In toxicology, the lowest published toxic dose (Toxic Dose Low, TDLo) is the lowest dosage per unit of bodyweight (typically stated in milligrams per kilogram)...

In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation. Because resistance varies from...

lethal dose, 50 percent kill; LDLo means lowest published lethal dose; TDLo means lowest published toxic dose For humans the lowest published oral lethal...

lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given...

sensitization. The sulfonyl nitrate part of the compound causes ocular toxicity. "Glysobuzole". pubchem.ncbi.nlm.nih.gov. Smith, Michael, October 17- (2016)...

doses, latrunculin can induce acute cell injury and programmed cell death through activating the caspase-3/7 pathway. TDLO - Lowest Published Toxic Dose...

developmental toxicity from embryonic stage to birth are called teratogens. The effect of the developmental toxicants depends on the type of substance, dose, duration...

to ensure that the lowest effective dose is administered (a lower dose would not fully treat the envenomation, and a higher dose may be particularly...

does so in multiple conformations. In high doses, strychnine is very toxic to humans (minimum lethal oral dose in adults is 30–120 mg) and many other animals...

single species exposure. A dose–response relationship is most commonly used with a sigmoidal curve to quantify the toxic effects at a selected end-point...

Many of the TG for health effects (toxicity tests) function together, in a process called ‘dose-ranging’; lowering doses while extending exposure period...

was observed, even at the lowest dose. The data presented in this study suggest that BTC possess a low order of oral toxicity in the rat. Genotoxic potential...

possible dose of amiodarone leads to a lower incidence of pulmonary toxicity. b) Regular monitoring, in order to diagnose any possible pulmonary toxicity early...

revealed toxic effects in the lungs, stomach and intestines of rats. Based on this animal data, DMP does not fit the definition of ''acute toxic'' under...

Phosgene is an organic chemical compound with the formula COCl2. It is a toxic, colorless gas; in low concentrations, its musty odor resembles that of...

preparation has since been outlawed. Despite its potential toxicity to mammals in large enough doses, picrotoxin is also sometimes used as a performance enhancer...

a slight onion-like odour. Like all strong alkylating agents, Me2SO4 is toxic. Its use as a laboratory reagent has been superseded to some extent by methyl...

removing it from use. In the 1960s, the first clinical works were published proving the toxicity of this compound in humans, e.g. by Mirosław Jan Stasik. In...

tissue on contact. Paraquat is highly toxic to humans and other animals. The toxicity and lethality depends on the dose and how the herbicide is absorbed...

of departure is viewed (i.e., NOEL or "lowest-observed-adverse-effect level", LOAEL), or whether a benchmark dose should be used to derive the RfD. Defining...

kidneys. Fatal dose of barium chloride for a human has been reported to be about 0.8-0.9 g. Systemic effects of acute barium chloride toxicity include abdominal...

were found in the gills and cap with the lowest levels in the spores and mycelium. An additional study published in 2013 by many of the same authors found...

Lethal dose or concentration (LD, LC): LC50 (median concentration) 77 ppm (rat, 4 hr) 152 ppm (mouse, 2 hr) 500 ppm (guinea pig, 1 hr) LCLo (lowest published)...

tests. The recommended maximum daily dose for an adult is three to four grams. Higher doses may lead to toxicity, including liver failure. Paracetamol...

in propellants (e.g., smokeless gunpowders). As it is carcinogenic and toxic, modern formulations tend to avoid its use. In this application it is often...

carefully select doses until they determine the highest dose that presents an adverse (toxic, but not deadly) effect not observed in lowest dose. When adverse...

(median concentration) 1140 ppm (rat, 2 hr) 1000 ppm (mouse, 2 hr) LCLo (lowest published) 2207 ppm (rabbit, 2.5 hr) 2207 ppm (guinea pig, 80 min) 2207 ppm (cat...

is in packing group 1. Chloroprene is toxic. It is reactive towards air, producing peroxides, which are also toxic. Handling of and exposure to chloroprene...

The toxicity of curare alkaloids in humans has not been systematically established, but it is considered highly toxic and slow-acting, with a lowest reported...

were reported worldwide between 2010 and 2020. Although the lowest published fatal ingested dose is 4.3 mg/kg, a typical overdose death occurs at a higher...