Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene. GRCh38: Ensembl release 89: ENSG00000077943 – Ensembl, May 2017 GRCm38: Ensembl...
5 KB (625 words) - 03:01, 4 January 2024
known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c . CD11c is an integrin alpha X chain protein...
8 KB (992 words) - 02:06, 25 November 2024
is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family...
10 KB (1,210 words) - 06:07, 2 June 2025
Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins...
4 KB (444 words) - 18:22, 24 April 2024
Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane...
8 KB (767 words) - 09:34, 21 September 2024
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans...
10 KB (1,239 words) - 08:31, 10 June 2024
CD49b gene. The CD49b protein is an integrin alpha subunit. It makes up half of the α2β1 integrin duplex. Integrins are heterodimeric integral membrane...
6 KB (688 words) - 10:07, 22 March 2025
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)...
15 KB (1,716 words) - 17:02, 7 November 2023
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes...
5 KB (662 words) - 05:18, 30 January 2023
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are...
6 KB (722 words) - 03:01, 2 June 2025
Alpha-7 integrin is a protein that in humans is encoded by the ITGA7 gene. Alpha-7 integrin is critical for modulating cell-matrix interactions. Alpha-7...
26 KB (3,169 words) - 03:34, 10 March 2024
Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene. Cytogenetic location: 3p22.2 This gene encodes an alpha integrin. Integrins...
7 KB (934 words) - 22:12, 3 March 2023
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed...
4 KB (475 words) - 00:04, 28 November 2023
CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one of a number of alpha chains...
11 KB (1,299 words) - 10:15, 11 December 2023
Integrin alpha-10 also known as ITGA10 is a protein that in humans is encoded by the ITGA10 gene. Integrins are integral membrane proteins composed of...
6 KB (689 words) - 03:06, 28 May 2025
Integrins are transmembrane receptors that help cell–cell and cell–extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal...
36 KB (3,928 words) - 22:54, 6 February 2025
with integrin alpha 1 and integrin alpha 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha 3 to...
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VLA-4 (redirect from Integrin alpha4beta1)
Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the...
9 KB (1,032 words) - 14:42, 18 March 2024
Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin...
11 KB (1,414 words) - 06:32, 25 December 2023
Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins...
41 KB (4,724 words) - 02:44, 2 June 2025
Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene. This gene is a member of the integrin beta chain family and encodes a single-pass...
7 KB (825 words) - 23:51, 3 March 2023
Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. Integrins are heterodimers composed of alpha and beta subunits...
12 KB (1,489 words) - 22:47, 18 October 2022
PMID 7537970. Schnapp LM, Hatch N, Ramos DM, et al. (1995). "The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin"...
20 KB (2,565 words) - 04:57, 23 December 2023
ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given...
9 KB (1,022 words) - 02:24, 9 June 2025
Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene. CD103...
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to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7), blocking the α4β7 integrin results...
26 KB (2,383 words) - 23:12, 25 April 2025
J. F.; Kaminski, N.; Garat, C.; Matthay, M. A.; et al. (1999). "The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating...
20 KB (2,419 words) - 06:46, 9 June 2025
Cell adhesion molecule (section Integrins)
transcription. Integrins are heterodimeric, as they consist of an alpha and beta subunit. There are currently 18 alpha subunits and 8 beta subunits, which...
16 KB (1,889 words) - 11:50, 12 June 2025
migration. Alpha-7 integrin pericytes (AIPs) express several types of integrin chains which generate heterodimers. Integrin chains allow integrin pericytes...
16 KB (1,792 words) - 09:42, 17 March 2023
ectodomain, within amino acids 506-519, is responsible for binding to alpha 6 integrin, this binding seems to be important for the collagen XVII integration...
26 KB (3,010 words) - 04:54, 2 June 2025