Intermediate filaments (IFs) are cytoskeletal structural components found in the cells of vertebrates, and many invertebrates. Homologues of the IF protein...
30 KB (3,194 words) - 16:59, 6 April 2025
nonfluent (nfvPPA). Two rare distinct subtypes of FTD are neuronal intermediate filament inclusion disease (NIFID) and basophilic inclusion body disease...
56 KB (6,041 words) - 15:37, 17 June 2025
filaments that make up the cytoskeleton include: actin filaments, microtubules and intermediate filaments. Compared to the other parts of the cytoskeletons...
14 KB (1,806 words) - 22:50, 17 August 2024
Keratin (section Filament formation)
organic solvents. Keratin monomers assemble into bundles to form intermediate filaments, which are tough and form strong unmineralized epidermal appendages...
38 KB (3,003 words) - 01:29, 9 June 2025
Solar prominence (redirect from Solar filament)
In solar physics, a prominence, sometimes referred to as a filament, is a large plasma and magnetic field structure extending outward from the Sun's surface...
17 KB (1,902 words) - 05:29, 4 June 2025
Cytoskeleton (section Intermediate filaments)
organisms. It is composed of three main components: microfilaments, intermediate filaments, and microtubules, and these are all capable of rapid growth and...
45 KB (5,117 words) - 13:25, 26 May 2025
Desmosome (redirect from Desmosome-intermediate filament complex)
composed of desmosome-intermediate filament complexes (DIFCs), a network of cadherin proteins, linker proteins and intermediate filaments. The DIFCs can be...
10 KB (1,221 words) - 14:10, 30 August 2024
Peripherin is a type III intermediate filament protein expressed mainly in neurons of the peripheral nervous system. It is also found in neurons of the...
21 KB (2,751 words) - 20:50, 22 May 2025
Neurofilaments (NF) are classed as type IV intermediate filaments found in the cytoplasm of neurons. They are protein polymers measuring 10 nm in diameter...
25 KB (2,595 words) - 18:14, 27 May 2025
which refers to an array of flexible rods. Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins...
23 KB (2,523 words) - 16:49, 14 May 2025
protein that is encoded by the GFAP gene in humans. It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central...
28 KB (3,301 words) - 23:56, 10 August 2024
distributed filaments within the cytoplasm. However, a more substantial number of keratin types participate in the intermediate filament cytoskeletal...
15 KB (1,833 words) - 22:37, 23 May 2025
Internexin, alpha-internexin, is a Class IV intermediate filament approximately 66 kDa. The protein was originally purified from rat optic nerve and spinal...
8 KB (974 words) - 18:24, 26 March 2025
Keratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin...
10 KB (1,175 words) - 02:30, 23 October 2024
encoded by the DES gene. Desmin is a muscle-specific, type III intermediate filament that integrates the sarcolemma, Z disk, and nuclear membrane in...
25 KB (2,717 words) - 14:35, 28 March 2025
anchors intermediate filaments to desmosomal plaques. In cardiomyocytes, desmoplakin forms desmosomal plaques with the intermediate filament desmin, whereas...
28 KB (3,242 words) - 15:17, 21 December 2023
neuroepithelial stem cell protein) is a type VI intermediate filament (IF) protein. These intermediate filament proteins are expressed mostly in nerve cells...
16 KB (1,925 words) - 07:43, 7 April 2025
the NEFL gene. Neurofilament light polypeptide is a member of the intermediate filament protein family. This protein family consists of over 50 human proteins...
23 KB (2,485 words) - 07:08, 11 May 2025
It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed...
9 KB (1,143 words) - 13:43, 25 May 2025
sometimes described as electron dense. The intermediate filaments are connected to other intermediate filaments via dense bodies, which eventually are attached...
37 KB (4,737 words) - 17:18, 22 January 2025
Microfilament (redirect from Actin filament)
Microfilaments, also called actin filaments, are protein filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton. They are primarily...
21 KB (2,801 words) - 14:09, 31 December 2024
of glial fibrillary acidic protein (GFAP). GFAP is an important intermediate filament protein that allows the astrocytes to begin synthesizing more cytoskeletal...
24 KB (2,962 words) - 15:40, 7 June 2024
humans by the KRT5 gene. It dimerizes with keratin 14 and forms the intermediate filaments (IF) that make up the cytoskeleton of basal epithelial cells. This...
22 KB (2,682 words) - 03:34, 2 June 2025
keratin filament precursors are transported by actin fibers in the cell towards the nucleus. There, the alpha-keratin intermediate filaments will collect...
11 KB (1,447 words) - 10:49, 7 March 2025
Myofilament (redirect from Thin filament)
Myofilaments are the three protein filaments of myofibrils in muscle cells. The main proteins involved are myosin, actin, and titin. Myosin and actin...
13 KB (1,711 words) - 04:44, 25 March 2025
superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along...
9 KB (1,104 words) - 02:30, 23 October 2024
stratum corneum, distinguishing them from alpha-keratins, which are intermediate-filament proteins rich in alpha helices. Recent studies suggest that the...
8 KB (858 words) - 03:03, 17 March 2025
Keratin-19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial...
14 KB (1,646 words) - 09:30, 2 November 2024
cytoskeleton of epithelial tissue. They are an important component of intermediate filaments, which help cells resist mechanical stress. Expression of these...
11 KB (988 words) - 03:46, 7 May 2025
Crescentin (section Assembly of filaments)
Crescentin is a protein which is a bacterial relative of the intermediate filaments found in eukaryotic cells. Just as tubulins and actins, the other major...
8 KB (1,004 words) - 12:10, 22 May 2025