• Thumbnail for Integrin-linked kinase
    Integrin-linked kinase is an enzyme that in humans is encoded by the ILK gene involved with integrin-mediated signal transduction. Mutations in ILK are...
    22 KB (2,662 words) - 16:37, 11 June 2025
  • Thumbnail for Integrin
    "Integrin alphaVbeta3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and...
    36 KB (3,928 words) - 22:54, 6 February 2025
  • Thumbnail for Signal transduction
    Signal transduction (category Commons category link is on Wikidata)
    molecules, the main coordinator being integrin-linked kinase. As shown in the adjacent picture, cooperative integrin-RTK signaling determines the timing...
    62 KB (7,645 words) - 05:36, 2 June 2025
  • Thumbnail for ILKAP
    Integrin-linked kinase-associated serine/threonine phosphatase 2C is an enzyme that in humans is encoded by the ILKAP gene. The protein encoded by this...
    3 KB (448 words) - 21:07, 3 March 2023
  • Thumbnail for Protein kinase B
    although other molecules, including integrin-linked kinase (ILK) and mitogen-activated protein kinase-activated protein kinase-2 (MAPKAPK2) can also serve as...
    35 KB (3,831 words) - 20:54, 25 May 2025
  • mediates cell survival in vitro via interaction with integrin beta 1 and activation of integrin-linked kinase. J. Biol. Chem. doi:10.1074/jbc.M706563200...
    4 KB (506 words) - 14:44, 8 June 2025
  • Thumbnail for AKT1
    AKT1 (category Protein kinases)
    "Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase". Proc. Natl. Acad...
    24 KB (2,818 words) - 09:21, 25 January 2025
  • ILK or Ilk may refer to: Integrin-linked kinase, protein-coding gene in the species Homo sapiens ilk, the ISO 639-3 code for Bugkalot language Ilkley railway...
    327 bytes (78 words) - 04:50, 20 December 2023
  • Thumbnail for LIMS1
    thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its...
    8 KB (1,101 words) - 18:16, 9 December 2024
  • Thumbnail for Phosphoinositide-dependent kinase-1
    2001). "Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine...
    18 KB (2,127 words) - 23:00, 19 June 2025
  • Thumbnail for Tyrosine-protein kinase SYK
    Andersson T, Dib K (March 2003). "Fgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human...
    18 KB (2,083 words) - 06:18, 25 December 2023
  • Thumbnail for PARVB
    PMID 10591208. Yamaji S, Suzuki A, Sugiyama Y, et al. (2001). "A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate...
    6 KB (725 words) - 11:42, 4 March 2023
  • Thumbnail for Transforming growth factor beta
    of integrins participating in latent TGF-β1 activation arose from studies that examined mutations/knockouts of β6 integrin, αV integrin, β8 integrin and...
    67 KB (8,184 words) - 21:42, 19 June 2025
  • Thumbnail for PARVA
    et al. (2001). "A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading". J. Cell Biol. 153 (3):...
    5 KB (680 words) - 07:18, 29 December 2023
  • Thumbnail for Integrin-like receptors
    the interaction of the cell wall and plant cells. Integrin-like receptors and integrin-linked kinases together have been implicated in surface adhesion...
    15 KB (1,874 words) - 23:19, 16 May 2025
  • kinase 2 (PDK2), integrin-linked kinase (ILK), mechanistic target of rapamycin complex complex 2 (mTORC2) and DNA-dependent protein kinase (DNA-PK)...
    36 KB (4,072 words) - 15:49, 12 April 2025
  • Thumbnail for PTK2
    Parsons JT (September 1995). "Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains". The Journal of Cell Biology...
    41 KB (4,671 words) - 17:32, 10 June 2025
  • Thumbnail for Major basic protein
    "Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase". Proc. Natl. Acad...
    13 KB (1,519 words) - 06:00, 30 November 2024
  • Thumbnail for NCK2
    "The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells". Molecular and Cellular...
    13 KB (1,551 words) - 21:15, 3 March 2023
  • differentially imprinted GNAI2 HAX1 associated with tyrosine kinases ILK Integrin linked kinase MAPKAPK2 MAP2K2 MAP3K11 PITPNM Phosphatidylinositol transfer...
    48 KB (4,613 words) - 03:06, 27 May 2025
  • Thumbnail for Integrin beta 1
    with integrin alpha 1 and integrin alpha 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha...
    22 KB (2,600 words) - 22:18, 2 April 2024
  • Thumbnail for Costamere
    (MeSH) Srivastava, D.; Yu, S (2006). "Stretching to meet needs: integrin-linked kinase and the cardiac pump". Genes Dev. 20 (17): 2327–2331. doi:10.1101/gad...
    10 KB (1,128 words) - 16:22, 23 October 2023
  • Thumbnail for Cyclin D
    biogenesis. Rho family GTPases, integrin linked kinase and focal adhesion kinase (FAK) activate cyclin D gene in response to integrin. p27Kip1 and p21cip1 are...
    39 KB (4,605 words) - 19:08, 12 April 2025
  • Thumbnail for PAK1
    endothelial-cadherin-S665, poly(RC) binding protein 1-T60-S246, integrin-linked kinase 1-T173-S246, epithelium-specific Ets transcription factor 1-S207...
    43 KB (5,202 words) - 18:21, 2 October 2024
  • mechanisms governing the termination of liver regeneration, involving integrin-linked kinase (ILK) and pericellular proteins like Glypican 3 (GPC3), are highly...
    25 KB (2,734 words) - 13:16, 28 June 2024
  • Thumbnail for Arrhythmogenic cardiomyopathy
    Arrhythmogenic cardiomyopathy (category Commons category link is on Wikidata)
    Liedtke D, Oh T, et al. (June 2019). "Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy". Translational...
    50 KB (5,442 words) - 13:30, 9 June 2025
  • Thumbnail for LIM domain
    erythrocyte antigens. It can bind to ankyrin repeat domains of integrin-linked kinase. Also, LIM domain 4 of PINCH can bind to Nck2 protein to act as...
    17 KB (1,963 words) - 00:38, 16 May 2025
  • Thumbnail for Integrin beta 2
    In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one...
    11 KB (1,299 words) - 10:15, 11 December 2023
  • Myc. This process is described in more detail below. Receptor-linked tyrosine kinases, such as the epidermal growth factor receptor (EGFR), are activated...
    24 KB (3,066 words) - 14:18, 3 June 2025
  • Thumbnail for AKT2
    AKT2 (category Protein kinases)
    "Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase". Proceedings of the...
    13 KB (1,538 words) - 09:28, 24 April 2025