Immunodeficiency with hyperimmunoglobulin M is a rare disorder characterized by recurrent infections, low or absent IgG, IgE, and IgA levels, and normal...

although more often only with immunodeficiency. Elevated IgE is the hallmark of HIES. An IgE level greater than 2,000 IU/mL is often considered diagnostic...

combined immunodeficiency (SCID) DiGeorge syndrome Hyperimmunoglobulin E syndrome (also known as Job's Syndrome) Common variable immunodeficiency (CVID):...

Hyper-IgM syndrome type 4 Hyper-IgM syndrome type 5 Hyperimmunoglobulin D syndrome Hyperimmunoglobulin E syndrome Hypermobility syndrome Hyperosmolar syndrome...

primary immunodeficiency diseases are sometimes associated with modest increases in eosinophil counts, i.e. eosinophilia. The hyperimmunoglobulin E syndrome...

DOCK8 deficiency, also called DOCK8 immunodeficiency syndrome, is the autosomal recessive form of hyperimmunoglobulin E syndrome, a genetic disorder characterized...

focuses on hyperimmunoglobulin E syndromes and immune disorders. Freeman earned a B.A. in biology from Carleton College in 1992. She received a M.D. degree...

mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES), a primary immunodeficiency characterized by elevated serum immunoglobulin...

eosinophilias (e.g. hyperimmunoglobulin E syndrome, Omenn syndrome), Wiskott–Aldrich syndrome, and numerous other primary immunodeficiency syndromes); and...

Holland SM, Schmitt M, Weiss M, Frosch M, Bergmann M, Davis J, Belohradsky BH, Grimbacher B (2004). "Autosomal recessive hyperimmunoglobulin E syndrome: a distinct...

are marked with a group of immunologic and neurologic impairments. Often patients present with similar manifestations to Hyperimmunoglobulin E syndrome...