Mitochondrial ROS (mtROS or mROS) are reactive oxygen species (ROS) that are produced by mitochondria. Generation of mitochondrial ROS mainly takes place...

Complex III. Another source of ROS production in animal cells is the electron transfer reactions catalyzed by the mitochondrial P450 systems in steroidogenic...

the 1950s, and in the 1970s extended the idea to implicate mitochondrial production of ROS. In some model organisms, such as yeast and Drosophila, there...

Wojtowicz EE, Smith JG, et al. (December 2019). "ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem...

levels are associated with ageing, as mitochondrial stress will remain and increase ROS levels. Such mitochondrial stress and dysfunction has been linked...

biochemical properties of the mitochondrial DNA and the longevity of species. The application of a mitochondrial-specific ROS scavenger, which lead to a...

"Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS". Nature. 515 (7527): 431–435. Bibcode:2014Natur.515..431C. doi:10...

interconverts succinate into fumarate participates in mitochondrial reactive oxygen species (ROS) production by directing electron flow in the electron...

separate dangerously infected individuals from healthy ones. Mitochondrial ROS – The production of ROS by the mitochondria. This causes oxidative damage to the...

Implicated pathways include NF-κB, PI3K, HIFs and MAPKs. In humans, mitochondrial ROS is required alongside those released in the oxidative burst for mitogenic...

Reverse electron transfer supports the highest rate of mitochondrial Reactive Oxygen Species (ROS) production, and complex I flavin mononucleotide (FMN)...

MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like episodes) is one of the family of mitochondrial diseases, which also include MIDD...

NADPH oxidase–independent form of NETosis, relying solely on mitochondrial-derived ROS, has also been described. Azurophilic granule proteins such as...

cytochrome c.[citation needed] During the early phase of apoptosis, mitochondrial ROS production is stimulated, and cardiolipin is oxidized by a peroxidase...

of de novo nucleotide synthesis resulting from AMPK activation and mitochondrial ROS-mediated apoptosis. Meanwhile, Oike et al. demonstrated the generalizability...

The mitochondrial permeability transition pore (mPTP or MPTP; also referred to as PTP, mTP or MTP) is a protein that is formed in the inner membrane of...

– S58. PMID 11191275. Cobley JN (September 2020). "Mechanisms of Mitochondrial ROS Production in Assisted Reproduction: The Known, the Unknown, and the...

receptors. Along with PPIF, PPID regulates mitochondrial apoptosis. In response to elevated reactive oxygen species (ROS) and calcium ion levels, PPID interacts...

C, Giordano S, Chiarugi P (August 2011). "HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in...

response to oxidative stress characterized by elevated ROS and altered cellular metabolism Mitochondrial dysfunction Defects in neuronal function: Inappropriate...

Calorini L, Torre E, et al. (August 2011). "HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in...

prevent cardiac dysfunction after ischemia-reperfusion injuries. Mitochondrial ROS production and oxidative mtDNA damage is increased during reoxygenation...

ROS and to protect patient-derived cells from redox perturbation were tested on mitochondrial patient cells. The calculated IC50 values from the ROS assay...

also reduces ROS by increasing the activity of HK2. HK2 reduces ROS levels indirectly by keeping ADP levels at the outer mitochondrial membrane high...

4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS". AJP: Heart and Circulatory Physiology. 290 (1): H450 – H457. doi:10...

marrow, and low levels of mitochondrial respiration protect quiescent cells from damage induced ROS. When excessive levels of ROS are present, LT-HSCs undergo...

from the mitochondrial matrix into the intermembrane space, creating an electrochemical proton gradient (ΔpH) across the inner mitochondrial membrane...

chaperones and proteases to re-establish mitochondrial proteostasis, increase ROS detoxification, and increase mitochondrial import machinery. Recent research...

the damaging effects of reactive oxygen species (ROS). ROS are a natural bi-product of the mitochondrial production of ATP. As such, if they are allowed...

inducing mitochondrial membrane damage, but does not disrupt host mitochondrial membrane potential, as well as reactive oxygen species (ROS) generation...