Left-right determination factor 2 (Lefty2) aka TGFB4 is a protein that is encoded by the LEFTY2 gene in humans. Lefty2 is a protein from the TGF-beta cytokine...
2 KB (294 words) - 14:16, 4 April 2025
embryos. In chick embryos the left side expresses genes called NODAL and LEFTY2 that activate PITX2 to signal the development of left side structures. Whereas...
35 KB (4,100 words) - 22:22, 30 December 2024
GDF9; GDF10; GDF11; GDF15; GDNF; INHA; INHBA; INHBB; INHBC; INHBE; LEFTY1; LEFTY2; MSTN; NODAL; NRTN; PSPN; TGFB1; TGFB2; TGFB3; Schlunegger MP, Grütter MG...
7 KB (595 words) - 19:43, 1 January 2025
HGNC:6550 O14960 8643 LEF1 HGNC:6551 Q9UJU2 8644 LEFTY1 HGNC:6552 O75610 8645 LEFTY2 HGNC:3122 O00292 8646 LEKR1 HGNC:33765 Q6ZMV7 8647 LELP1 HGNC:32046 Q5T871...
277 KB (17 words) - 18:41, 6 October 2024
miR-302. In zebra fish the miR-430 inhibits translation of Sqt, Lefty1 and Lefty2, in frogs miR-427 regulate Xnr5, Xnr6b, LeftyA and LeftyB, however in humans...
27 KB (3,398 words) - 18:33, 6 July 2024
inferior vena cava, and lack of lung asymmetry (left pulmonary isomerism). Lefty2 may play a role in endometrial bleeding. Lefty-1 is a regulatory gene that...
11 KB (1,327 words) - 04:35, 13 August 2023
activates a further signalling cascade of genes including Nodal, Pitx2 and Lefty2. In chickens, LR asymmetry is established at a structure called Hensen’s...
16 KB (2,000 words) - 12:49, 30 January 2025