Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a genetic disorder caused by R179 missense mutations in the ACTA2 gene. Initially described...

origin, although coronary artery smooth muscle is of mesodermal origin. Multisystemic smooth muscle dysfunction syndrome is a genetic condition in which...

stroke, Moyamoya disease, and multisystemic smooth muscle dysfunction syndrome. ACTA2 (commonly referred to as alpha-smooth muscle actin or α-SMA) is often...