The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
24 KB (2,617 words) - 19:43, 7 August 2022
pseudogenes. Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR)...
25 KB (3,061 words) - 00:27, 18 July 2025
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
32 KB (2,859 words) - 06:09, 19 July 2025
interferon-alpha/beta receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28...
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to Interferon-alpha/beta receptor of nearby cells to protect cells from local infection. STING elicits powerful type I interferon immunity against viral...
24 KB (2,749 words) - 08:44, 4 June 2025
JA, Smith GL (December 2000). "The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral...
63 KB (7,124 words) - 04:51, 12 July 2025
Immunodeficiency (X-SCID). Type II cytokine receptors, whose members are receptors mainly for interferons. Immunoglobulin (Ig) superfamily, which are...
6 KB (442 words) - 01:30, 18 July 2025
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene. The protein encoded by this gene is a type I membrane...
11 KB (1,344 words) - 04:17, 15 July 2025
Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene. The protein encoded by this gene is a type I membrane...
11 KB (1,400 words) - 21:49, 15 July 2025
viruses. However, they still have the Interferon-alpha/beta receptor, so they respond normally when recombinant interferon is added to their culture media....
7 KB (837 words) - 22:31, 29 May 2025
The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
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IFNAR1: encoding interferon alpha/beta receptor 1 IFNAR2: encoding interferon alpha/beta receptor 2 IFNGR2: encoding interferon gamma receptor 2 IL10RB: encoding...
33 KB (3,068 words) - 18:55, 17 July 2025
interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature...
26 KB (3,273 words) - 06:10, 19 July 2025
process of seeded nucleation, alpha-synuclein adopts a cross-beta sheet structure characteristic of amyloid fibrils. The human alpha-synuclein protein consists...
84 KB (9,504 words) - 20:48, 23 July 2025
heterodimeric receptor consisting of Interferon gamma receptor 1 (IFNGR1) and Interferon gamma receptor 2 (IFNGR2). IFN-γ binding to the receptor activates...
56 KB (6,491 words) - 17:37, 16 July 2025
region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor". Proceedings of the National Academy...
25 KB (2,850 words) - 04:54, 15 July 2025
Estrogen-related receptor beta (ERR-β), also known as ESRRB or NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a nuclear receptor that in humans...
7 KB (800 words) - 17:15, 16 July 2025
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear...
58 KB (6,134 words) - 16:30, 17 July 2025
1992). "The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci". Genomics. 13 (3):...
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many cell types, the receptors may form ERα (αα) or ERβ (ββ) homodimers or ERαβ (αβ) heterodimers. Estrogen receptor alpha and beta show significant overall...
38 KB (4,152 words) - 07:29, 17 July 2025
Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear...
39 KB (4,526 words) - 16:30, 17 July 2025
Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA gene. Belonging to the...
24 KB (2,773 words) - 21:57, 15 July 2025
glucocorticoid treatment in asthma. The role of alpha and beta isoforms of the glucocorticoid receptor]". Archivos de Bronconeumologia. 38 (9): 436–440...
37 KB (4,047 words) - 22:45, 4 June 2025
factor beta receptor I (activin A receptor type II-like kinase, 53kDa) is a membrane-bound TGF beta receptor protein of the TGF-beta receptor family for...
14 KB (1,608 words) - 18:46, 16 July 2025
hormone receptor is a receptor molecule that binds to a specific hormone. Hormone receptors are a wide family of proteins made up of receptors for thyroid...
17 KB (2,015 words) - 03:11, 30 January 2025
Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon...
25 KB (2,751 words) - 21:50, 15 July 2025
of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systems". Endocrinology...
88 KB (9,476 words) - 15:38, 17 July 2025
Peginterferon alfa-2a (redirect from Pegylated interferon-alpha-2a)
Pegylated interferon alfa-2a is in the alpha interferon family of medications. It is pegylated to protect the molecule from breakdown. Pegylated interferon alfa-2a...
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single transmembrane alpha helix. The insulin receptor is an example. Type 4: Nuclear receptors – While they are called nuclear receptors, they are actually...
26 KB (2,673 words) - 05:54, 5 May 2025