Membrane-bound transcription factor site-1 protease, or site-1 protease (S1P) for short, also known as subtilisin/kexin-isozyme 1 (SKI-1), is an enzyme...

Membrane-bound transcription factor site-2 protease, also known as S2P endopeptidase or site-2 protease (S2P), is an enzyme (EC 3.4.24.85) encoded by...

to protect the cII protein from proteolysis by FtsH (a membrane-bound essential E. coli protease) by acting as a competitive inhibitor. This inhibition...

c-Fos, c-Jun, ATF and JDP families. AP-1 was first discovered as a TPA-activated transcription factor that bound to a cis-regulatory element of the human...

is tightly bound to nucleocapsid proteins, p7, and enzymes needed for the development of the virion such as reverse transcriptase, proteases, ribonuclease...

serine protease, and cleaves the N-terminal of the beta subunit, thereby activating the protein into functional NGF. The term nerve growth factor usually...

platelet released protein TLT-1 has been shown to induce AICD like cell death in CD8 T cells The transcription factor Eomesodermin is suggested to play...

highly regulated mechanism. Along with ADAMs and MT-MMPs, membrane-bound serine proteases also may play a role in ectodomain shedding. The formation...

or geranylgeranyl-isoprenoid membrane anchor is added to a cysteine residue near the C-terminus. Small, membrane-bound G proteins are often modified...

subunits bound together by -S-S- bonds. In addition to tetrameric forms of α2-macroglobulin, dimeric, and more recently monomeric αM protease inhibitors...

ligand recognition. As a membrane anchored-growth factor, TGF-α can be cleaved from an integral membrane glycoprotein via a protease. Soluble forms of TGF-α...

Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded...

leucine zipper class of transcription factors. Unactivated SREBPs are attached to the nuclear envelope and endoplasmic reticulum membranes. In cells with low...

also been created with a modified protease cleavage site in fusion protein (F). The SeV F protein is a type I membrane glycoprotein that is synthesized...

Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells. They act in cell...

proteins which have a serine protease activity. The TMPRSS2 protein is found in high concentration in the cell membranes of epithelial cells of the lung...

basic structure of the biological membranes enclosing all cells, vesicles, and membrane-bound organelles. membrane protein Any protein that is closely...

regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor". Cell. 89 (3): 331–340. doi:10.1016/S0092-8674(00)80213-5...

cleavage site can boost viral entry in different cell types by enabling promiscuous cleavage of the spike when contacting different proteases. On entry...

bFGF is present in basement membranes and in the subendothelial extracellular matrix of blood vessels. It stays membrane-bound as long as there is no signal...

ligands bind externally to the membrane, the ligands of GPCRs typically bind within the transmembrane domain. However, protease-activated receptors are activated...

Proteinase-activated receptor 1 (PAR1) also known as protease-activated receptor 1, coagulation factor II receptor and thrombin receptor is a protein that...

bud from the plasma membrane. In all retroviruses the Gag protein is the precursor to the internal structural protein. Protease (pro) is expressed differently...

eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate...

Phosphorylation of the cytosolic components of NADPH oxidase, a large membrane-bound, multi-protein enzyme present in phagocytic cells, plays an important...

transcription factor 2 (SREBF2) is a protein that in humans is encoded by the SREBF2 gene. This gene encodes a ubiquitously expressed transcription factor...

Translocation of the activated chromosome fragment from under membrane region to euchromatin where transcription starts. This movement requires the interaction of...

membrane protease, that passes the signal through the membrane to the sigmaE transcription factor. However, some studies suggest that an increase in damaged...

(June 2009). "Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysis". The Journal...

experimentally. The promoter was predicted and analyzed for transcription factor binding sites using the ElDorado software on the Genomatix software suite...