A humanized mouse is a genetically modified mouse that has functioning human genes, cells, tissues and/or organs. Humanized mice are commonly used as...

human patients (see also Human anti-mouse antibody). Until 2021, the International Nonproprietary Names of new humanized antibodies ended in -zumab, as in...

from which he emerges in a flash as Super Mouse! He's no longer a tiny rodent, but a two-footed, humanized mouse with a massive chest and powerful biceps...

acquired immunodeficiency syndrome (AIDS) over time. Furthermore, humanized mouse models can also be used to test potential therapies for this disease...

choosing the correct "wild-type" control mouse to use for comparison are sometimes overlooked. Humanized mouse Singh, M.; Murriel, C. L.; Johnson, L. (16...

cells from a patient's tumor are implanted into an immunodeficient or humanized mouse. It is a form of xenotransplantation. PDX models are used to create...

Mouse universe is a fictional shared universe which is the setting for stories involving Disney cartoon characters, including Mickey and Minnie Mouse...

Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody, more specifically a PD-1 inhibitor, used in cancer immunotherapy that treats...

2016). "TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model". PLOS ONE. 11 (3): e0149093. Bibcode:2016PLoSO..1149093W. doi:10...

Mickey Mouse (originally known as Mickey Mouse Sound Cartoons) is a series of American animated comedy short films produced by Walt Disney Productions...

Medicine Hematology Humanized mouse Nude mouse SCID mouse M. Ito and, et al. (2002). "NOD/SCID/γnull mouse: an excellent recipient mouse model for engraftment...

Establishing a functional, humanized immune system from engrafted human hematopoietic stem cells and progenitors. Humanized models for studying human-specific...

human lung cell lines and prevent SARS-CoV-2 induced ARDS in an ACE2 humanized mouse model. Infused rhACE2 has been evaluated in clinical trials for the...

Idle JR, Gonzalez FJ (May 2004). "Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates". Drug Metabolism Reviews. 36 (2):...

circuits. Humanized FOXP2 mice display altered cortico-basal ganglia circuits. The human allele of the FOXP2 gene was transferred into the mouse embryos...

1856-1871.e6. doi: 10.1016/j.immuni.2022.07.020 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies...

Patrick S.; Xu, Zhenming; Zan, Hong; Casali, Paolo (August 2024). "A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody...

long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model". Nature Medicine. 25 (9): 1377–1384. doi:10.1038/s41591-019-0560-x...

endocrine-disrupting chemical research, these rodents are used to produce humanized mouse models. Additionally, scientists use gene knockout lines of mice in...

Clarabelle first appeared as a nonhumanized cow in the Mickey Mouse cartoon Plane Crazy in 1928. Humanized soon afterward, she appeared frequently in cartoons from...

human–animal hybrids mainly include humanized mice that have been genetically modified by xenotransplantation of human genes. Humanized mice are commonly used as...

2005). "Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models". Nature Cell Biology. 7 (7): 675–85. doi:10.1038/ncb1270. PMID 15965469...

vaccine development. Tsuji's team has also succeeded in establishing a humanized mouse model that mimics the human immune system, called HIS mice. He used...

tras-tu-zu-mab. Therefore, the drug is a humanized monoclonal antibody used against a tumor. Alacizumab pegol is a PEGylated humanized antibody targeting the circulatory...

Yamadera. Classified as an Electric-type Pokémon, Pikachu is a large yellow mouse with a lightning bolt-shaped tail, and red sacs on its cheek which can generate...

published over 180 peer-reviewed papers on HIV and HCV. His work used humanized mouse models to accelerate development and testing of novel immunotherapies...

sites and inadequately recruit host effector functions. Chimeric and humanized antibodies have generally replaced them in therapeutic antibody applications...

Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential. Journal of Virology. Volume 91. Issue...

the uncontrolled cell division. It has a humanized human-mouse h-R3 heavy chain and a humanized human-mouse h-R3 κ-chain. Nimotuzumab binds with optimal...

immunoglobulin E-mediated food allergy. Omalizumab is a recombinant DNA-derived humanized IgG1 monoclonal antibody which specifically binds to free human immunoglobulin...