Monoclonal immunoglobulin deposition disease, or MIDD, is a disease characterised by the deposition of monoclonal immunoglobulins on the basement membrane...
16 KB (1,734 words) - 20:00, 20 December 2023
chain deposition disease (LCDD) is a rare blood cell disease which is characterized by deposition of fragments of infection-fighting immunoglobulins, called...
31 KB (3,057 words) - 23:01, 12 January 2024
cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones...
81 KB (10,827 words) - 12:54, 14 March 2024
deposits in the mesangium and glomerular basement membrane. Monoclonal immunoglobulin deposition disease (MIDD) involves light chains with unusual characteristics...
14 KB (1,590 words) - 21:26, 19 February 2024
Multiple myeloma (redirect from Kahler's disease)
aggregate, the immunoglobulin level may be elevated with the disease, but the majority of such increased antibodies are of a monoclonal variety due to...
131 KB (13,418 words) - 07:38, 9 June 2024
physician astute in new and evolving connective tissue diseases such as IgG4-RD. Serum immunoglobulin G4 (IGG4) is often elevated, but this is not always...
59 KB (4,911 words) - 23:15, 8 May 2024
Cryoglobulinemia (category Hepatitis C virus-associated diseases)
cryoglobulinemic disease, characterized on the monoclonal immunoglobulin(s) comprising the involved cryoglobulin, percentage of total cryoglobulinemic disease cases...
28 KB (2,996 words) - 22:29, 24 January 2024
(also known as multiple myeloma) Plasmacytoma Monoclonal immunoglobulin deposition diseases Heavy chain diseases Extranodal marginal zone B cell lymphoma,...
68 KB (6,701 words) - 20:31, 23 April 2024
plasmacytoma Monoclonal immunoglobulin deposition diseases Primary amyloidosis Light chain and heavy chain deposition diseases Extranodal marginal zone...
24 KB (2,330 words) - 08:56, 9 June 2024
Chronic inflammatory demyelinating polyneuropathy (category Autoimmune diseases)
oligoclonal IgG bands in the cerebrospinal fluid and immunoglobulin as well as complement deposition on myelinated nerve fibers. Target antigens may also...
44 KB (4,880 words) - 13:02, 20 May 2024
Proteinopathy (redirect from Protein misfolding disease)
include such diseases as Creutzfeldt–Jakob disease (and a variant associated with mad cow disease) and other prion diseases, Alzheimer's disease, Parkinson's...
62 KB (4,594 words) - 07:50, 3 June 2024
Scleroderma (category Autoimmune diseases)
a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. The disease can be either localized...
38 KB (3,291 words) - 01:18, 9 May 2024
Yokoo, Takashi; Shimizu, Akira (2019-01-15). "Monoclonal Immunoglobulin Deposition Disease and Related Diseases". Journal of Nippon Medical School. 86 (1):...
10 KB (1,075 words) - 19:04, 16 April 2024
Cardiac amyloidosis (category Heart diseases)
presence of monoclonal immunoglobulin is also done through immunofixation for detection of the monoclonal band. Presence of the monoclonal band would be...
30 KB (3,368 words) - 04:03, 12 February 2024
cyclophosphamide, low dose IL-2, intravenous immunoglobulins, and belimumab. Omalizumab is a monoclonal antibody that interacts with the binding site...
20 KB (1,820 words) - 13:08, 14 March 2024
Lupus (redirect from Lupus disease)
"Intravenous Immunoglobulins (IVIGs) in Lupus Central Station, sourced from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National...
119 KB (13,043 words) - 20:09, 26 May 2024
tests can be used to diagnose and monitor diseases like multiple myeloma and amyloidosis. Each immunoglobulin light-chain molecule contains approximately...
26 KB (3,338 words) - 06:08, 10 February 2024
AA amyloidosis (category Rare diseases)
AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of...
17 KB (1,566 words) - 01:55, 23 May 2024
[citation needed] Primary amyloidosis (AL) is caused by the deposition of excess immunoglobulin light chains which are secreted from plasma cells.[citation...
24 KB (2,793 words) - 18:41, 30 May 2024
List of skin conditions (redirect from Sweat gland disease)
monoclonal gammopathy–skin changes syndrome (Crow–Fukase syndrome) Polyostotic fibrous dysplasia (Albright's disease) Popliteal pterygium...
198 KB (17,977 words) - 12:52, 16 May 2024
Lupus vasculitis (category Vascular diseases)
with high-dose intravenous corticosteroids, monoclonal antibodies, cyclophosphamide, intravenous immunoglobulin (IVIG), or plasmapheresis. For skin involvement...
31 KB (3,027 words) - 20:31, 26 May 2024
Antibody-dependent enhancement (redirect from Disease enhancement)
reported. Infection induces the production of neutralizing homotypic immunoglobulin G (IgG) antibodies that provide lifelong immunity against the infecting...
42 KB (4,832 words) - 05:54, 27 May 2024
affecting the blood vessels caused by the deposition of abnormal proteins called cryoglobulins. These immunoglobulin proteins are soluble at normal body temperatures...
11 KB (1,262 words) - 00:55, 5 October 2023
reaction with antibodies. All variants of immunoelectrophoresis require immunoglobulins, also known as antibodies, reacting with the proteins to be separated...
15 KB (1,737 words) - 17:08, 4 May 2024
invasion of these tissues by plasma cells and/or the deposition of their circulating monoclonal immunoglobulin in them. Compared to multiple myeloma patients...
18 KB (2,169 words) - 18:25, 29 April 2024
Colony stimulating factor 1 receptor (category Immunoglobulin superfamily cytokine receptors)
affects bone deposition (osteoblasts). In inflammatory arthritis conditions such as rheumatoid arthritis, psoriatic arthritis, and Crohn's disease, proinflammatory...
44 KB (4,593 words) - 17:52, 18 April 2024
M9768/1 T-gamma lymphoproliferative disease M9769/1 Immunoglobulin deposition disease Systemic light chain disease Primary amyloidosis M9800/3 Leukemia...
138 KB (9,870 words) - 22:47, 9 June 2024
Osteopontin (section Parkinson's disease)
(December 1996). "Protective effects of monoclonal antibody to VLA-4 on leukocyte adhesion and course of disease in adjuvant arthritis in rats". The Journal...
72 KB (8,315 words) - 20:27, 19 February 2024
collagen deposition. The deposition then influences the airway remodelling in asthmatic patients. Besides its well-established role in respiratory diseases IL-13...
24 KB (3,043 words) - 02:36, 1 June 2024
Research in multiple sclerosis (category Autoimmune diseases)
when taking natalizumab. While monoclonal antibodies are probably going to have some role in the treatment of the disease in the future, it is believed...
68 KB (7,886 words) - 08:01, 6 May 2024