Large dense core vesicle (LDCVs) are lipid vesicles in neurons and secretory cells which may be filled with neurotransmitters, such as catecholamines...

synthesized from large precursor proteins which are cleaved and post-translationally processed then packaged into large dense core vesicles. Neuropeptides...

on the target cell. Some neurotransmitters are also stored in large dense core vesicles. The neurotransmitter's effect on the target cell is determined...

large (80–120 nm diameter) dense-core vesicles that are considerably larger than vesicles storing neurotransmitters. These large dense-core vesicles differ...

shell than in the core. They are also larger and thicker, and contain more large dense core vesicles than their counterparts in the core. The nucleus accumbens...

evidence that PI(4,5)P2 plays a pivotal role during the LDCV (Large dense core vesicle) exocytosis process.[citation needed] Through the use of PI-specific...

synaptic vesicles. Two kinds of neurotransmitter vesicles exist: large dense core vesicles and small clear core vesicles. Large dense core vesicles contain...

osmotically sensitive, contain numerous small clear synaptic vesicles, sometimes larger dense-core vesicles and frequently one or more small mitochondria. They...

in chromaffin cells to investigate catecholamine release from large dense core vesicles. Any analyte that can be oxidized or reduced is a candidate for...

expressed in humans: VMAT1 and VMAT2. VMAT1 is expressed mainly in large dense-core vesicles (LDCVs) of the peripheral nervous system. VMAT1 may be found in...

is packaged in large, dense-core vesicles, where it is bound to neurophysin I as shown in the inset of the figure; neurophysin is a large peptide fragment...

transported from the cytosol into secretory vesicles, including synaptic vesicles, small and large dense core vesicles by a solute carrier—a vesicular monoamine...

synaptic vesicles. Two types of vesicles are small synaptic vessicles (SSVs), which are about 40-60nm in diameter, and large dense-core vesicles (LDCVs)...

In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse. The release is regulated...

multiple peptide hormones. Each of these peptides is packaged in large dense-core vesicles that are released from the cells by exocytosis in response to...

neuroendocrine cells, synaptic-like vesicles (SLVs) undergo kiss-and-run, but it's been controversial whether large dense-core vesicles (LDCVs) also undergo kiss-and-run...

of pumice and ash deposits (including deep sea core samples), researchers have been able to make dense-rock equivalent volume estimates for each of the...

organelles called unique organelles including dense granules. Dense granules, along with other secretory vesicles such as a microneme and rhoptry secrete proteins...

these cells are 1) large bundles of microfilaments and 2) vesicles with electron-dense cores in the cytoplasm. These dense-core vesicles have been shown...

action of synaptic vesicles which are, inside the cell, loaded with the neurotransmitters to be released later. These loaded vesicles fuse with the cell...

mediate the fusion of vesicles with the target membrane; this notably mediates exocytosis, but can also mediate the fusion of vesicles with membrane-bound...

of an electron-dense structure, the synaptic ribbon, that holds vesicles close to the active zone. It is characterized by a tight vesicle-calcium channel...

managed by dopamine. VMAT1 is found in both large dense-core vesicles (LDCVs) as well as in small synaptic vesicles (SSVs). This was discovered via studying...

postsynaptic density. They also have a relatively high concentration of dense-core vesicles, which are thought to deliver structural proteins to the presynaptic...

calyx of Held and endbulb of Held hold vesicles containing glutamate on the presynaptic terminal; the vesicles are released upon stimulation (originating...

microvilli. Each microvillus has a dense bundle of cross-linked actin filaments, which serves as its structural core. 20 to 30 tightly bundled actin filaments...

components of the nucleolus are recognized: the fibrillar center (FC), the dense fibrillar component (DFC), and the granular component (GC). Transcription...

porous membranes to form RBC membrane-derived vesicles. The vesicles are fused with nanoparticle cores through methods like co-extrusion, where the mixture...

long-distance transport of membranous cargo, such as synaptic vesicle precursors (SVPs) and dense core vesicles (DCVs), that are essential for the maintenance and...

calcium-binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. This gene interacts with brain-derived...