The process of messenger RNA decapping consists of hydrolysis of the 5' cap structure on the RNA exposing a 5' monophosphate. In eukaryotes, this 5' monophosphate...

precursor messenger RNA. This process, known as mRNA capping, is highly regulated and vital in the creation of stable and mature messenger RNA able to undergo...

In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is...

that stabilizes mRNA and prevents its degradation by 5' exonucleases. m7G(5')pppN diphosphatase METTL1 Messenger RNA decapping 23S rRNA (guanine2445-N2)-methyltransferase...

Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine monophosphates;...

group, including mephedrone and khat. 5' cap 7-Methylguanosine Messenger RNA decapping Nuss, Donald L.; Furuichi, Yasuhiro (1977). "Characterization of...

5' mRNA decay. P-bodies were originally proposed to be the sites of mRNA degradation in the cell and involved in decapping and digestion of mRNAs earmarked...

regulating the RNA degradation activity of the complex to substrates specific to these cell compartments. Substrates of the exosome include messenger RNA, ribosomal...

examined promoters for decapping and how the promoters impede the translation and destruction of mRNA. “Decapping and Decay of Messenger RNA Occur in Cytoplasmic...

supports translation, the NAD+ cap targets the RNA transcript for decay, facilitated by the non-canonical decapping enzyme, DXO. Considering the centrality of...

message from decapping. When translationally repressed or marked for decay by various mechanisms the 5' cap is bound by the mRNA decapping enzyme DCP2...

RNA degradation, for instance ribonucleases, helicases, 3'-end nucleotidyltransferases (which add tails to transcripts), 5'-end capping and decapping...

heterodimer (CBP20/CBP80), which aids in mRNA export to cytoplasm and also protect the RNA from decapping. Another modification is 3′ cleavage and polyadenylation...

cytosol composed of proteins and RNA that assemble into 0.1–2 μm membraneless organelles when the cell is under stress. The mRNA molecules found in stress granules...

exonucleases, and promote translation in the cytoplasm. Mature mRNAs can also be decapped. 5' untranslated region (5'-UTR) 5-bromodeoxyuridine See bromodeoxyuridine...

RNA ends (PARE), and degradome sequencing use the T4 ligase of the Illumina sequencing platform to sequence decapped mRNAs. T4 ligase ligates on RNA with...

for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing". RNA. 11 (11): 1640–1647. doi:10.1261/rna.2191905. PMC 1370850. PMID 16177138...

U6 snRNA-associated Sm-like protein LSm1 is a protein that in humans is encoded by the LSM1 gene. Sm-like proteins were identified in a variety of organisms...

Izaurralde, Elisa (15 July 2006). "mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes". Genes & Development...

Mohammad; Taverniti, Valerio; et al. (2015-06-01). "Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular...