biology, the NELF (negative elongation factor) is a four-subunit protein complex (NELF-A, NELF-B, NELF-C/NELF-D, and NELF-E) that negatively impacts transcription...
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that can phosphorylate the DRB sensitivity inducing factor (DSIF) and negative elongation factor (NELF), as well as the carboxyl terminal domain of the...
10 KB (1,397 words) - 12:01, 17 October 2024
is a human gene that encodes NELF-B. NELF-B is a subunit of negative elongation factor (NELF), which also includes NELF-A (WHSC2; MIM 606026), either...
11 KB (1,463 words) - 17:54, 20 November 2023
activity in producing mRNA. P-TEFb can also phosphorylate the negative elongation factor NELF (which pauses RNAP II within 60 nucleotides after mRNA initiation...
34 KB (3,549 words) - 00:09, 27 December 2024
Eukaryotic transcription (section Elongation factors)
sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex". Proceedings...
49 KB (5,867 words) - 10:43, 1 February 2025
transcription by RNA polymerase II (Pol II). It can interact with the negative elongation factor (NELF) to promote the stalling of Pol II at some genes, which...
7 KB (746 words) - 07:37, 28 October 2024
Negative elongation factor E is a protein that in humans is encoded by the RDBP gene. The protein encoded by this gene is part of a complex termed negative...
9 KB (1,207 words) - 04:46, 15 April 2024
transcription elongation by RNA Polymerase II. Sensitivity to DRB is dependent on DRB sensitivity inducing factor (DSIF), negative elongation factor (NELF),...
3 KB (103 words) - 16:39, 23 December 2024
Negative elongation factor A is a protein that in humans is encoded by the WHSC2 gene. This gene is expressed ubiquitously with higher levels in fetal...
8 KB (1,059 words) - 17:20, 12 August 2023
Transcription elongation factor SPT5 is a protein that in humans is encoded by the SUPT5H gene. SUPT5H has been shown to interact with: CDK9, Cyclin-dependent...
10 KB (1,231 words) - 02:49, 19 December 2023
accepted view was that sigma factor must dissociate upon transition from transcription initiation to transcription elongation (this transition is called...
20 KB (2,045 words) - 23:47, 25 October 2024
Negative elongation factor C/D is a protein that in humans is encoded by the TH1L gene. The NELF[clarification needed] complex of proteins interacts with...
8 KB (1,032 words) - 01:19, 28 July 2024
RNA elongation begins. TFIID will stay until elongation is finished. Subunits within TFIIH that have ATPase and helicase activity create negative superhelical...
12 KB (1,317 words) - 16:05, 14 March 2025
LHRH factor, a protein encoded by the NELF gene Near East Land Forces, a former part of the British Near East Command Negative elongation factor, a protein...
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Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in...
34 KB (4,512 words) - 06:26, 2 May 2025
Transcription (biology) (redirect from Rna elongation)
transcription elongation. In these organisms, the pausing induced by nucleosomes can be regulated by transcription elongation factors such as TFIIS. Elongation also...
58 KB (6,898 words) - 21:17, 23 March 2025
(2013). "Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae". PLOS...
184 KB (12,563 words) - 05:08, 10 March 2025
Dreier B, Barbas CF (2000). "Positive and negative regulation of endogenous genes by designed transcription factors". Proc. Natl. Acad. Sci. U.S.A. 97 (4):...
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Elongation factor RNA polymerase II-like 3 is a protein that in humans is encoded by the ELL3 gene. GRCh38: Ensembl release 89: ENSG00000128886 – Ensembl...
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Gravitropism (redirect from Negative geotropism)
asymmetric expansion of cells in a shoot-ward region to the tip known as the elongation zone. Differential growth during tropisms mainly involves changes in cell...
23 KB (2,797 words) - 16:23, 6 March 2025
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic...
75 KB (8,348 words) - 20:03, 18 March 2025
Estrogen receptor alpha (category Transcription factors)
alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor". Genes & Development. 18 (17): 2134–2146. doi:10.1101/gad.1214104...
58 KB (6,133 words) - 02:11, 17 March 2025
this context, tension is analogous to negative pressure. A rod under tension elongates. The amount of elongation and the load that will cause failure both...
8 KB (1,203 words) - 10:05, 21 February 2025
Transcription elongation factor A protein 2 is a protein that in humans is encoded by the TCEA2 gene. The protein encoded by this gene is found in the...
7 KB (950 words) - 10:54, 17 October 2022
Circular chromosome (section Elongation)
subtilis. Chromosome replication proceeds in three major stages: initiation, elongation and termination. The initiation stage starts with the ordered assembly...
21 KB (2,745 words) - 08:39, 17 November 2024
statements for the elongation at break : Research on alloys based on the purest shows an increasing elongation at break from about 20% elongation at 1% to 30%...
19 KB (1,987 words) - 01:47, 24 November 2024
Translational regulation (section Elongation)
nuclear membrane prevents this coupling in eukaryotes. Eukaryotic elongation factor 2 (eEF2) is a regulateable GTP-dependent translocase that moves nascent...
11 KB (1,481 words) - 11:25, 11 February 2024
toxin (Q5EK40). It inhibits elongation factor-2. It does so by ADP-ribosylation of EF2 using NAD+. This then causes the elongation of polypeptides to cease...
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Transcription elongation factor SPT4 is a protein that in humans is encoded by the SUPT4H1 gene. GRCm38: Ensembl release 89: ENSMUSG00000020485 – Ensembl...
7 KB (915 words) - 17:19, 12 May 2024
Proteus mirabilis (category Gram-negative bacteria)
process into a swarmer cell. This differentiation process includes the elongation of the cell 20 to 50 times longer than the vegetative cell, multinucleation...
12 KB (1,254 words) - 15:44, 30 April 2025