Mevalonate kinase deficiency (MKD) is an autosomal recessive metabolic disorder that disrupts the biosynthesis of cholesterol and isoprenoids. It is a...

Mevalonate kinase is an enzyme (specifically a kinase) that in humans is encoded by the MVK gene. Mevalonate kinases are found in a wide variety of organisms...

diseases such as osteoporosis) A number of diseases affect the mevalonate pathway: Mevalonate Kinase Deficiency Mevalonic Aciduria Hyperimmunoglobulinemia D...

classified mevalonate diphosphate decarboxylase as an enzyme in the GHMP kinase family (galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate...

code North Macedonia, ISO 3166-1 alpha-3 code and IOC country code Mevalonate kinase deficiency, a metabolic disorder mkd (software), a documentation extractor...

The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate...

infection. Episodic and multisystem AIDs (NLRP12-associated disease, mevalonate kinase deficiency, PFAPA (periodic fever syndrome, aphthous stomatitis, pharyngitis...

periodic syndrome (TRAPS), hyperimmunoglobulin D syndrome (HIDS)/mevalonate kinase deficiency (MKD), and familial mediterranean fever (FMF). In June...

and in two additional autoinflammatory recurrent fever syndromes: mevalonate kinase deficiency (hyper-immunoglobulin D syndrome, or HIDS) and tumor necrosis...

phytol kinase EC 2.7.1.183: glycoprotein-mannosyl O6-kinase EC 2.7.1.184: sulfofructose kinase EC 2.7.1.185: mevalonate 3-kinase EC 2.7.1.186: mevalonate-3-phosphate...

(HIDS). This is now (along with mevalonic aciduria) defined as a mevalonate kinase deficiency 260920 MVK TNF receptor associated periodic syndrome (TRAPS)...

kinase family is a family of kinase enzymes. Members of this family include homoserine kinases EC 2.7.1.39, galactokinases EC 2.7.1.6, and mevalonate...

(or CDP-ME) is an intermediate in the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis. It is produced by the enzyme...

for Familial Mediterranean fever, Hyper-IgD syndrome also known as Mevalonate kinase deficiency, and TNF receptor associated periodic syndrome (TRAPS)...

competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway. Because statins are similar in structure to HMG-CoA on a molecular...

Phosphomevalonate kinase is an enzyme (EC 2.7.4.2) in the mevalonate pathway that in humans is encoded by the PMVK gene. GRCh38: Ensembl release 89: ENSG00000163344...

its original members: galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase. Members of the GHMP superfamily have great three-dimensional...

"Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step". Proceedings...

within the peroxisomes of the apocrine glands by enzymes such as mevalonate kinases. Pheromones are a factor seen in the mating selection and reproduction...

encompasses both hereditary types (familial Mediterranean fever, mevalonate kinase deficiency, TNF receptor associated periodic syndrome, cryopyrin-associated...

mut-0 Methylmalonyl-Coenzyme A mutase deficiency Methemoglobinemia Mevalonate kinase deficiency Mevalonicaciduria Meyenburg–Altherr–Uehlinger syndrome...

This enzyme is also called CDP-ME kinase, and IspE. This enzyme participates in the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis...

receptor associated periodic syndrome (TRAPS) Hyper-IgD syndrome (Mevalonate kinase deficiency) CIAS1-related diseases: Muckle–Wells syndrome Familial...

is activated on perception, which then converts HMG-CoA into mevalonate. This mevalonate acts as a second messenger and activates a nuclear K+ cation...

Hyperimmunoglobulin D syndrome in 50% of cases is associated with mevalonate kinase deficiency which can be measured in the leukocytes.[citation needed]...

enzyme (NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids...

of the HMG-CoA reductase pathway. The product of HMG CoA reductase is mevalonate. By combining precursors with 5 carbons, the pathway subsequently produces...

(plague) Controls ASC-mediated apoptosis Familial Mediterranean fever (FMF), mevalonate kinase deficiency (MKD), hyperimmunoglobulinemia D syndrome (HIDS)...

The resulting mevalonate is then sequentially phosphorylated by two separate kinases, mevalonate kinase and phosphomevalonate kinase, to form 5-pyrophosphomevalonate...

(or mevalonate-5-pyrophosphate, or 5-pyrophosphomevalonate) is an intermediate in the mevalonate pathway. Mevalonic acid Phosphomevalonate kinase Pyrophosphomevalonate...