by the NTHL1 gene. As reviewed by Li et al., NTHL1 is a bifunctional DNA glycosylase that has an associated beta-elimination activity. NTHL1 is usually...
10 KB (1,349 words) - 14:05, 29 March 2025
a012583. PMC 3683898. PMID 23545420. Kuiper RP, Hoogerbrugge N (2015). "NTHL1 defines novel cancer syndrome". Oncotarget. 6 (33): 34069–70. doi:10.18632/oncotarget...
52 KB (5,673 words) - 19:03, 5 April 2025
Several genes have been associated with polyposis, such as GREM1, MSH3, MLH3, NTHL1, RNF43 and RPS20. Familial adenomatous polyposis (FAP) is a form of hereditary...
30 KB (2,858 words) - 07:28, 25 May 2025
Dragon, Julie A; Doublié, Sylvie (2021-12-01). "Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis". Nucleic Acids...
5 KB (540 words) - 12:03, 16 May 2025
Vreede, Lilian; Walker, Romy; Win, Aung K. (December 2020). "Monoallelic NTHL1 Loss-of-Function Variants and Risk of Polyposis and Colorectal Cancer"....
136 KB (15,496 words) - 14:52, 24 May 2025
introducing a DNA strand break via the associated lyase reaction. OGG1 NTHL1 NEIL1 NEIL2 GRCh38: Ensembl release 89: ENSG00000109674 – Ensembl, May 2017...
1 KB (168 words) - 21:55, 28 July 2024
a012583. PMC 3683898. PMID 23545420. Kuiper RP, Hoogerbrugge N (2015). "NTHL1 defines novel cancer syndrome". Oncotarget. 6 (33): 34069–70. doi:10.18632/oncotarget...
43 KB (3,770 words) - 18:03, 27 November 2024
individuals. Among the 27 DNA repair genes evaluated, 13 DNA repair genes, MGMT, NTHL1, OGG1, SMUG1, ERCC1, ERCC2, ERCC3, ERCC4, MLH1, MLH3, RAD50, XRCC4 and XRCC5...
32 KB (3,857 words) - 22:04, 28 July 2024
concentration in the neurons, MUTYH responds by triggering their degeneration. NTHL1 NEIL1 GRCh38: Ensembl release 89: ENSG00000132781 – Ensembl, May 2017 GRCm38:...
23 KB (2,955 words) - 14:24, 29 March 2025
HGNC:25490 Q96HA8 10874 NTF3 HGNC:8023 P20783 10875 NTF4 HGNC:8024 P34130 10876 NTHL1 HGNC:8028 P78549 10877 NTM HGNC:17941 Q9P121 10878 NTMT1 HGNC:23373 Q9BV86...
282 KB (17 words) - 09:28, 10 February 2025
the 27 DNA repair genes evaluated, 13 DNA repair genes, MLH1, MLH3, MGMT, NTHL1, OGG1, SMUG1, ERCC1, ERCC2, ERCC3, ERCC4, RAD50, XRCC4 and XRCC5 were all...
28 KB (3,414 words) - 03:48, 7 November 2024
starting points for treatments against cancer and inflammatory diseases. MUTYH NTHL1 NEIL1 GRCh38: Ensembl release 89: ENSG00000114026 – Ensembl, May 2017 GRCm38:...
27 KB (2,803 words) - 22:04, 18 March 2025
lyase reaction (Bandaru et al., 2002)[supplied by OMIM] NEIL1 NEIL3 OGG1 NTHL1 GRCm38: Ensembl release 89: ENSMUSG00000035121 – Ensembl, May 2017 "Human...
7 KB (899 words) - 21:53, 28 July 2024
K, et al. (1999). "Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts...
14 KB (1,775 words) - 06:46, 28 December 2023
defective outcome in a mouse model of stroke.[citation needed] NEIL2 NEIL3 NTHL1 OGG1 GRCh38: Ensembl release 89: ENSG00000140398 – Ensembl, May 2017 GRCm38:...
14 KB (1,852 words) - 14:38, 29 March 2025
Vijayakrishnan J, Lubbe S, Chandler I, Houlston RS (2006). "Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer...
17 KB (2,233 words) - 02:15, 25 December 2024