with integrin alpha 1 and integrin alpha 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha 3 to...
22 KB (2,600 words) - 22:18, 2 April 2024
Integrin alpha-1 also CD49a is an integrin alpha subunit encoded in humans by the gene ITGA1. It makes up half of the α1β1 integrin duplex. Though CD49a...
10 KB (1,237 words) - 06:01, 25 September 2024
CD49b gene. The CD49b protein is an integrin alpha subunit. It makes up half of the α2β1 integrin duplex. Integrins are heterodimeric integral membrane...
6 KB (688 words) - 10:07, 22 March 2025
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are...
6 KB (722 words) - 15:22, 16 October 2024
Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins...
4 KB (444 words) - 18:22, 24 April 2024
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes...
5 KB (662 words) - 05:18, 30 January 2023
Integrin alpha-6 is a protein that in humans is encoded by the ITGA6 gene. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are...
4 KB (404 words) - 09:15, 12 September 2024
known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c . CD11c is an integrin alpha X chain protein...
8 KB (992 words) - 02:06, 25 November 2024
is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family...
10 KB (1,210 words) - 20:44, 2 June 2024
Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane...
8 KB (767 words) - 09:34, 21 September 2024
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans...
10 KB (1,239 words) - 08:31, 10 June 2024
Integrins are transmembrane receptors that help cell–cell and cell–extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal...
36 KB (3,928 words) - 22:54, 6 February 2025
Alpha-7 integrin is a protein that in humans is encoded by the ITGA7 gene. Alpha-7 integrin is critical for modulating cell-matrix interactions. Alpha-7...
26 KB (3,169 words) - 03:34, 10 March 2024
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)...
15 KB (1,716 words) - 17:02, 7 November 2023
CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one of a number of alpha chains...
11 KB (1,299 words) - 10:15, 11 December 2023
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed...
4 KB (475 words) - 00:04, 28 November 2023
Integrin alpha-10 also known as ITGA10 is a protein that in humans is encoded by the ITGA10 gene. Integrins are integral membrane proteins composed of...
6 KB (689 words) - 22:14, 7 November 2023
Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene. Cytogenetic location: 3p22.2 This gene encodes an alpha integrin. Integrins...
7 KB (934 words) - 22:12, 3 March 2023
Integrin alpha-11 is a protein that, in humans, is encoded by the ITGA11 gene. This gene encodes an alpha integrin. Integrins are heterodimeric integral...
9 KB (800 words) - 18:20, 15 March 2024
VLA-4 (redirect from Integrin alpha4beta1)
Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the...
9 KB (1,032 words) - 14:42, 18 March 2024
Integrin alpha-D is a protein that in humans is encoded by the ITGAD gene. GRCh38: Ensembl release 89: ENSG00000156886 – Ensembl, May 2017 GRCm38: Ensembl...
4 KB (459 words) - 10:34, 11 January 2024
Integrin α4β7 (Lymphocyte Peyer’s patch adhesion molecule-1) is an integrin heterodimer composed of CD49d (alpha-4) subunit and beta-7 subunit noncovalently...
9 KB (1,246 words) - 08:17, 30 April 2025
Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key role in emigration, which...
8 KB (946 words) - 18:38, 10 March 2023
In cell biology, CD11 is the α (alpha) component of various integrins, especially ones in which the β (beta) component is CD18 (β2) and mediate leukocyte...
1,012 bytes (87 words) - 01:41, 12 July 2023
Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene. GRCh38: Ensembl release 89: ENSG00000077943 – Ensembl, May 2017 GRCm38: Ensembl...
5 KB (625 words) - 03:01, 4 January 2024
receptor, the fibrinogen alpha chain, the integrin alpha chain, Hemoglobin, alpha 1 It should be distinguished from the term alpha helix, which refers to...
1 KB (132 words) - 18:11, 5 September 2022
Alpha 5 (Power Rangers), a fictional character from the Power Rangers franchise Integrin alpha-5, a protein encoded by the ITGA5 gen in humans Alpha-5...
1 KB (238 words) - 06:02, 4 August 2024
Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin...
11 KB (1,414 words) - 06:32, 25 December 2023
Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins...
41 KB (4,724 words) - 23:37, 14 January 2025
Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2)...
9 KB (1,147 words) - 01:46, 25 November 2024