) and C-terminal heptad repeat (CHR). In addition to these regions, there is also...
    14 KB (1,709 words) - 03:20, 12 March 2024
  • Thumbnail for SNARE protein
    called a SNARE motif that consists of 60-70 amino acids and contains heptad repeats that have the ability to form coiled-coil structures. V- and t-SNAREs...
    54 KB (6,597 words) - 21:12, 11 July 2025
  • Thumbnail for Pulmonary surfactant protein D
    Schumacher T, Wang H, Hu S, et al. (June 2001). "The amino-terminal heptad repeats of the coiled-coil neck domain of pulmonary surfactant protein d are...
    4 KB (470 words) - 00:54, 4 November 2024
  • Thumbnail for Keratin 5
    provide specificity to different IF polypeptides. IF central rods contain heptad repeats (repeating seven residue patterns) of hydrophobic resides that allow...
    22 KB (2,682 words) - 05:48, 12 July 2025
  • doi:10.1002/art.1780351216. PMID 1472129. Heptad Repeat 2 in Herpes Simplex Virus 1 gH Interacts with Heptad Repeat 1 and Is Critical for Virus Entry and...
    17 KB (1,624 words) - 22:44, 28 April 2025
  • Thumbnail for Krüppel associated box
    by six amino acids 5’ to the zinc finger region of KOX1/ZNF10 coined heptad repeat of leucines (also known as a leucine zipper). Later, this domain was...
    8 KB (935 words) - 12:49, 4 July 2025
  • Thumbnail for Alphabody
    α-helices, composed of four heptad repeats (stretches of 7 residues) each, connected via glycine/serine-rich linkers. The standard heptad sequence is "IAAIQKQ"...
    11 KB (1,123 words) - 11:36, 18 April 2020
  • Thumbnail for Coiled-coil domain containing 42B
    consists of two alpha helices wrapped around each other to form a twist. Heptad repeat pattern (abcdefg)n forms the sequence of coiled coil structure, where...
    26 KB (2,150 words) - 00:43, 29 June 2025
  • Thumbnail for EIF3M
    (June 2005). "A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins". J. Virol. 79 (12):...
    5 KB (597 words) - 00:26, 4 March 2023
  • Thumbnail for Avian metaavulavirus 2
    proteins and is directly involved in virus fusion. It is believed that two heptad repeat regions (HR1) and (HR2) form a six-helix bundle structure that helps...
    17 KB (1,989 words) - 07:29, 31 May 2025
  • (June 2005). "A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins". Journal of Virology...
    16 KB (1,491 words) - 19:59, 29 May 2025
  • Thumbnail for KTN1
    gene encoding a human leukocyte protein characterised by extensive heptad repeats". Gene. 144 (2): 221–8. doi:10.1016/0378-1119(94)90381-6. PMID 8039706...
    10 KB (1,254 words) - 16:10, 3 April 2024
  • Thumbnail for NDC80
    Lee WH (October 1997). "HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis". Molecular and Cellular Biology. 17...
    10 KB (1,178 words) - 15:32, 6 April 2024
  • Thumbnail for Mismatch repair endonuclease PMS2
    is located in residues 492-742. The interacting domains in PMS2 have heptad repeats that are characteristic of leucine zipper proteins. MLH1 interacts with...
    27 KB (3,253 words) - 03:52, 7 November 2024