Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. It is a member of T cell factor/lymphoid enhancer factor...
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List of MeSH codes (D12.776.930) (section MeSH D12.776.930.875.500 – lymphoid enhancer-binding factor 1)
CCAAT-enhancer-binding protein-alpha MeSH D12.776.930.127.124.750 – CCAAT-enhancer-binding protein-beta MeSH D12.776.930.127.124.812 – CCAAT-enhancer-binding...
30 KB (1,091 words) - 17:13, 17 July 2025
transcription factors MeSH D12.776.660.235.400.800.500 – lymphoid enhancer-binding factor 1 MeSH D12.776.660.235.400.800.750 – t cell transcription factor 1 MeSH D12...
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High-mobility group (category Transcription factors)
etc. TCF/LEF family (T cell factor/lymphoid enhancer factor family) LEF1 (Lymphoid enhancer-binding factor 1) TCF7 (TCF-1) TCF7L1 (TCF-3) TCF7L2 (TCF-4)...
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List of MeSH codes (D12.776.260) (section MeSH D12.776.260.730.500 – lymphoid enhancer-binding factor 1)
ccaat-enhancer-binding protein-alpha MeSH D12.776.260.108.124.750 – ccaat-enhancer-binding protein-beta MeSH D12.776.260.108.124.812 – ccaat-enhancer-binding...
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of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways"...
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beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity". The Journal of Cell Biology. 148 (1): 173–88. doi:10.1083/jcb.148.1.173. PMC 3207144...
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located in the cell nucleus, lymphoid enhancer-binding factor 1, in ~80% of cases. The RS cells in HL-RT are spread throughout 1) a CLL/SLL-like background...
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complex formation (See figures on the right). Expression of lymphoid enhancer-binding factor 1 (LEF-1) triggers the translocation of β-catenin to the nucleus...
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of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in...
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Experimental Forest, a UNESCO Biosphere Reserve in Puerto Rico Lymphoid enhancer-binding factor 1, a protein in humans Lef Nosi (1877–1946), Albanian publisher...
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iC3b and can be involved in cellular adhesion, binding to the intercellular adhesion molecule-1 (ICAM-1). CR3 causes phagocytosis and destruction of cells...
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growth factor. Stimulates IL-1 synthesis. Activates B-cells and NK cells. IL-3 – Stimulates production of all non-lymphoid cells. IL-4 – Growth factor for...
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Aryl hydrocarbon receptor (category Transcription factors)
AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. Upon ligand binding to chemicals such as 2,3,7...
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Binding Proteins, and Lymphoid enhancer-binding factor 1. ETS1, Ccaat-enhancer-binding proteins, and Lymphoid enhancer-binding factor 1 are all related to...
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in early pre-B acute lymphoid leukaemia. ERG and ETV1 are known gene fusions found in prostate cancer. In addition, ETS factors, e.g. the vertebrate Etv1...
10 KB (1,058 words) - 23:17, 24 May 2025
Outline of immunology (section Primary lymphoid organs)
invariant T cells Innate lymphoid cells (ILC) Group 1 ILC Natural killer cells (NK cells) Group 2 ILC Nuocyte Group 3 ILC Lymphoid Tissue inducer cells (LTi...
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NF-κB (redirect from Nuclear factor-kappa B)
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription...
90 KB (9,842 words) - 21:54, 10 July 2025
RUNX1 (redirect from Runt-related transcription factor 1)
cis-regulatory element (+23 RUNX1 enhancer). This +23 RUNX1 enhancer contains conserved motifs that encourage binding of various haematopoiesis related...
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growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein". The Journal of Cell Biology. 124 (1–2): 171–81...
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transcription factor TCF3 and its negative regulator ID3 are found in about 70% of cases of Burkitt lymphoma. These mutations prevent ID3 from binding to and...
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T helper cell (redirect from Type 1 T-cell)
recent thymic emigrants (RTE)) egress from the thymus and home to secondary lymphoid organs (SLO; spleen and lymph nodes). Of note, only a very small minority...
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formed by lymphoid cell-antigen interaction". Proc. Natl. Acad. Sci. U.S.A. 56 (1): 72–77. Bibcode:1966PNAS...56...72D. doi:10.1073/pnas.56.1.72. PMC 285677...
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Nuclear receptor 4A1 (redirect from Nerve growth factor ib)
enhancing immunity against tumor and chronic virus. Mechanistically, NR4A1 is preferentially recruited to binding sites of the transcription factor AP-1...
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(December 1992). "Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes". The...
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Haematopoiesis (redirect from Haematopoietic growth factor)
from HSC to a multipotent progenitor (MPP) is transcription factor CCAAT-enhancer binding protein α (C/EBPα). Mutations in C/EBPα are associated with...
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TCF3 (category Transcription factors)
Transcription factor 3 (E2A immunoglobulin enhancer-binding factors E12/E47), also known as TCF3, is a protein that in humans is encoded by the TCF3 gene...
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for cell motility. WASp is required for various functions in myeloid and lymphoid immune cells. Many of these, such as phagocytosis and podosome formation...
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Mothers against decapentaplegic homolog 2 (redirect from JV18-1)
of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-β and Wnt pathways"...
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